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High Quality Pharmaceutical Raw Material Conform USP Diethylstilbestrol 56-53-1 / 6898-97-1
Diethylstilbestrol Basic Info.:
Product Name: Diethylstilbestrol
Synonyms: Stilbestrol;Diethylstilbesterol;Domestrol;Grafestrol;Estrosyn;Fonatol;LABOTEST-BB LT00233101;
CAS: 56-53-1 / 6898-97-1
MF: C18H20O2
MW: 268.35
EINECS: 200-278-5
Assay: 99%
Melting point: 170-172 °C(lit.)
Storage temp.: 0-6°C
Solubility methanol: 0.1 g/mL, clear, faintly yellow
Stability: Isomerizes rapidly in Benzene, Chloroform, and Ether. Keep Shielded from light.
Water Solubility: Practically insoluble
Chemical Properties: White Solid
Product Categories: Miscellaneous Biochemicals;Intermediates & Fine Chemicals;Pharmaceuticals;STILBESTROL;Other APIs
Usage: Mainly used for low disease and estrogen hormone imbalance caused by functional bleeding, amenorrhea, can also be used before induction of labor stillbirth to increase myometrial oxytocin sensitivity.
Diethylstilbestrol Description:
Diethylstilbestrol (DES, former BAN stilboestrol) is a synthetic nonsteroidal estrogen that was first synthesized in 1938. It is also classified as an endocrine disruptor. Human exposure to DES occurred through diverse sources, such as dietary ingestion from supplemented cattle feed and medical treatment for certain conditions, including breast and prostate cancers.:)
From about 1940 to 1971, DES was given to pregnant women in the mistaken belief it would reduce the risk of pregnancy complications and losses.:)
In 1971, DES was shown to cause a rare vaginal tumor in girls and women who had been exposed to this drug in utero. The United States Food and Drug Administration subsequently withdrew DES from use in pregnant women. Follow-up studies have indicated that DES also has the potential to cause a variety of significant adverse medical complications during the lifetimes of those exposed.:)
The United States National Cancer Institute recommends women born to mothers who took DES undergo special medical exams on a regular basis to screen for complications as a result of the drug. Individuals who were exposed to DES during their mothers' pregnancies are commonly referred to as "DES daughters" and "DES sons".
Diethylstilbestrol Application:
A synthetic, nonsteroidal estrogen. Recomended solvents are DMSO, DMF and ethanol, even in these solvents do not store in solution for any prolonged period of time.
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