Pharmaceutical raw materials used in synthesizing new medications

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Pep1-AGL LAB GRADE

Creative Peptides is specialized in the process development and the manufacturing of bioactive peptides. We are dedicated to offering custom peptide synthesis, process development, GMP manufacturing as well as catalog products for customers in industry and research area. Visit https://www.creative-peptides.com/product/pep1-agl-item-r0833-34635.html for more information.

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Pep1-TGL LAB GRADE

Creative Peptides is specialized in the process development and the manufacturing of bioactive peptides. We are dedicated to offering custom peptide synthesis, process development, GMP manufacturing as well as catalog products for customers in industry and research area. Visit https://www.creative-peptides.com/product/pep1-tgl-item-r0834-34636.html for more information.

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Peptides 170851-70-4 Weight Loss Steroids Ipamorelin For Muscle Gain

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Peptides 170851-70-4 Weight Loss Steroids Ipamorelin For Muscle Gain
 
Ipamorelin Basic Info.:
 
Product Name: Ipamorelin
Synonyms: IpoMarelin;IpaMorelin Acetate;Aib-His-D-2-Nal-D-Phe-Lys-NH2
Unit Size: 2 mg/vial
Unit Quantity: 1 Vial
CAS NO.: 170851-70-4
Molecular Formula: C38H49N9O5
Molecular Weight: 711.85
Sequence: H-Aib-His-D-2-Nal-D-Phe-Lys-NH2
Appearance: White Powder
Purity: 98.49%
Identity (ESI-MS) 711.85±0.5
Source Chemical Synthesis
Storage: Stable at room temperature for 90 days,however it should be stored in a freezer below -8°C for any extended period of time. After reconstituting Ipamorelin should be refrigerated at temperatures not to exceed 36°F.
 
Ipamorelin Description:
 
Ipamorelin is a fascinating new muscle building discovery that is getting a lot of attention in the bodybuilding world. It is a synthetic peptide that has powerful Growth Hormon releasing properties. And these GH releasing properties are what is of interest to athletes and bodybuilders since they can make a tremendous difference in the amount of muscle you can grow and how quickly you burn fat.
 
Ipamorelin is a penta-peptide. (Aib-His-D-2-Nal-D- Phe-Lys-NH2) And, the strength it displays may very well make regular old Growth Hormon (GH) obsolete. But what athletes and bodybuilders really want to know is what is this wonder peptide capable of doing, how is it used, and how does it compare to the other GHRP peptides?
 
Athletes are taking Ipamorelin in a 200mcg -300mcg dosage, two or three times daily, using a tiny insulin needle to inject. They usually start with the lower dose since side effects can include headaches or what feels like a head-rush. Ipamorelin can be taken at anytime but taking it about 30-45 minutes before a workout would seem ideal because of the pulse in Growth Hormon (GH) it creates allowing for maximum growth.
 
Studies on the effects of Ipamorelin on bone growth, body weight, and GH release showed some interesting conclusions.In one experiment, various doses were administered over the course of 15 days to test the group's reactions.
 
There was a distinct and dose-dependent effect on body weight gain however, the treatment group did not show a change in total IGF-I levels. Nor did the treatment group produce serum markers of bone development. For example, the number of cells in the wide portion of the tibia (the shinbone) did not change significantly. This is a good thing because it suggests muscle growth with less potential for deformity of bone or cartilage.
 
Ipamorelin in theory may increase Acetylchloine or Cortisol when used in higher dosages. However, and increase in Acetylchloine or Cortisol is even more likely with GHRP-2 and GHRP-6. In fact, in the case of Ipamorelin, there was little to no rise in Acetylcholine and Cortisol blood plasma levels even at injections more than 200 times higher than the effective dosage for comparable GH release.
 
Ipamorelin Applications:
 
Ipamorelin is a selective growth hormon secretagogue and agonist of the ghrelin receptor. In pentobarbital anaesthetised rats, ipamorelin released GH with a potency and efficacy comparable to GHRP-6 (ED50 = 80±42 nmol/kg and Emax = 1545±250 ng GH/ml vs 115±36nmol/kg and 1167±120ng GH/ml). In conscious swine, ipamorelin released GH with an ED50 = 2.3±0.03 nmol/kg and an Emax = 65±0.2 ng GH/ml plasma. Again, this was very similar to GHRP-6 (ED50 = 3.9±1.4 nmol/kg and Emax = 74±7ng GH/ml plasma). GHRP-2 displayed higher potency but lower efficacy (ED50 = 0.6 nmol/kg and Emax = 56±6 ng GH/ml plasma). The specificity for GH release was studied in swine.
 

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Peptides Alarelin Acetate For Ovulation And Endmometriosis 79561-22-1

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Peptides Alarelin Acetate For Ovulation And Endmometriosis 79561-22-1 
 
Alarelin Acetate Basic Info.:
 
Product Name: Alarelin Acetate
Synonyms: Des-Gly10,[D-Ala6]-Lh-Rh Ethylamide Acetate Salt.
CAS: 79561-22-1
MF: C56H78N16O12
MW: 1167.32
Storage temp.: −20°C
Form: Powder
Product Categories: Amino Acid Derivatives;Peptide;LH-RH;LH-RHPeptides for Cell Biology;Neuropeptides;Releasing Factors;API.
 
Alarelin Acetate (79561-22-1) Description:
 
Alarelin acetate is a gondatrophin releasing hormone. Natural forms of alarelin found in animals are used to induce ovulation. Synthetic versions of this product are created using an LH-RH antagonist which is commonly set in larger doses than the natural LH-RH that is typically found in the rat hypophyseal stimulation or the gondatoropin secretions in induced ovulation or in vitro.
 
This chemical is the acetate form of the natural hypothalamic peptide which is used by an animal’s body to release LH and FSH from the pituitary gland. The peptide alarelin acetate has a single non-glycosylated polypeptide structure that is made up of nine amino acids. This has a molecular mass of 1167.3.
 
Alarelin is commonly used in research settings both to better understand this peptide’s effects on an animal’s body and to induce conditions that may assist with reproductive research. Samples of this chemical intended for research settings are typically stable for around three weeks at room temperature, and will need to be stored at temperatures below -18 degrees Celsius for long term use.
 
Most versions of this chemical are shipped as a lyophilized powder that can be reconstituted at a sterile temperature. This chemical may remain stable for up to three weeks at room temperature if it is kept sealed when it is not in use. If this product will be used for long periods of time is should be kept in a freezer with a waterproof sea.
 
If the mixture has already been reconstituted it can be kept at 40 degrees Celsius for 2-7 days but should be kept at -180 degrees Celsius for longer periods of time. Do not continually refreeze and thaw the product.
 

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Peptides Carbetocin Acetate Contracting Uterus Control Bleeding 37025-55-1

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Peptides Carbetocin Acetate Contracting Uterus Control Bleeding 37025-55-1
 
Carbetocin Acetate Basic Info.:
 
Product Name: Carbetocin Acetate
Synonyms: (Butyryl1,Tyr(Me)2)-1-Carbaoxytocin Trifluoroacetate Salt;Carbetocin;Carbetocin Trifluoroacetate Salt;
CAS: 37025-55-1
MF: C45H69N11O12S
MW: 988.17
EINECS: 253-312-6
Storage temp.: -15°C
Product Categories: Peptide;Vasopressin and Oxytocin receptor;Intermediates & Fine Chemicals;Pharmaceuticals;Other APIs
Usage: An obstetric drug used to control postpartum hemorrhaging.
 
Carbetocin Acetate it is used to control bleeding after giving birth. Like oxytocin, it causes contraction of the uterus.
 

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Perilipin-2 (129-137) LAB GRADE 97%

Creative peptides is specialized in the process development and the manufacturing of bioactive peptides. We offer custom peptide synthesis, process development, GMP manufacturing as well as catalog products. We supply Perilipin-2 (129-137).http://www.creative-peptides.com/product/perilipin-item-ta-308-20928.html

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Peroxiredoxin-5, mitochondrial (163-172) LAB GRADE 97%

Creative peptides is specialized in the process development and the manufacturing of bioactive peptides. We offer custom peptide synthesis, process development, GMP manufacturing as well as catalog products. We supply Peroxiredoxin-5, mitochondrial (163-172).http://www.creative-peptides.com/product/peroxiredoxin-mitochondrial-item-ta-230-15741.html

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Pharma Antiviral Agents Tenofovir Disoproxil Fumarate 202138-50-9 For Medicine Ingredients

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Pharma Antiviral Agents Tenofovir Disoproxil Fumarate 202138-50-9 For Medicine Ingredients

 

Tenofovir Basic Info.:

 

Product Name: Tenofovir

CAS:147127-20-6

MF: C9H14N5O4P

MW:287.21

mp:276-280°C

storage temp. Store at -20°C

Water Solubility :13.4 mg/mL (25 ºC)

Chemical Properties:White Crystalline Solid

Usage:Acyclic phosphonate nucleotide analogue. Used as an anti-HIV agent

Usage:Acyclic phosphonate nucleotide analogue; reverse transcriptase inhibitor. Used as an anti-HIV agent. Antiviral.

Usage:Tenofovir blocks reverse transcriptase and hepatitis B virus infections.

Biological Activity Selectively inhibits HIV reverse transcriptase (RNA-dependent DNA polymerase). Prevents cytotoxicity in SIV-infected C-8166 cells in vitro (IC 50 = 1.5 μ M). Antiviral agent.

 

Tenofovir Usage And Synthesis:

 

1. Antiviral drugs, Tenofovir is an acyclic nucleoside antiviral reverse transcriptase inhibitor. The active substance is Tenofovir disoproxil, while tenofovir is a prodrug that is used because of its better absorption in the gut.

2. Tenofovir can inhibit viral polymerase through direct competitively combine with natural deoxyribose or by insertion to terminate chain of human DNA. It is the first nucleotide analogs to treat HIV-1 infection that approved by the US Food and Drug Administration (FDA).

3. Tenofovir is a main medicine in AIDS cocktail therapy, researches has shown that it can effectively improve the monkeys` ability on prevention of immunodeficiency virus (similar to the human AIDS virus).

 

Tenofovir Pharmacokinetics:

 

Tenofovir is hardly absorbed through the gastrointestinal tract, for this reason, prodrug of Tenofovir has been developed by esterification, and then to make tenofovir fumarate ester. Tenofovir ester is water-soluble, can be rapidly absorbed and degraded into the active tenofovir, and then was metabolized to the active Tenofovir disoproxil. Tenofovir will reach the peak of plasma Concentration within 1-2 h after administration. When combined with food service, the bioavailability of Tenofovir can be increased by 40%. Intracellular half-life of Tenofovir disoproxil is about 10 h, it needs dosing everyday. Because Tenofovir is not a CYP-450 substrate, this may decrease the possibility of interactions with other drugs caused by CYP450. Elimination of Tenofovir is by glomerular filtration and active tubular secretion. Approximately 70% to 80% is recovered in urine as unchanged drug. Elimination half-life is approximately 17 h.

 

Indications: Tenofovir is indicated for the treatment of HIV, HBV infection. This product also can cooperated with other reverse transcriptase inhibitors for HIV-1 infection and hepatitis B treatment.

 

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Pharmaceutical Aerosols Hfa-134A Purified ?99.99

Any interested, please contact  us: katty@xmjuda.com

Pharmaceutical product HFA-134A (P) obtained in 2016 the DMF file number in USA

HFA-134 Chemical Name: Pharmaceutical Excipients Tetrafuoroethane

The Relative Name: Aerosol Medication, Propellant Hfa-134a, Prokinetic Agents, Propellant R134a, Aerosol Inhaler, Inhalation Aerosol, Hfa Inhaler

Cas No.: 711-97-2

Molecular Formula: CH2FCF3         

Physical Properties:

Molecular weight(g/mol):  102.3         Melting point℃: -103.15℃

r134a boiling point: -26.1℃

Density of liquid (25℃ ): 1.207 g/cm3     Vapour pressure(25℃): 0.665MPa

Critical temperature (℃): 101.1           Critical pressure: 4.067 MPa

R134a Density: 1.206g/cm3             Latent heat of evaporation in boiling point: 215.0KJ/kg

Solubility in water (25℃): 0.15 W%       Specific heat (25℃ liquid): 1.51 KJ/kg . k 

ODP: 0                              GWP(100yr): 1200 

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Pharmaceutical Chemicals Isotretinoin Accutane For AcneTreatment 4759-48-2

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Pharmaceutical Chemicals Isotretinoin Accutane For AcneTreatment 4759-48-2

Isotretinoin Basic Info.:

Product Name: Isotretinoin

Synonyms: 13-ra;Accutane;Isoretinoin;Isotrex;Neovitaminaacid;Ro-4-3780

CAS: 4759-48-2

MF: C20H28O2

MW: 300.44

Assay: 99%

EINECS: 225-296-0

Product Categories: Antibiotics;Organic acids;APIs;Intermediates & Fine Chemicals;Pharmaceuticals;Retinoids

Air & Water Reactions: Insoluble in water.

Packing:100g/foil bag

Chemical Property: The melting point of 174~175 Centigrade.

UV maximum absorption: 354nm ( 39800).

Usage: Used as a treatment for severe acne. Presently being studied in conjuction with the treatment of photoaged skin.

Isotretinoin Usage:

As the retinoid, there are strong and fast proliferation inhibition and differentiation of skin gland cell function, effective on severe nodular cystic acne. The gastrointestinal absorption is better, while the local medication invalid. Other drugs used to treat invalid serious acne, cystic acne, acne conglobata, rosacea, ichthyosis, keratosis follicularis and pityriasis rubra pilaris and other skin diseases also have a certain effect. For severe acne. Anti skin dyskeratosis medicine. For the treatment of severe acne and other disorders. Belong to whitening prohormones, can made INTO injections! Works very well in whitening!

Application Of Isotretinoin:

1. Medical applications: the lack of nutrition of the elderly, thin, for severe burns and had the operation people.

2. Sports purpose: promote muscle growth, increased training and endurance training load, it has never been proved.

3. Adaption: Trauma, chronic infection, malnutrition and wasting disease and All kinds of refractory anemia.

 

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