Pharmaceutical raw materials used in synthesizing new medications

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Pharmaceutical Raw Material Flutamide For Cancer Treament 13311-84-7

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Pharmaceutical Raw Material Flutamide For Cancer Treament 13311-84-7
 
Flutamide Basic Info.:
 
Product Name: Flutamide 
Synonyms: Timtec-bb sbb006930;Flutamide;Aurora ka-860
CAS: 13311-84-7 
MF: C11H11F3N2O3 
MW: 276.21 
EINECS: 236-341-9 
Chemical Properties: Light Yellow Solid 
Standard: Enterprise Standard 
Packing: foil bag or as required
Product Categories: Antitumors for Research and Experimental Use;Biochemistry;Amines;Aromatics;Pharmaceutical raw material 
 
Flutamide Usage:
 
Neuroleptic, Flutamide is a nonsteroidal antiandrogen drug, antineoplastic (hormonal). 
 
Flutamide Features:
 
For prostate cancer or benign prostatic hypertrophy. This product with bright prolyl Lee Teuk combination (should also start and at the same time, the continued use of) for the treatment of metastatic prostate
cancer, can significantly increase the efficacy.
 

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Pharmaceutical Raw Material For Vitamin C Ascorbic Acid 50-81-7

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Pharmaceutical Raw Material For Vitamin C Ascorbic Acid 50-81-7
 
Vitamin C Basic Info.:
 
Product Name: Vitamin C
Synonyms: L-Ascorbic Acid, Free Acid; Vitamin C; L-(+)-Ascorbic acid; VC; Ascorbic acid; Vita C BP2005; Vitamine C;
Assay: 98%
CAS No.: 50-81-7
EINECS No.: 200-066-2
Molecular Formula: C6H8O6
Molecular Weight: 176.12
Melting point: 190-194 ° C (DEC. )
Boiling point: 552.672° C at 760 mmHg
Flashing point: 238.199° C
Water solubility: 333 g/L (20º C)
Appearance: White crystalline powder
Packing: 25KG/Drum
Application: To cure Scurvy
 
Vitamin C Description:
 
Vitamin C or L-ascorbic acid, or simply ascorbate (the anion of ascorbic acid), is an essential nutrient for humans and certain other animal species. Vitamin C refers to a number of vitamers that have vitamin C activity in animals, including ascorbic acid and its salts, and some oxidized forms of the molecule like dehydroascorbic acid. Ascorbate and ascorbic acid are both naturally present in the body when either of these is introduced into cells, since the forms interconvert according to pH.
 
Vitamin C is a cofactor in at least eight enzymatic reactions, including several collagen synthesis reactions that, when dysfunctional, cause the most severe symptoms of scurvy. [1] In animals, these reactions are especially important in wound-healing and in preventing bleeding from capillaries. Ascorbate may also act as an antioxidant against oxidative stress. [2] However, the fact that the enantiomer D-ascorbate (not found in nature) has identical antioxidant activity to L-ascorbate, yet far less vitamin activity, [3] underscores the fact that most of the function of L-ascorbate as a vitamin relies not on its antioxidant properties, but upon enzymic reactions that are stereospecific. "Ascorbate" without the letter for the enantiomeric form is always presumed to be the chemical L-ascorbate.
 
Vitamin C Application:
 
Scurvy is an avitaminosis resulting from lack of vitamin C, since without this vitamin, the synthesized collagen is too unstable to perform its function. Scurvy leads to the formation of brown spots on the skin, spongy gums, and bleeding from all mucous membranes. The spots are most abundant on the thighs and legs, and a person with the ailment looks pale, feels depressed, and is partially immobilized. In advanced scurvy there are open, suppurating wounds and loss of teeth and, eventually, death. The human body can store only a certain amount of vitamin C, [41] and so the body stores are depleted if fresh supplies are not consumed. The time frame for onset of symptoms of scurvy in unstressed adults on a completely vitamin C free diet, however, may range from one month to more than six months, depending on previous loading of vitamin C.
 

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Pharmaceutical Raw Material Griseofulvin For Health Skin Tinea Inhibition 126-07-8

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Pharmaceutical Raw Material Griseofulvin For Health Skin Tinea Inhibition 126-07-8 
 
Griseofulvin Basic Info.:
 
Product Name: Griseofulvin
Synonyms: (+)-GRISEOFULVIN;GRISEOFULVIN;
CAS: 126-07-8 
MF: C17H17ClO6 
MW: 352.77 
EINECS: 204-767-4 
Chemical Properties: Crystalline Solid 
 
(+)-Griseofulvin Usage:
 
1.Adrenegic blocker, Ca channel blocker, coronary vasodilator, antiarrhythmic. 
2.Antifungal, inhibits mitosis in metaphase.
3.Griseofulvin is a spirobenzofuran produced by a number of Penicillium species, first isolated in the 1930s by Raistrick's group. Griseofulvin is a selective antifungal agent used to treat skin infections in animals and humans. Griseofulvin acts by binding to fungal tubulin and inhibiting the mitotic spindle. Griseofulvin's ability to bind to keratin is considered an important aspect of the metabolite's access to dermatophytic fungi. More recently, griseofulvin has become an important phenotypic marker in Penicillium taxonomy. 
4.It is an antifungal drug. It is used both in animal and in humans, to treat rigworm infections of the skin and nails. It is derived from the mold Penicillium griseofulvum.
 

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Pharmaceutical Raw Material Hydroxypropyl Beta Cyclodextrin 128446-35-5 For Food

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Pharmaceutical Raw Material Hydroxypropyl Beta Cyclodextrin 128446-35-5 For Food
 
Hydroxypropyl Beta Cyclodextrin Basic Info.:
 
Product Name: Hydroxypropyl-Beta-Cyclodextrin
Name: (2-HYDROXYPROPYL)-BETA-CYCLODEXTRIN
CAS NO: 128446-35-5
MF: C63H112O42
MW: 1541.54
EINECS: 420-920-1
Assay: 99%
Packing: 10kg/drum
Appearance: White powder
Characteristics and Uses: The introduction of hydroxypropyl β - cyclodextrin breaking intramolecular hydrogen bond ring, while maintaining the cyclodextrin cavity while overcoming the poorly water-soluble β - cyclodextrin major drawback. Is currently the most in-depth study, the most widely used one cyclodextrin derivatives. Mainly used in food, pharmaceutical, cosmetics industries.
 
Product Description Of Hydroxypropyl Beta Cyclodextrin:
 
1, In the food, spices fields, can improve the stability and long-term nutritional molecules, can mask or correct nutritional elements of food smells and tastes bad, you can improve the production process and product quality. The product is very good solubility in water, the degree of substitution can be 4 or more miscible in any proportion with water, 50 % ethanol and methanol can also be dissolved.
2, In cosmetic raw materials used as a stabilizer, emulsifier, to taste and the like, organic molecules can be reduced in cosmetics mucosal tissue irritation on the skin, enhance the stability of active ingredients, to prevent volatilization of nutrients, oxidation. It has a certain relative hygroscopicity.
3, In the pharmaceutical industry, due to the relative surface activity and hemolytic activity is relatively low and is not irritating to muscle, so it is an ideal injection solubilizer and pharmaceutical excipients. Insoluble drugs can increase the water solubility, increased drug stability, improved bioavailability, efficacy of the pharmaceutical dosage increase or decrease, can be adjusted or controlled drug release rate, reduce drug side effects.
4. For oral drugs, injections, drug delivery systems (including nasal, rectal, cornea, etc.), transdermal drug delivery systems for targeted drug lipophilic carrier protein can be used as protective agents and stabilizers.
 

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Pharmaceutical Raw Material Metformin HCl Hydrochloride CAS 1115-70-4

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Pharmaceutical Raw Material Metformin HCl Hydrochloride CAS 1115-70-4
 
Metformin HCL Basic Info.:
 
Product Name: Metformin HCL
Metformin Hydrochloride; 3-(diaminomethylidene)-1,1-dimethylguanidine hydrochloride
CAS No.: 1115-70-4
EINECS: 214-230-6
Molecular Formula: C4H12ClN5
Molecular Weight: 165.6246
Melting Point: 220~225 °C.
Appearance: white crystalline powder; odorless.  soluble in water, dissolved in methanol, slightly soluble in ethanol, insoluble in chloroform or ether. 
Absorption coefficient of this product, accurately weighed, dissolved in water and diluted quantitatively per 1ml solution containing 5μg. According to the spectrophotometric determination of absorbance at 233nm wavelength, the absorption coefficient of 778 ~ 818.
 

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Pharmaceutical Raw Materials Cabergoline 81409-90-7 Used To Parkinson's Disease

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Pharmaceutical Raw Materials Cabergoline 81409-90-7 Used To Parkinson's Disease
 
Cabergoline Basic Info.:
 
Product Name: Cabergoline
Synonyms: Cabergoline;Cabaser;Dostinex;Dostine;FCE-21336
CAS: 81409-90-7
MF: C26H37N5O2
MW: 451.6
Purity: 99%
Melting Point: 102-104°C
Storage temp.: Store at +4°C
Chemical Properties: White Crystalline Solid
Product Categories: Intermediates & Fine Chemicals;Neurochemicals;Pharmaceuticals;API.
Usage: A dopamine D2-receptor agonist.Receptor stimulant.
Packing: Foil bag or as requirments.
 
Cabergoline Description:
 
Cabergoline is a dopamine agonist designed to reduce prolactin. In medical circles it is commonly used to combat prolactinomas, a benign tumor of the pituitary gland that may cause an excess production of prolactin. It is also used by athletes who supplement with anabolic steroids that may increase prolactin levels 
 
Cabergoline, most commonly sold under the brand name Dostinex, is not a new drug as it was first developed in 1981 by the Italian drug manufacture Farmitalia-Carlo Erba Spa. The drug was later acquired by Pharmacia and then found its resting place with Pfizer in 2002.
 
Cabergoline Functions and Traits:
 
As a dopamine agonist, Cabergoline directly correlates with the long acting D2 receptor thereby inhibiting the secretion of prolactin in the body and in turn lowering serum prolactin levels. As a dopamine agnonist, Cabergoline is used to treat Parkinson's disease, hyperprolactinaemia (abnormally high levels of prolactin in the blood), Cushing's disease and as mentioned prolactinomas.
 
Cabergoline's direct function (specifics) is in that it inhibits prolactin secretion in the pituitary's lactotroph cells. It really is a very simple drug and what's simpler or perhaps interesting is that the simple medication was discovered almost accidently during experiments with ergot alkaloids.
 
Uses in Medicine:
 
There are many uses that the medical world is discovering for dostinex. They include hyperprolactinemia, prolactin producing tumors, Parkinson's disease, Cushing's disease, and a myriad of other ailments.
 
One of the best known uses for cabergoline is in tumors and cancers related to high prolactin levels. In fact, it's been an industry leading drug when it comes to shrinking prolactin-secreting macroadenomas.
 
Bodybuilding Uses:
 
There are several ways we can use caber in bodybuilding. Since it is a dopamine agonist, some athletes believe they can take it to give themselves an adrenaline rush during a sporting event. Also, the addition of dopamine can improve motor skills and give you an edge over your competition. In theory, you will be able to workout much harder and be able to ignore pain pushing your muscles to the limit.
 
The main way bodybuilders use cabergoline is when they run a compound which increases prolactin levels in the body. Trenbolone will turn into prolactin, and, when abused, you can get prolactin based gynecomastia. In addition, a spike in prolactin can cripple your sex drive. Even when you do not run a compound that increases prolactin, caber can still help normalize your libido when you are playing with your hormones.
 
Another way caber can be used in bodybuilding is by its mechanism of mimicking dopamine being produced from food intake. Ever had a craving for New York style greasy pizza, oreo ice cream or some other treat you know you shouldn't have? Well, when you take cabergoline, the dopamine being released can act as the pleasure chemical, which can make a bite of that pizza satisfy you rather than eating the whole pie. This aids weight loss goals and helps you stay lean.
 
And finally, sleep! Many bodybuilders who take cabergoline report improved sleep thanks to the dopamine mimic. This allows you to sleep more, deeper and longer.
 

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Pharmaceutical Raw Materials Chondroitin Sulphate Powder 9007-28-7

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Pharmaceutical Raw Materials Chondroitin Sulphate Powder 9007-28-7
 
Chondroitin Sulphate Basic Info.:
 
Product Name: Chondroitin Sulphate
Synonyms: Poly-1(2/3)-N-acetyl-2-amino-2-deoxy-3-O-beta-D-glucopyranurosyl-4-(6)sulfonyl-D-galactose
Molecular Formula: (C14H21NO14S)n
CAS No.: 9007-28-7
EINECS No.: 232-696-9
Standard: USP29
Appearance: White or almost white powder
Assay (dried basis, by CPC): 90.0%~105.0%
Assay (dried basis, by HPLC): 90.0%~105.0%
State of solution (absorbance): 0.35 max. At 420nm
Loss on drying: 10% max.
pH (1% solution): 5.5~7.5
Particle Size: 100%through 80mesh
Residue on ignition (dried basis): 20.0%~30.0%
Chloride [Cl-]: 0.5% max.
Sulfate [SO4]: 0.24% max.
Bulk Density: 0.6g/ml min
Protein (dried basis): 6.0% max.
Heavy metals: 20ppm max
Total Plate Count: 1000cfu/g max.
Total Yeast & Mold: 100cfu/g max.
E. Coli.: Not detected
Salmonella: Not detected
Clostridium: Not detected
 
Chondroitin Sulphate Applications:
 
As the chitosan non-toxic,has anti-bacterial, anti-inflammatory, hemostatic, and immune function, can be used as artificial skin, self-absorption of surgical sutures, medical dressing Branch, bone, tissue engineering scaffolds, enhance liver function, improve digestive function, blood fat, lowering blood sugar, inhibiting tumor metastasis, and adsorption and complexation of heavy metals and can be excreted, and so on, was vigorously applied to health food and drug additives.
 

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Pharmaceutical Raw Materials Desonide Used To Treat Atopic Dermatitis 638-94-8

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Pharmaceutical Raw Materials Desonide Used To Treat Atopic Dermatitis 638-94-8
 
Desonide Basic info:
 
Product Name: Desonide
Synonyms: Prednacinolone;Desonide;D-2083;Steroderm
CAS NO.: 638-94-8
Molecular Formula: C24H32O6
Molecular Weight: 416.51
EINECS: 211-351-6
Assay: 99.5%
Melting point: 272-274°C
Storage temp.: Refrigerator
Appearance: White powder
Product Categories: Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals;Steroids;SPORANOX;Hormone Drugs.
Usage: 
(1)With acetal-based adrenal cortex hormones;
(2)Antifungal;
(3)Anti-inflammatory. Desonide has also been found as an impurity in budesonide (B689490).
How to use desonide topical: Use this medication only on the skin.
 
Desonide Description:
 
Desonide Ointment, 0.05% contains Desonide (Pregna - 1,4 - diene - 3,20 - dione,11,21 - dihydroxy - 16,17 - [(1 - methylethylidene)bis(oxy)] - ,(11β,16α)) a synthetic corticosteroid for topical dermatologic use. The corticosteroids constitute a class of primary synthetic steroids used topically as anti-inflammatory and antipruritic agents.
 
Chemically, Desonide, the active ingredient in Desonide Ointment, 0.05% is C24H32O6. It has the following structural formula:
 
The molecular weight of Desonide is 416.51. It is a white to off-white powder. The solubility of Desonide in distilled water saturated with ether is 184 mg/L.
Each gram of Desonide Ointment, 0.05% contains 0.5 milligram of Desonide microdispersed in a base of white petrolatum.
 
Desonide Application:
 
Desonide belongs to the group of medications known as topical corticosteroids. It is used to Treat various skin conditions, including rashes. It works by reducing inflammation and itching.
 
Endogenous eczema clinical cure rate, the overall curative effect is distinct, and the low Incidence of adverse reactions, is a safe and effective external cortex hormone.
 
Wash your hands. Before applying the medication, clean and dry the affected area. Apply a thin film of the medication to the affected area and gently rub in, usually 2-3 times daily, or as directed by your doctor. If using the gel, apply the gel usually only 2 times daily. Do not bandage, wrap, or cover the area unless you are instructed to do so by your doctor. If used in the diaper area on an infant, do not use tight-fitting diapers or plastic pants.
 
After applying the medication, wash and dry your hands, unless you are using this medication to treat the hands. When applying this medication near the eyes, avoid getting it in the eyes because this may worsen or cause glaucoma, or cause irritation. Also, avoid getting this medication in the nose or mouth. If you get this medication in your eyes, nose, or mouth, rinse immediately with plenty of water.
 

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Pharmaceutical Raw Materials Dexamethasone Sodium Phosphate For Acute Disorders 2392-39-4

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Pharmaceutical Raw Materials Dexamethasone Sodium Phosphate For Acute Disorders 2392-39-4
 
Dexamethasone Sodium Phosphate Quick Detail:
 
Product name: Dexamethasone Phosphate Sodium
Synonyms: Dexamethasone sodium phosphate; Dexamethasone Phosphate Sodium; dexamethasone 21-(disodium phosphate); Dexamethasone Sodium Phosphate; Dexamethasone Phosphate Disodium
CAS: 2392-39-4
M.F.: C22H28FNa2O8P 
M.W.: 516.4
Usage : pharmaceutical raw materials, the hormone
Assay: 99%
Packaging Details: Foil bag or as requirement 
Payment Terms: T/T, Western Union, MoneyGram
Shipping way: EMS, HKEMS, DHL, Fedex, UPS (you can choose the fastest and your favourite)
 
Description of Dexamethasone Sodium Phosphate:
 
Dexamethasone sodium phosphate, a corticosteroid, is similar to a natural hormone produced by your adrenal glands. It often is used to replace this chemical when your body does not make enough of it. It relieves inflammation (swelling, heat, redness, and pain) and is used to treat certain forms of arthritis; skin, blood, kidney, eye, thyroid, and intestinal disorders (e.g., colitis); severe allergies; and asthma. Dexamethasone sodium phosphate is also used to treat certain types of cancer.
 
Dexamethasone sodium phosphate comes as a tablet and a solution to take by mouth. Your doctor will prescribe a dosing schedule that is best for you. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Dexamethasone sodium phosphate exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
 
Applications of Dexamethasone Sodium Phosphate:
 
Do not stop taking Dexamethasone sodium phosphate without talking to your doctor. Stopping the drug abruptly can cause loss of appetite, upset stomach, vomiting, drowsiness, confusion, headache, fever, joint and muscle pain, peeling skin, and weight loss. If you take large doses for a long time, your doctor probably will decrease your dose gradually to allow your body to adjust before stopping the drug completely. Watch for these side effects if you are gradually decreasing your dose and after you stop taking the tablets or oral liquid, even if you switch to an inhalation corticosteroid medication. If these problems occur, call your doctor immediately. You may need to increase your dose of tablets or liquid temporarily or start taking them again.
 

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Pharmaceutical Raw Materials Diclofenac Sodium For Antipyretic Analgesics 15307-79-6

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Pharmaceutical Raw Materials Diclofenac Sodium For Antipyretic Analgesics 15307-79-6
 
Diclofenac Sodium Basic Info.:
 
Product Name: Diclofenac sodium 
Synonyms: diclophenacsodium;gp45840;huma-difenac 
CAS: 15307-79-6 
MF: C14H10Cl2NNaO2 
MW: 318.13 
EINECS: 239-346-4 
MP:288-290°C 
storage temp. -20°C Freezer 
solubility  H2O: 50 mg/mL
Chemical Properties: White Crystalline powders
Usage : Pharmaceutical intermediates .
Product Categories: Organics;Intermediates & Fine Chemicals;Pharmaceuticals
 
Product Introduction Of Diclofenac Sodium:
 
As an anti-inflammatory and analgesic drug; It's a kind of active pharmaceutical ingrddients, Nonsteroidal anti-inflammatory analgesic to relieves pain and reduces inflammation (swelling). used to treat headaches, muscle aches, dental pain, and athletic injuries. For the goods potent antipyretic analgesic anti-inflammatory drug. Its anti-inflammatory effect of indomethacin in a range of 2-2.5 times stronger than aspirin 26-50 times. In rheumatoid arthritis, osteoarthritis, post-operative pain and various causes of fever.
  
Diclofenac Sodium Avail:
 
Diclofenac sodium: nonsteroidal anti-inflammatory drug (NSAID) which is primarily used to help treat the symptoms of arthritis.
Diclofenac sodium: These medications can help reduce the swelling and inflammation caused by the disease to help provide comfort to the patient.
Diclofenac sodium: used to help relieve the symptoms of rheumatoid arthritis, osteoarthritis, pain, inflammation, swelling, stiffness and joint pain. In some cases, this medication will be used as part of a treatment regimen for ankylosing spondylitis, menstrual cramps or acute migraine attacks.
 

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