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Phytochemical Medical Drug Scopolamine Hydrobromide 114-49-8

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Phytochemical Medical Drug Scopolamine Hydrobromide 114-49-8 
 
Scopolamine Hydrobromide Basic Info.:
 
Product Name: Scopolamine Hydrobromide
Synonyms: Scopolamine Hbr;(-)-Scopolamine Hydrobromide;Scopolamine Hydrobromide;Scopoloamine Hydrobromide;Scopine Tropate Hydrobromide;
CAS: 114-49-8
MF: C17H22BrNO4
MW: 384.26
EINECS: 204-050-6
Melting point: 195-199 °C (dry matter)(lit.)
Storage temp.: Store at RT
solubility: H2O: 50 mg/mL
Chemical Properties: Off-White Solid
Usage: An acetylcholine antagonist. Used in treatment of motion sickness; antiemetic; antispasmodic; mydriatic; preanesthetic medicant.
Product Categories: Alkaloids;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Isotope Labeled Compounds;Acetylcholine receptor;API;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Inhibitorsthromboxane, leukotriene) synthesis and release to relieve redness, swelling, heat, pain and other symptoms.
 
Scopolamine Hydrobromide Description:
 
Hyoscine hydrobromide, also known as scopolamine ,hyoscine, levo-duboisine, or burundanga,and sold as Scopoderm, is a tropane alkaloid drug with muscarinic antagonist effects. It is among the secondary metabolites of plants from Solanaceae (nightshade) family of plants, such as henbane, jimson weed, angel's trumpets, and corkwood .Scopolamine exerts its effects by acting as a competitive antagonist at muscarinic acetylcholine receptors; it is thus classified as an anticholinergic, antimuscarinic drug. Although it is usually referred to as a nonspecific antagonist,there is indirect evidence for m1-receptor subtype specificity.
 
Scopolamine Hydrobromide Application: 
 
1. Postoperative nausea and vomiting and sea sickness, leading to its use by scuba divers.
2. Motion sickness (where it is often applied as a transdermal patch behind the ear).
3. Gastrointestinal spasms.
4. Renal or biliary spasms.
5. Aid in gastrointestinal radiology and endoscopy.
6. Irritable bowel syndrome.
7. Clozapine-induced hypersalivation (drooling).
8. Bowel colic.
9. Eye inflammation.
 

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