Pharmaceutical raw materials used in synthesizing new medications

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TGF-beta receptor type-2 (131-139) LAB GRADE 97%

Creative peptides is specialized in the process development and the manufacturing of bioactive peptides. We offer custom peptide synthesis, process development, GMP manufacturing as well as catalog products. We supply TGF-beta receptor type-2 (131-139).http://www.creative-peptides.com/product/tgf-beta-receptor-type-item-ta-238-15864.html

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TPA: ovochymase precursor (314-332) LAB GRADE 97%

Creative peptides is specialized in the process development and the manufacturing of bioactive peptides. We offer custom peptide synthesis, process development, GMP manufacturing as well as catalog products. We supply TPA: ovochymase precursor (314-332).http://www.creative-peptides.com/product/tpa-ovochymase-precursor-item-ta-180-12514.html

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TPI HLA-DR1 LAB GRADE 97%

Creative peptides is specialized in the process development and the manufacturing of bioactive peptides. We offer custom peptide synthesis, process development, GMP manufacturing as well as catalog products. We supply TPI HLA-DR1.http://www.creative-peptides.com/product/tpi-hla-dr1-item-ta-031-763.html

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TRX-0237 mesylate LAB GRADE 97%

A second-generation tau protein aggregation inhibitor

http://www.bocsci.com/trx-0237-mesylate-cas-1236208-20-0-item-474113.html

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TRx 0237 LAB GRADE 97%

A second-generation tau protein aggregation inhibitor; Phase Ⅲ

http://www.bocsci.com/trx-0237-cas-613-11-6-item-129376.html

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Tacrolimus FK-506 Pharmaceutical Intermediates Organ Transplant 104987-11-3

Welcome to inquiry!

Email: tony@kafenbio.com

WhatsApp: +8618002259573

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www.pharmhormone.com

 
Tacrolimus FK-506 Pharmaceutical Intermediates Organ Transplant  104987-11-3
 
Tacrolimus Basic info: 
 
Product Name: Tacrolimus
Synonyms: Tacrolimus;Fr900506;Prograf;Tsukubaenolide;FK-506;
CAS: 104987-11-3
MF: C44H69NO12
MW: 804.02
Purity: 99%
Melting Point: 113-115°C
Boiling Point: 871.7 °C at 760 mmHg
Solubility: DMSO: >3 mg/mL
Appearance: White Crystalline Powder
Storage temp.: −20°C
Storage: Store in a cool, dry place. Do not store in direct sunlight. Store in a tightly closed container.
Product Categories: Active Pharmaceutical Ingredients;Immunosuppressant.;Intermediates & Fine Chemicals;Pharmaceuticals;API;Chiral Reagents;Fujimycin, Prograf;antibiotic;Inhibitors.
Usage: FK-506 (Tacrolimus) is a macrolide immunosuppressive drug that is mainly used after allogeneic organ transplant to reduce the activity of the patient's immune system.
 
Tacrolimus Application: 
 
L Immunosuppression following transplantation It has similar immunosuppressive properties to ciclosporin, but is much more potent. Immunosuppression with tacrolimus was associated with a significantly lower rate of acute rejection compared with ciclosporin-based immunosuppression (30.7% vs 46.4%) in one study. Clinical outcome is better with tacrolimus than with ciclosporin during the first year of liver transplantation. Long term outcome has not been improved to the same extent. Tacrolimus is normally prescribed as part of a post-transplant cocktail including steroids, mycophenolate and IL-2 receptor inhibitors. Dosages are titrated to target blood levels. Typical starting doses for once daily tacrolimus are 0.15-0.20 mg/kg body weight.
 
Tacrolimus Interactions:
 
Also like cyclosporin it has a wide range of interactions, including that with grapefruit which increases plasma-tacrolimus concentration. Several of the newer class of antifungals, especially of the azole class (fluconazole, posaconazole) also increase drug levels by competing for degradative enzymes.
 
Ulcerative colitis: 
In recent years, tacrolimus has been used to suppress the inflammation associated with ulcerative colitis, a form of inflammatory bowel disease. Although almost exclusively used in trial cases only, tacrolimus has shown to be significantly effective in the suppression of outbreaks of UC.
 
Tacrolimus Dermatological Use: 
 
As an ointment, tacrolimus is used in the treatment of eczema, in particular atopic dermatitis. It suppresses inflammation in a similar way to steroids, and is equally as effective as a mid-potency steroid. An important advantage of tacrolimus is that, unlike steroids, it does not cause skin thinning (atrophy), or other steroid related side-effects.
 
It is applied on the active lesions until they heal off, but may also be used continuously in low doses (twice a week), and applied to the thinner skin over the face and eyelids[citation needed]. Clinical trials of up to one year have been conducted. Recently it has also been used to treat segmental vitiligo in children, especially in areas on the face.
 

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Tadalafil

Aarambh Life Science is the manufacturer factory of Veterinary and Human APIs in India   Human products producer by Aarambh life science are   Sildenafil Citrate   Avanafil   Vardenafil   Tadalafil   Pirfenidon   Pirfenidone   Guaifenesin   Chlorhexidine   Metformin hcl   Lidocaine   Ketokonazole   Colesevelam HCL . Aarambh Life Science exporter of Human API for Sildenafil Citrate   Avanafil   Vardenafil   Tadalafil   Pirfenidon   Pirfenidone   Guaifenesin   Chlorhexidine   Metformin hcl   Lidocaine   Ketokonazole   Colesevelam HCL are in many countries.

 

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Tartaric Acid USP, BP, EP

Planet Science is a manufacturer of Tartaric Acid Grade - USP, BP EP. We export our material to all countries in the world.

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Tasimelteon Purified >99%

product Name: Tasimelteon

Synonyms: (1R-trans)-N-[[2-(2,3-Dihydro-4-benzofuranyl)cyclopropyl]methyl]propanamide; N-{[(1R,2R)-2-(2,3-dihydro-1-benzofuran-4-yl)cyclopropyl]methyl}propanamide

Molecular Formula: C15H19NO2

Molecular Weight: 245.3169

InChI: InChI=1/C15H19NO2/c1-2-15(17)16-9-10-8-13(10)11-4-3-5-14-12(11)6-7-18-14/h3-5,10,13H,2,6-9H2,1H3,(H,16,17)/t10-,13+/m0/s1

CAS Registry Number: 609799-22-6

Density: 1.146g/cm3

Boiling point: 442.553 deg C at 760 mmHg

Refractive index: 1.564

Flash point: 221.448 deg C

Vapour Pressure: 0mmHg at 25 deg C

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