Pharmaceutical raw materials used in synthesizing new medications

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Pharmaceutical Raw Materials Respiratory System Drugs Roflumilast For COPD 162401-32-3

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Pharmaceutical Raw Materials Respiratory System Drugs Roflumilast For COPD 162401-32-3
 
Roflumilast Basic Info.:
 
Product Name: Roflumilast
Synonyms: ROFLUMILAST;3-(Cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)benzamide;B 9302-107;BY 217;BYK 20869;Daxas;Roflumilast / 3-(cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide;3-(Cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide 
CAS: 162401-32-3 
MF: C17H14Cl2F2N2O3 
MW: 403.21 
MP: 158°C 
Purity: 99%
Storage temp.: Refrigerator 
Chemical Properties: Crystallin Solid 
Usage: Selective phosphodiesterase 4(PDE4) inhibitor. Antiasthmatic; in treatment of chronic obstructive pulmonary disease 
Usage: API
Package: 1KG foil bag; 25Kg drum
 
Roflumilast Description:
 
Roflumilast is a phosphodiesterase-4 (PDE-4) inhibitor. Due to its selective inhibition of the PDE4 isoenzyme in lung cells, roflumilast is indicated for the management of chronic obstrtuctive pulmonary disease (COPD) exacerbations. Treatment with Roflumilast is associated with an increase in psychiatric adverse reactions, including suicide and suicidal attempts.
 

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Pharmaceutical Raw Materials Sulbutiamine For Nootropics Function 3286-46-2

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Pharmaceutical Raw Materials Sulbutiamine For Nootropics Function 3286-46-2
 
Sulbutiamine Basic Info.:
 
Product Name: Sulbutiamine
Molecular Formula: C32H46N8O6S2
CAS Registry Number: 3286-46-2
Synonyms: Arcalion;Bisibutiamine;[4-[(4-Amino-2-methylpyrimidin-5-yl)methylformylamino]-3-[2-[(4-amino-2-methylpyrimidin-5-yl)methylformylamino]-5-(2-methylpropanoyloxy)pent-2-en-3-yl]disulfanylpent-3-enyl] 2-methylpropanoate;
EINECS: 221-937-3
Density: 1.268 g/cm3
Boiling Point: 892.5 °C at 760 mmHg
Flash Point: 493.5 °C 
Appearance: White to off-white crystalline powder
 
Sulbutiamine Introduce:
 
Sulbutiamine is the precursor to the compound Thiamine (Vitamin B1). It is a compound similar in effects to Hydergine but stronger. Its original use was to aid in the treatment of Asthenia, which is a condition associated with loss of physical strength (fatigue). Today, Sulbutiamine is increasingly gaining popularity as one of the most effective Nootropics, and is notable for its mood enhancing effects.
 
Sulbutiamine Usage:
 
Sulbutiamine provides its users with a total state of physical well-being as well as serving as an intellectual performance enhancer. Its popularity has soared in recent years and it is commonly used as a mood enhancer which provides relief in the form of alleviating stress and fatigue commonly associated with depression. It facilitates wakefulness, improves cognitive function, speeds up reaction time, decreases anxiety and anxiety related phobias, as well as many other benefits. It results in a feeling of euphoria similar to caffeinated beverages but without the jitteriness or agitation associated with consuming caffeine. However, this is a much stronger product than caffeine and tends to last the entire day as opposed to caffeine which is short-lived.
 
Sulbutiamine is taken by athletes, party-goers, students and those looking to improve over-all health.  It is useful to athletes and individuals wishing to increase their physical stamina and it is known as a reliable fatigue buster. Research also indicates that it has the ability to increase cognition. It increases memory and alertness and this is very appealing to many students studying for exams. As far as party-goers are concerned, Sulbutiamine has a very calming effect, increases stamina, allowing individuals to party all night and also enhances one's sexual prowess.
 
Recommended Dose: 
 
500 to 1000mg a day, preferably with a meal.
 

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Pharmaceutical Raw Materials Taxus Chinensis Extract Paclitaxel For Anticancer 33069-62-4

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Pharmaceutical Raw Materials Vinblastine Sulfate For Antineoplastic 143-67-9

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Pharmaceutical Raw Materials Vinblastine Sulfate For Antineoplastic 143-67-9
 
Vinblastine Sulfate Basic Info.:
 
Product Name: Vinblastine Sulfate
Synonyms: 29060LE;EXAL;NSC49842;Rozevinsulfate;Velban;Velbe;Vincaleukoblastine,Sulfate(1:1)(Salt);Vinblastine Sulfate Salt;
CAS: 143-67-9
MF: C46H60N4O13S
MW: 909.05
EINECS: 205-606-0
Purity: 99.5%
Melting point: 267 °C (dec.)(lit.)
Alpha: -21.7 º (c=2, CH3OH 21 ºC)
Storage temp.: 2-8°C
Solubility: H2O: 10 mg/mL
Water Solubility: >=1 g/100 mL at 24.5 ºC
Standard: USP /EP /BP 
Appearance: White to slightly yellow crystalline powder.
Usage: Antitumor alkaloid isolated from periwinkle, Vinca rosea Linn., Apocynaceae; inhibits microtubule assembly. An antineoplastic.
 
Vinblastine Sulfate Introduction:
 
Mainly used for the treatment of solid tumor. For malignant lymphoma, testicular neoplasm and choriocarcinoma curative effect is better. For lung, breast, ovarian, skin cancer, renal mother cell tumor and monocytes leukaemia also have certain curative effect.
Pharmacology: Vinblastine Vinca plants for the oleander extract has anti-cancer activity of an alkaloid. Major inhibition of tubulin polymerization, preventing the formation of spindle microtubules, so stop in MID-mitosis. Role in the cell membrane can also interfere with membrane transport of amino acids, protein synthesis was inhibited, also inhibited RNA synthesis.
 
Vinblastine Sulfate Function:
 
1. Mainly used in the treatment of Hodgkin's disease, lymphatic reticulum cell sarcoma, chorionic carcinoma, testicular tumor. Is also effective for other malignant lymphoma.
2. For acute leukemia, mononuclear cell leukemia, lung cancer, breast cancer, ovarian cancer, kidney tumor, oral cancer, malignant melanoma, skin cancer have certain curative effect.
3. Treatment of idiopathic thrombocytopenic purpura.
4. Treatment of rheumatoid arthritis.
 

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Pharmaceutical Safe Organic Solvents Grape Seed Oil For Cooking Cosmetics CAS 85594-37-2

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Pharmaceutical Safe Organic Solvents Grape Seed Oil For Cooking Cosmetics CAS 85594-37-2
 
Grape Seed Oil Basic Info.:
 
Product Name: Grape seed oil
Synonyms: Grapeseed Oil; Oils, grape; Grape stem extract; VITIS VINIFERA (GRAPE) SEED OIL; Traubenkernoel; Grape seed oil;
CAS No.: 85594-37-2
Purity: 99%
Appearance: Pale yellow liquid
Standard: Enterprise Standard
Packing: 200KG/Drum or as per your requirements
Application: Natural Plant Extract; Flavors & Fragrances
 
Grape Seed Oil Description:
 
Appearance: pale green to pale yellow oily liquid
Relative Density: (20 °C) 0.915 ~ 0.925
Refractive index: (20 °C) 1.4700 ~ 1.4750
Linoleic acid: (%) 70 ~ 76
 
Grape Seed Oil Application:
 
1. Grape seed through the most advanced cold pressing method and refined, is one of the very popular in the base oil and the effect is outstanding varieties. Grape seed oil is a natural non-toxic properties, so children, pregnant women, the elderly and athletes are applicable.
2. Atioxidant, dilute the stain.
3. Endocrine disorders caused by dry skin, reduce melanin, whitening skin, removing chloasma.
4. To stimulate cell division and tissue regeneration, activation of the surface cells, reduce wrinkles, delay aging.
5. Inhibit and remove the body of free radicals, anti-cancer anti allergic effect.
6. Anti prostate cancer, the role of anti liver tumor, but also against damage to the nervous system.
 

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Pharmaceutical Trenbolone Steroids Parabolan Trenbolone Enanthate For Weight Loss 10161-33-8

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Pharmaceutical Trenbolone Steroids Parabolan Trenbolone Enanthate For Weight Loss 10161-33-8
 
Trenbolone Enanthate Basic Info.
 
Product Name: Trenbolone Enanthate
Alias: Trenbolone Enanthate;Parabolan;Tren E;10161-33-8;Primobolan-depot;Primobolan-depot
CAS No.: 10161-33-8
Molecular Formula: C25H34O3
Molecular weight: 382.54
Assay: 99.02%
Appearance: pale yellow or yellow crystalline powder
Usage: Trenbolone Enanthate is only available from underground labs and was not designed for human consumption, although it is considered to be an ideal drug for bodybuilders who want to burn fat and gain muscle, although its long ester makes unwise for professional athletes who undergo testing to use.
 
Trenbolone Enanthate Description:
    
Trenbolone Enanthate also shines is in its ability to greatly preserve lean muscle tissue.When we diet, in-order to lose body fat, not weight but body fat we must be in a caloric deficit; we must burn more calories than we consume. As a result, as the body fights change with a desire to hang onto stored body fat due to its survival nature lean muscle tissue is often sacrificed in-order to meet its energy needs. As we lose more lean muscle tissue, this slows down the metabolic rate, and of course, it makes the physique look worse; Trenbolone Enanthate will prevent this. Of course, it gets even better; through its traits, Trenbolone Enanthate will provide the ultimate in visual conditioning effects.
 
Trenbolone Enanthate is a steroid that will greatly increase muscular endurance, more work can be done and you will not tire out as fast and it will also play an important role in recovery and healing.
 
Trenbolone Enanthate Applications:
 
Trenbolone is notably more potent than testosterone, and has an effect that is as much as three times as strong on a milligram for milligram basis. Likewise we can expect to see some level of androgenic side effects with use of this compound. Oily skin, aggressive behavior, acne and hair loss are therefore not uncommon during a cycle with this steroid. The androgenic nature of this drug of course makes it a very risky item for women to use, the chance for virilization symptoms extremely high with such a potent androgen.
 
Trenbolone is also much more potent than testosterone at suppressing endogenous androgen production. This makes clear the fact that estrogen is not the only culprit with negative feedback inhibition, as here there is no buildup of this hormone to report here. There is however some activity as a progestin inherent in this compound, as trenbolone is a 19-nortestosterone (nandrolone) derivative (a trait characteristic of these compounds).
 

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Phenacetin 62-44-2 99%min

Phenacetin 62-44-2
 
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Other Names: Acetophenelidin
 
Category: APIs, pharmaceutical chemicals, materials; antipyretic
 
Quality standard: USP/BP6
 
Assay: 99.0%min
 
Appearance: White crystalline powder
 
Packing: 25kg cardboard drum
 
Application: Antipyretic Analgesics and NSAIDs
 
Place of Origin: China (Mainland)
 
Density: 1.099g/cm3
 
Melting point: 133-138℃
 
Boiling point: 355.1°C at 760 mmHg
 
Refractive index: 1.548
 
Flash point: 168.5°C
 
CAS: 62-44-2
 
EINECS: 200-533-0
 
Molecular Formula: C10H13NO2
 
Molecular Weight: 179.2157
 
 
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Phenacetin Pharmaceutical Intermediates BP Grade Antipyretic Analgesic 62-44-2

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Phenacetin Pharmaceutical Intermediates BP Grade Antipyretic Analgesic 62-44-2
 
1. Phenacetin Quick Detail:
 
Product Name: Phenacetin
CAS: 62-44-2
EINECS Number: 200-533-0
Formula: C10H13NO2
MW: 179.2157
Density: 1.099g / cm3
Melting point: 133-138 °C
Boiling point: 355.1 °C at 760 mmHg
Flash Point: 168.5 °C
Water-soluble: 0.076 g / 100 mL
Vapor Pressure: 3.21E-05mmHg at 25 °C
Uses: Anti-inflammatory drugs
Assay: 99%
Appearance: White or almost white crystalline powder
 
2. Phenacetin Descriptions:
 
Phenacetin is a pain-relieving and fever-reducing drug, widely used from its introduction in 1887 until banned in the US by the FDA in 1983. Its use has declined because of its adverse effects, which include increased risk of certain cancers and kidney damage. It is metabolized into paracetamol, which replaced it in some over-the-counter medications following the ban on phenacetin.
 
3. Applications of Phenacetin:
 
Phenacetin was widely used until the third quarter of the twentieth century, often in the form of an "A.P.C." or aspirin-phenacetin-caffeine compound analgesic, as a remedy for fever and pain. An early formulation (1919) was Vincent's APC in Australia. However the U.S. Food and Drug Administration ordered the withdrawal of drugs containing phenacetin in November 1983, owing to its carcinogenic and kidney-damaging properties (Federal Register of October 5, 1983 (48 FR 45466)).
 
It was also banned in India.As a result some branded, previously phenacetin-based preparations continued to be sold, but with the phenacetin replaced by safer alternatives. A popular brand of phenacetin was Roche's Saridon, which was reformulated in 1983 to contain propyphenazone, paracetamol and caffeine. Coricidin was also reformulated without phenacetin. Paracetamol is a metabolite of phenacetin with similar analgesic and antipyretic effects, but the new formulation has not been found to have phenacetin's carcinogenicity.
 
Phenacetin is now being used as a cutting agent to adulterate cocaine in the UK and Canada, owing to the similar physical features of the two drugs.Due to low cost phenacetin is used for research into the physical and refractive properties of crystals. It is an ideal compound for this type of research.
 

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Phenylcarbinol For Injectable Steroids Hormone Organic Solvent Benzyl Alcoho 100-51-6

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Phenylcarbinol For Injectable Steroids Hormone Organic Solvent Benzyl Alcoho 100-51-6
 
Benzyl Alcohol Basic Info.:
 
Product Name: Benzyl Alcohol
Purity : 99.0%
CAS: 100-51-6
EINECS: 202-859-9
MF: C7H8O
MW: 108.14
Melting point: -15 ºC
Boiling point: 205 ºC
Refractive index: 1.538-1.541
Flash point: 93 ºC
Water solubility: 4.29 g/100 mL (20 ºC)
Chemical Properties: Colourless oily liquid
Appearance:Colorless clear oily liquid with acetone-like odor
Product Categories: Pharmaceutical Intermediates;Heterocycles;Miscellaneous Reagents.
Used for carpet degreaser; crater cleaning agent; silicone solvent stabilizer; benzyl ester or ether intermediate.
 
Benzyl Alcohol Description:
 
Benzyl alcohol is an aromatic alcohol with the formula C6H5CH2OH. The benzyl group is often abbreviated "Bn" (not to be confused with "Bz" which is used for benzoyl), thus benzyl alcohol is denoted as BnOH. Benzyl alcohol is a colorless liquid with a mild pleasant aromatic odor. It is a useful solvent due to its polarity, low toxicity, and low vapor pressure. Benzyl alcohol is partially soluble in water (4 g/100 mL) and completely miscible in alcohols and diethyl ether.
 
Benzyl alcohol is produced naturally by many plants and is commonly found in fruits and teas. It is also found in a variety of essential oils including jasmine, hyacinth, and ylang-ylang.It is also one of the chemical compounds found in castoreum. This compound is gathered from the beaver plant food.
Benzyl alcohol has nearly the same refraction index of quartz and wool fibre. If a clear quartz object is immersed in benzyl alcohol, it becomes almost invisible. This has been used as a method to non-destructively recognize if an object is made of true quartz or not (see crystal skull). Similarly, white wool immersed in benzyl alcohol also becomes almost invisible clearly revealing contaminants such as dark and medullated fibres and vegetable matter
 
Benzyl alcohol is only a mild acute toxin with an LD50 of 1.2 g/kg in rats. It oxidizes rapidly in healthy individuals to benzoic acid, conjugated with glycine in the liver, and excreted as hippuric acid. Very high concentrations can result in toxic effects including respiratory failure, vasodilation, hypotension, convulsions, and paralysis.
 
Benzyl alcohol is toxic to neonates, it is associated with the gasping syndrome.Benzyl alcohol has been reported to cause skin allergy.Benzyl alcohol is severely toxic and highly irritating to the eye.Pure benzyl alcohol produces corneal necrosis.Benzyl alcohol is not considered to be a carcinogen and no data are available regarding teratogenic or reproductive effects.
 
Benzyl Alcohol Application:
 
1. Benzyl alcohol is a good middle boiling point solvent. The main applications:paint solvent; ink solvent; plexiglass solvent; photographic developing agent; PVC stabilizer; medicine, synthetic resin solvent; ointment or liquid medicine; solvent for meat products stamp-pad ink and ball-point pen oil. carpet degreaser; crater cleaning agent; silicone solvent stabilizer; benzyl ester or ether intermediate.
2. Benzyl alcohol is a kind of very useful perfume fixative. It is an indispensable spice when jasmine, tuberose or ylang is mixed, and used to compound soap and daily cosmetics. Benzyl alcohol is used as a general solvent for inks, paints, lacquers, and epoxy resin coatings. It is also a precursor to a variety of esters, used in the soap, perfume, and flavor industries. It is also used as a photographic developer.
 

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Phosphoramidon LAB GRADE

Creative Peptides is specialized in the process development and the manufacturing of bioactive peptides. We are dedicated to offering custom peptide synthesis, process development, GMP manufacturing as well as catalog products for customers in industry and research area. Visit https://www.creative-peptides.com/product/phosphoramidon-item-r0805-34607.html for more information.

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