Pharmaceutical raw materials used in synthesizing new medications

Glyceraldehyde-3-phosphate dehydrogenase (219-230) LAB GRADE 97%

Creative peptides is specialized in the process development and the manufacturing of bioactive peptides. We offer custom peptide synthesis, process development, GMP manufacturing as well as catalog products. We supply Glyceraldehyde-3-phosphate dehydrogenase (219-230).http://www.creative-peptides.com/product/glyceraldehyde-phosphate-dehydrogenase-item-ta-146-8670.html

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High Quality Anti-Estrogen Steroids Raloxifene HCl 82640-04-8

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High Quality Anti-Estrogen Steroids Raloxifene HCl 82640-04-8

Raloxifene HCL Basic Info.:

Product Name: Raloxifene Hydrochloride

Synonyms: Raloxifene HCL;Raloxifene Hydrochloride;Ly156758;Piperidin;Keoxifene;Keoxifene Hydrochloride;Ly 139481;AKOS 92138

CAS: 82640-04-8

MF: C28H28ClNO4S

MW: 510.04

Melting Point: 250-253°C

Storage Temp.: -20°C Freezer

Solubility DMSO: 28 mg/mL, soluble

Chemical Properties: Light-Yellow Solid

Assay: 99%

Grade: Pharmaceutical Grade

Product Categories: Active Pharmaceutical Ingredients;Raloxifene;Intracellular receptor;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds;Pharmaceutical intermediate;API;Inhibitors;antifungal

Usage: amino acid, nutrient, Labeled Raloxifene, intended for use as an internal standard for the quantification of Raloxifene by GC- or LC-mass spectrometry.A nonsteroidal, selective estrogen receptor modulator (SERM). Antiosteoporotic.

Product Description:

Raloxifene HCL(marketed as Evista) is an oral selective estrogen receptor modulator (SERM) that has estrogenic actions on bone and anti-estrogenic actions on the uterus and breast. It is used in the prevention of osteoporosis in postmenopausal women and to reduce the risk of invasive breast cancer in postmenopausal women with osteoporosis and in postmenopausal women at high risk for invasive breast cancer.

This drug is different from hormones (including estrogens and progestins). It works by acting like estrogen (as a selective estrogen receptor modulator or SERM) in some parts of the body. Raloxifene HCL helps to preserve bone mass, but it does not affect the breast and uterus like estrogen or relieve symptoms of menopause such as hot flashes.

Raloxifene HCL is indicated for the treatment and prevention of osteoporosis in postmenopausal women. It is also used for reduction of risk and treatment of invasive breast cancer, and it also reduces breast density.For either osteoporosis treatment or prevention, supplemental calcium and/or vitamin D should be added to the diet if daily intake is inadequate.

Raloxifene HCL is used to prevent and treat bone loss (osteoporosis) in women after menopause. Maintaining strong bones by slowing bone loss helps to reduce the risk of fractures.

Raloxifene HCL may also lower the chance of getting a certain type of breast cancer (invasive) in women after menopause.

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Injectable Steroid Oil Liquid Mass 500 Mg/Ml For Body Building

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Injectable Steroid Oil Liquid Mass 500 Mg/Ml For Body Building

Mass 500 Basic Info.:

Product Name: Mass 500

1ml Mass 500 contains:

200mg Testosterone Decanoate,

150mg Boldenone Undecylenate,

150mg Nandrolone Decanoate

Product Description Of Mass 500:

Testosterone Decanoate:

Testosterone decanoate is a steroid hormone from the androgen and is found in mammalsand other vertebrates, testosterone decanoate is primarily secreted in the tests of mailsand the ovaries of female, although small amount are also secreted by the adrenal glands,testosterone decanoate is the principle male sex hormone and an anabolic steroid.Testosterone decanoate plays a key role in the development of male reproductive tissue,such as the testis and prostates. In addition, testosterone decanoate is essential for health and well-being as well as the prevention of osteoporosis, testosterone decanoateis conserved through most vertebrates, although fish make a slightly difference from called 11-ketotestosterone.

Boldenone Undecylenate:

Boldenone Undeclynate is an anabolic steroid developed for veterinary use, mostly for treatment of horses. In the US it is not indicated for use in humans and is only available through veterinary clinic. The activity of boldenone is mainly anabolic, with a low androgenic potency.

Boldenone will increase nitrogen retention, protein synthesis, increases appetite and stimulates the release of erythropoietin in the kidneys.

Nandrolone Decanoate:

Nandrolone decanoate is a popular steroid which is structurally similar to testosterone, minus a carbon atom at the 19th position. This creates a steroid that exhibits less androgenic properties compared to that of Testosterone, resulting in the conversion to a weaker metabolite- dihydronandrolone, not DHT. Androgenic related side effects are still possible, but are likely to be of a less occurrence compared to that of the likes of testosterone. The compound is usually referred to as 'deca' as deca-durabolin was the brand name by Organon for their nandrolone decanoate.

Mass 500 Application:

We only use USP/BP standard steroid powders, oil and solvents to make steroid injections. only offer semi-finished steroid injections. You just need to buy some syringe filters To filter it before injection. Heating semi-finished steroid injections to 20ºC will make Filtering smoother.

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LDLR-fucosyltransferaseAS fusion protein (312-320) LAB GRADE 97%

Creative peptides is specialized in the process development and the manufacturing of bioactive peptides. We offer custom peptide synthesis, process development, GMP manufacturing as well as catalog products. We supply LDLR-fucosyltransferaseAS fusion protein (312-320).http://www.creative-peptides.com/product/ldlr-fucosyltransferaseas-fusion-protein-item-ta-212-14597.html

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LDLR-fucosyltransferaseAS fusion protein (315-323) LAB GRADE 97%

Creative peptides is specialized in the process development and the manufacturing of bioactive peptides. We offer custom peptide synthesis, process development, GMP manufacturing as well as catalog products. We supply LDLR-fucosyltransferaseAS fusion protein (315-323).http://www.creative-peptides.com/product/ldlr-fucosyltransferaseas-fusion-protein-item-ta-211-14387.html

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Lidocaine HCL 73-78-9 Natural Procaine Lidocaine Hydrochloride

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Lidocaine HCL 73-78-9 Natural Procaine Lidocaine Hydrochloride

Lidocaine HCL Basic Info.:

Product name: Lidocaine HCl

Alias: Lidocaine Hydrochloride

CAS No.: 73-78-9

Molecular Formula: C14H23ClN2O

Molecular Weight: 270.8

EINECS: 200-803-8

Appearance: White crystalline powder

Melting point: 80-82°C

Usage: To enhance the growing of man genitals.

Product Description Of Lidocaine HCL:

Lidocaine, as a local anesthetic, is characterized by a rapid onset of action and intermediate duration of efficacy. Therefore, lidocaine is suitable for infiltration, block and surface anesthesia. Longer-acting substances such as bupivacaine are sometimes given preference for subdural and epidural anesthesias. Lidocaine, on the other hand, has the advantage of a rapid onset of action. It can stop Epinephrine vasoconstricts arteries form bleeding, and it can also delays the resorption of lidocaine, almost doubling the duration of anaesthesia. For surface anesthesia several formulations are available that can be used e. G. For endoscopies, before intubations etc. Buffering the pH of lidocaine makes local freezing less painful. Lidocaine drops can be used on the eyes for short ophthalmic procedures.

Lidocaine HCL Applications:

Topical lidocaine has been shown in some patients to relieve the pain of postherpetic neuralgia (a complication of shingles), though there is not enough study evidence to recommend it as a first-line treatment. IV lidocaine also has uses as a temporary fix for tinnitus. Although not completely curing the disorder, it has been shown to reduce the effects by around two thirds.

Lidocaine hydrochloride injection administered intravenously or intramuscularly, is specifically indicated in the acute management of ventricular arrhythmias such as those occurring in relation to acute myocardial infarction, or during cardiac manipulation, such as cardiac surgery.

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Male Enhancement 4-Androstenedione 63-05-8 For Muscle Building

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Male Enhancement 4-Androstenedione 63-05-8 For Muscle Building

Androstenedione Basic Info.

Product Name: Androstenedione

Synonyms: 4-Androstenedione;4AD;3,17-Dioxoandrost-4-Ene;delta-(sup4)-Androsten-3,17-dione;delta(Sup4)-Androstene-3,17-dione;delta4-androsten-3,17-dione;delta-4-androstenedione;SKF 2170;skf2170;4-AD

CAS: 63-05-8

MF: C19H26O2

MW: 286.41

EINECS: 200-554-5

Purity: 98.88%

Manufacturer: Kafen

Characters: Near white crystalline powder, soluble in ethanol, insoluble in water

Androstenedione Applications:

Testo-ster-one precursor and metabolite with androgenic activity. Controlled substance (anabolic steroid); Simplified hormone drugs, from the testis or urine extracted with the role of a male hormone steroids, norethisterone, testosterone propionate in the middle body, is widely used in small rheumatoid arthritis, diuretic, and a variety of contraceptive to control infectious inflammation.

Androstenedione Description:

4-Androstenedione can be synthesized in one of two ways. The primary pathway involves conversion of 17-hydroxypregnenolone to dehydroepiandrosterone by way of 17,20-lyase, with subsequent conversion of dehydroepiandrosterone to 4-Androstenedione via the enzyme 3-β-hydroxysteroid dehydrogenase. The secondary pathway involves conversion of 17-hydroxyprogesterone, most often a precursor to cortisol, to 4-androstenedione directly by way of 17,20-lyase. Thus, 17,20-lyase is required for the synthesis of 4-androstenedione, whether immediately or one step removed.

The production of adrenal 4-Androstenedione is governed by ACTH, whereas production of gonadal 4-Androstenedione is under control by gonadotropins. In premenopausal women, the adrenal glands and ovaries each produce about half of the total 4-androstenedione(about 3 mg/day). After menopause, 4-androstenedione production is about halved, due primarily to the reduction of the steroid secreted by the ovary. Nevertheless, 4-androstenedione is the principal steroid produced by the postmenopausal.

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Manufacturer Terlipressin Acetate With High Quality 14636-12-5

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Manufacturer Terlipressin Acetate With High Quality 14636-12-5

Terlipressin Acetate Basic Info.:

Product Name: Terlipressin Acetate

Synonyms: Terlipressin;Terlipressin Acetate;Terilipressin;

CAS: 14636-12-5

MF: C52H74N16O15S2

MW: 1227.37

EINECS: 238-680-8

Product Categories: Amino Acid Derivatives;Peptide;hormones

Usage: Terlipressin is an analogue of vasopressin used as a vasoactive drug in the management of hypotension. Terlipressin is used norepinephrine-resistant septic shock and hepatorenal syndrome. Terlipressin is also used in the treatment of acute variceal bleeding.

Terlipressin Acetate Pharmacological Effects:

Terlipressin is a novel long-acting synthetic vasopressin reagent,its chemical name is three glycyl lysine vasopressin, it is a prodrug, itself has no activity ,in vivo , it removes three glycyl residues in its N-terminus by aminopeptidase, and slowly "releases" the active lysine vasopressin. It is this "slow release" mechanism that makes it maintain the smooth muscle contraction up to 10 hours after a single administration, whereas the same dose of vasopressin, it can maintain its activity for 20-40 minutes. On the other hand,because of the slow digestion, lysine vasopressin in the circulation cannot reach toxic levels, and usage of terlipressin is safer.

Pharmacological effect of terlipressin is splanchnic vascular smooth muscle contraction, and reduction of visceral blood flow (such as reducing blood flow in the mesentery, spleen, uterus, etc.), thereby reducing portal vein blood flow,and reducing portal pressure, on the other hand it may also reduce plasma renin concentration, thereby increasing the renal blood flow in patients with hepatorenal syndrome, to improve kidney function, and increase urine output. Terlipressin is currently the only drug which is able to increase mortality in patients with esophageal varices bleeding , it is previously mainly used in clinical for the treatment of variceal bleeding, in addition,terlipressin now has also been successfully used for liver and kidney integrated syndrome and refractory shock, it is also likely to play a useful role in the cardiopulmonary resuscitation . Compared with vasopressin, it has a lasting effect, and it does not cause dangerous complications, including promoting fibrinolysis and severe complications in the cardiovascular systems, and the use of it is simple (available intravenous injection), it is more suitable for rescue and treatment of emergent and critical patients.

Terlipressin Acetate Mechanism of Action:

Terlipressin, a synthetic triglycyl-lysine derivative of vasopressin, is a inactive prodrug. It has pressor and antidiuretic effects. Following IV injection, lysine vasopressin are released following the enzymatic cleavage of 3 glycyl moieties.

Duration: 4-6 hr.

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N,5-Bis(4-chlorophenyl)-3,5-dihydro-3-imino-2-phenazinamine 95%

Name		N,5-Bis(4-chlorophenyl)-3,5-dihydro-3-imino-2-phenazinamine
Synonyms		B 628; B 628 (pharmaceutical)

Molecular Structure

Molecular Formula		C24H16Cl2N4
Molecular Weight		431.32
CAS Registry Number		102262-55-5

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Raw Material Telmisartan For Anti-cancer Agent CAS 144701-48-4

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Raw Material Telmisartan For Anti-cancer Agent CAS 144701-48-4

Telmisartan Basic Info.:

Product Name: Telmisartan

CAS: 144701-48-4

MF: C33H30N4O2

MW: 514.63

MP: 261-263°C

Purity: 99%

Density: 1.16

Storage temp.: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

Solubility DMSO: >5 mg/mL at 60 °C

Water Solubility: insoluble

Chemical Properties: White or off white crystalline powder

Usage: An angiotensin II receptor antagonist.API.

Medical Use Of Telmisartan:

Telmisartan is a new antihypertensive drugs, a specific angiotensin Ⅱ receptor (AT1 type) antagonist. Telmisartan alternative angiotensin Ⅱ receptor binding with high affinity AT1 receptor subtype. Telmisartan AT1 receptor sites in any part of agonist effects of telmisartan in combination with selective AT1 receptors, the binding lasting effect. Buck stability does not cause coughing.

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