Pharmaceutical raw materials used in synthesizing new medications

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RPL8 protein (31-41) LAB GRADE 97%

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Rabenosyn-5 (541-552) LAB GRADE 97%

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Rabies Virus Glycoprotein (RVG) LAB GRADE 97%

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Rac1 Inhibitor F56, control peptide LAB GRADE

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Raloxifene Hydrochloride Anti Estrogen Supplements 82640-04-8 Raloxifene HCL Anti Cancer Steroid

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Raloxifene Hydrochloride Anti Estrogen Supplements 82640-04-8 Raloxifene HCL Anti Cancer Steroid
 
Raloxifene HCL Basic Info.:
 
Product Name: Raloxifene HCL (Raloxifene Hydrochloride)
Synonyms: Raloxifene HCL;Raloxifene hydrochloride;Ly156758;Keoxifene;Keoxifene hydrochloride;Ly 139481;Akos 92138;
CAS: 82640-04-8 
MF: C28H28ClNO4S 
MW: 510.04 
Assay:99%
Standard:USP32
Chemical Properties: Light-Yellow Solid 
Usage: amino acid, nutrient. A nonsteroidal, selective estrogen receptor modulator (SERM). Antiosteoporotic. 
Packing: 1kg/foil bag or as required.
 
Raloxifene HCL Description:
 
Raloxifene hydrochloride (HCl) has the empirical formula C28H27NO4SHCl, which corresponds to a molecular weight of 510.05 g/mol. Raloxifene HCl is an off-white to pale-yellow solid that is slightly soluble in water.SERMs mimic estrogen in some tissues and have anti-estrogen activity in others. Other SERMs, such as Pfizer's lasofoxifene and Wyeth's bazedoxifene are in the later development phases.
 
Evista (Raloxifene Hydrochloride) is an estrogen agonist/antagonist, referred to as a selective estrogen receptor modulator (SERM) and belongs to the benzothiophene class of compounds. The biological actions of Raloxifene are largely mediated through binding to estrogen receptors. This binding results in activation of estrogenic pathways in some tissues (Agonism) and and the blockade of estrogenic pathways in other tissues (Antagonism).
 
Raloxifene HCL Usage:
 
Evista is specifically approved for the treatment and prevention of osteoporosis in postmenopausal women, the reduction in risk of invasive breast cancer in postmenopausal women with osteoporosis and the reduction in risk of invasive breast cancer in postmenopausal women at high risk of invasive breast cancer. Evista is supplied as a 60 mg tablet designed for oral administration. The recommended initial dose of the drug is one 60 mg tablet daily, which may be administered any time of day without regard to meals.
 

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Ras-related protein Rab-27A (178-186) LAB GRADE 97%

Creative peptides is specialized in the process development and the manufacturing of bioactive peptides. We offer custom peptide synthesis, process development, GMP manufacturing as well as catalog products. We supply Ras-related protein Rab-27A (178-186).http://www.creative-peptides.com/product/ras-related-protein-rab-27a-item-ta-072-2986.html

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Ras-related protein Rab-38 (50-58) LAB GRADE 97%

Creative peptides is specialized in the process development and the manufacturing of bioactive peptides. We offer custom peptide synthesis, process development, GMP manufacturing as well as catalog products. We supply Ras-related protein Rab-38 (50-58).http://www.creative-peptides.com/product/ras-related-protein-rab-item-ta-286-17589.html

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Raw Material Telmisartan For Anti-cancer Agent CAS 144701-48-4

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Raw Material Telmisartan For Anti-cancer Agent CAS 144701-48-4
 
Telmisartan Basic Info.:
 
Product Name: Telmisartan
CAS: 144701-48-4
MF: C33H30N4O2
MW: 514.63
MP: 261-263°C
Purity: 99%
Density: 1.16
Storage temp.: Hygroscopic, -20°C Freezer, Under Inert Atmosphere
Solubility DMSO: >5 mg/mL at 60 °C
Water Solubility: insoluble
Chemical Properties: White or off white crystalline powder
Usage: An angiotensin II receptor antagonist.API.
 
Medical Use Of Telmisartan:
 
Telmisartan is a new antihypertensive drugs, a specific angiotensin Ⅱ receptor (AT1 type) antagonist. Telmisartan alternative angiotensin Ⅱ receptor binding with high affinity AT1 receptor subtype. Telmisartan AT1 receptor sites in any part of agonist effects of telmisartan in combination with selective AT1 receptors, the binding lasting effect. Buck stability does not cause coughing.
 

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Raw Medical Material Powder Priligy / Dapoxetine 119356-77-3

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Raw Medical Material Powder Priligy / Dapoxetine 119356-77-3
 
Dapoxetine Basic Info:
 
Product Name: Dapoxetine 
Synonyms: Priligy;Dapoxetine;Dapoxetine hydrochloride;Dapoxetine base;D-Dapoxetine HCL
CAS: 119356-77-3
MF: C21H23NO.ClH
MW: 341.88
EINECS: N/A
Purity: 99%
Appearance: White powder, odorless, slightly sweet, soluble in water and alcohol.
Product Categories: Erectile Dysfunction;API;Dapoxetine hydrochloride
  
Dapoxetine Description:
 
Premature ejaculation (PE) is the most common male sexual dysfunction. Dapoxetine hydrochloride, belonging to a class of drugs known as selective serotonin reuptake inhibitors or, was the first drug originally approved for the on-demand treatment of men with PE. We aimed to compare the intravaginal ejaculatory latency time (IELT), patient-reported global impression of change (PGIC), and adverse effect (AE) incidence associated with the use of dapoxetine (30 mg and 60 mg) versus placebo, and evaluate the differences in administering 60 mg versus 30 mg as on-demand medical oral therapy for the treatment of PE via a literature review and meta-analysis. Relevant randomized controlled trials (RCTs) were identified from PubMed, EMBASE, and Cochrane Central Register of Controlled Trials (Cochrane Library) databases. Ultimately, a total of seven RCTs with 8039 patients were included. Our meta-analysis demonstrated that dapoxetine (in the 30 mg and 60 mg subgroup) resulted in significantly higher IELT, PGIC, and AE incidence relative to the placebo, with higher proportions observed for 60 mg versus 30 mg of dapoxetine administration. The most common AEs were mild and tolerable. We conclude that dapoxetine (particularly the 60 mg dosage) may be considered a safe and effective drug for patients with PE.
 
Dapoxetine Application:
 
Dapoxetine hydrochloride is a drug that is used to treat premature ejaculation in men. It is available by prescription and is taken orally, prior to sexual intercourse. The drug belongs to the class called serotonin reuptake inhibitors (SSRIs), which have mainly been used to treat depression.
 
Sexual dysfunction, including premature ejaculation, is an extremely common condition worldwide. The cause of premature ejaculation has not been fully elucidated, but may include both psychological and physiological factors. Premature ejaculation refers to a short ejaculation time, which can affect the satisfaction of both partners during sexual intercourse.
 

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Raw Pharmaceutical Powder Capecitabine For Antineoplastic Function CAS 154361-50-9

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Raw Pharmaceutical Powder Capecitabine For Antineoplastic Function CAS 154361-50-9 
 
Capecitabine Basic Info.:
 
Product name: Capecitabine
Synonym: 5-Deoxy-5-fluoro-N-[(pentyloxy)carbonyl]cytidine
Assay:99%
Molecular formula:C15H22FN3O6 
Molecular weight: 359.358
CAS number: 154361-50-9
Appearance: White or almost white crystalline powder.
Pharmacology: Capecitabine combine with Docetaxel treatment includes failure of anthracycline chemotherapy in metastatic breast cancer and the The transfer of single-agent first-line treatment of colorectal cancer
 
Capecitabine Application:
 
Capecitabine is a chemotherapy drug| that usually given to treat cancer of the colon, rectum|, breast|, stomach|, pancreas|and gullet| (oesophagus).
Capecitabine is a prodrug, that is enzymatically converted to 5-fluorouracil in the tumor, where it inhibits DNA synthesis and slows growth of tumor tissue. The activation of capecitabine follows a pathway with three enzymatic steps and two intermediary metabolites, 5'-deoxy-5-fluorocytidine (5'-DFCR) and 5'-deoxy-5-fluorouridine (5'-DFUR), to form 5-fluorouracil.
 

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