Pharmaceutical raw materials used in synthesizing new medications

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1-(3, 4-Dichlorophenyl)-2-(1H-Imidazole-1-yl)-Ethanol LAB GRADE 97%

BOC Sciences manufactures thousands of pharmaceutical impurities, degradations, metabolites of active pharmaceutical ingredients, and excipients in accordance with the guidelines and limits described in the international pharmacopeia monographs for many impurities to serve drug development. In particular, BOC Sciences has access to rarely found degradations preparation standards for a number of OTC pharmaceuticals, which enables us to manufacture many degradations with ease; and occasionally we share the standards with our clients all over the world. We provide 1-(3, 4-Dichlorophenyl)-2-(1H-Imidazole-1-yl)-Ethanol. More information please visit the webiste: http://www.bocsci.com/im-ISOCONAZOLE-and-Impurities-list-1244.html

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Ankyrin repeat domain-containing protein 11 (421-433) LAB GRADE 97%

Creative peptides is specialized in the process development and the manufacturing of bioactive peptides. We offer custom peptide synthesis, process development, GMP manufacturing as well as catalog products. We supply Ankyrin repeat domain-containing protein 11 (421-433).http://www.creative-peptides.com/product/ankyrin-repeat-domain-containing-protein-item-ta-132-7496.html

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Baculoviral IAP repeat-containing protein 7 (280-289) LAB GRADE 97%

Creative peptides is specialized in the process development and the manufacturing of bioactive peptides. We offer custom peptide synthesis, process development, GMP manufacturing as well as catalog products. We supply Baculoviral IAP repeat-containing protein 7 (280-289).http://www.creative-peptides.com/product/baculoviral-iap-repeat-containing-protein-item-ta-033-817.html

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Best Price 99.9% Purity Vardenafil Fardenafil Hormone 224785-91-5

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Best Price 99.9% Purity Vardenafil Fardenafil Hormone 224785-91-5
 
Vardenafil Basic Info.:
 
Product Name: Vardenafil
Synonym: Fardenafil; Vardenafil 
CAS No: 224788-91-5
MF: C23H33ClN6O4S
MW: 525.06
Purity: 99%
Half life: 4-5 hours
Appearance: white powder, odorless, taste bitter and astringent soluble in water and alcohol.
Storage: in a cool and dry well-closed container and in ventilated area
  
Vardenafil Description:
 
Vardenafil (INN) is a PDE5 inhibitor used for treating erectile dysfunction. Vardenafil's indications and contra-indications are the same as with other PDE5 inhibitors; it is closely related in function to sildenafil citrate (Viagra) and tadalafil (Cialis). The difference between the vardenafil molecule and sildenafil citrate is a nitrogen atom's position and the change of sildenafil's piperazine ring methyl group to an ethyl group. Tadalafil is structurally different from both sildenafil and vardenafil. Vardenafil's relatively short effective time is comparable to but somewhat longer than sildenafil's.
  
Vardenafil Application:
 
Beyond its indications for erectile dysfunction, vardenafil may be effective in the treatment of premature ejaculation, where it may significantly increase the time from vaginal penetration to ejaculation.
Vardenafil, as with all PDE5 inhibitors, should not be used by men taking nitrate medications, because combining them with vardenafil might provoke potentially life-threatening hypotension (low blood pressure).
Further, Vardenafil causing lengthening of the QT interval. Therefore it should not be taken by men taking other medications that affect the QT interval (such as amiodarone).
 

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Ethyl Oleate CAS 111-62-6 Pharmaceutical Grade Transparent Liquid

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Ethyl Oleate CAS 111-62-6 Pharmaceutical Grade Transparent Liquid
 
Ethyl Oleate Basic Info.:
 
Product Name: Ethyl Oleate
CAS: 111-62-6
Formula: C20H38O2
Molecular Weight: 310.51
Appearance: Clear pale yellow oily liquid
Purity: 99%
Package: 22kg 180kg 900kg/drum
EINECS: 203-889-5
Density: 0.872 g/cm3
Melting Point: - 32 °C(lit. )
Boiling Point: 385.9 °C at 760 mmHg
Flash Point: 91.8 °C
Storage: Kept in cool and dry place away from sunlight.
Usage: It was obtained by the hydrolysis of various animal and vegetable fats and oils.
 
Ethyl Oleate Description:
 
Ethyl oleate is used as a solvent for pharmaceutical drug preparations involving lipophilic substances such as steroids. It also finds use as a lubricant and a plasticizer. Ethyl oleate is regulated as a food additive by the Food and Drug Administration under "Food Additives Permitted for Direct Addition to Food for Human Consumption. Ethyl oleate is a fatty acid ester formed by the condensation of oleic acid and ethanol. It is a colorless to light yellow liquid. Ethyl oleate is produced by the body during ethanol intoxication. Ethyl oleate is used as a solvent for pharmaceutical drug preparations involving lipophilic substances such as steroids. It also finds use as a lubricant and a plasticizer. Ethyl oleate is regulated as a food additive by the Food and Drug Administration under "Food Additives Permitted for Direct Addition to Food for Human Consumption", Ethyl oleate has been identified as a primer pheromone in honeybees.
 
Ethyl oleate is one of the fatty acid ethyl esters (FAEE) that is formed in the body after ingestion of ethanol. There is a growing body of research literature that implicates FAEEs such as ethyl oleate as the toxic mediators of ethanol in the body (pancreas, liver, heart, andbrain) Among the speculations is that ethyl oleate may be thetoxicmediator of alcohol in fetal alcohol syndrome. The oral ingestion of ethyl oleate has been carefully studied and due to rapid degradation in the digestive tract it appears safe for oral ingestion. Ethyl oleate is not currently approved by the U.S. Food and Drug Administration for any injectable use. However, it is used by compounding pharmacies as a vehicle for intramuscular drug delivery, in some cases to prepare the daily doses of progesterone in support of pregnancy. Studies which document the safe use of ethyl oleate in pregnancy for both the mother and the fetus have never been performed.
 
Ethyl Oleate Application:
 
Ethyl Oleate BP/EP is a pharma grade material used in many applications such as pharmaceutical preparations, food, cosmetics and health & beauty applications. Ethyl Oleate can function as solvent, glossing agent and emollient. It is an excellent solvent and good moisturiser. Suitable for skin care, hair care and colour cosmetics.
 

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Factory Sell High Purity Nootropics Powder Phenibut CAS 1078-21-3

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Factory Sell High Purity Nootropics Powder Phenibut CAS 1078-21-3
 
Phenibut Basic information 
 
Product Name: Phenibut ( 4-Amino-3-phenylbutyric acid hydrochloride )
Product Name: 4-Amino-3-phenylbutyric acid hydrochloride
Synonyms: Phenibut;TIMTEC-BB SBB001567;PHENIBUT;4-amino-3-phenylbutanoicacid;4-amino-3-phenyl-butyricaci;beta-(aminomethyl)-benzenepropanoicaci;beta-(aminomethyl)benzenepropanoicacid;beta-(aminomethyl)hydrocinnamicacid;beta-phenyl-gamma-aminobutyrate
CAS: 1078-21-3
MF: C10H14ClNO2
MW: 215.68
EINECS: 214-079-6
Product Categories: Organic acids;Nutritions & Sterides;API;Inhibitors.
 

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NAD-dependent protein deacetylase sirtuin-2 (192-200) LAB GRADE 97%

Creative peptides is specialized in the process development and the manufacturing of bioactive peptides. We offer custom peptide synthesis, process development, GMP manufacturing as well as catalog products. We supply NAD-dependent protein deacetylase sirtuin-2 (192-200).http://www.creative-peptides.com/product/nad-dependent-protein-deacetylase-sirtuin-item-ta-235-15751.html

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Pharmaceutical Grade Raw Material Chitosan CAS 9012-76-4 For Food

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Pharmaceutical Grade Raw Material Chitosan CAS 9012-76-4 For Food
 
Chitosan Basic information
 
Product Name: Chitosan
Synonyms: POLY(BETA-(1,4)-2-AMINO-2-DEOXY-D-GLUCOSE);POLY(BETA-(1,4)-D-GLUCOSAMINE);POLY(D-GLUCOSAMINE);POLY-(1,4-BETA-D-GLUCOPYRANOSAMINE);POLY-[1->4]-BETA-D-GLUCOSAMINE;BETA-(1,4)-2-AMINO-2-DEOXY-D-GLUCOSE;DEACETYLATED CHITIN;CHITOSAN
CAS: 9012-76-4
MF: C6H11NO4X2
MW: 161.16
EINECS: 222-311-2
Storage temp.: room temp
Solubility: dilute aqueous acid (pH <6.5).: soluble
Stability: Stable. Incompatible with strong oxidizing agents.
Chemical Properties: faintly beige solid  (Coarse ground flakes and powder)
Product Categories: Miscellaneous Natural Products;Biochemistry;Polysaccharides;Sugars;Nutritional Supplements;Dextrins、Sugar & Carbohydrates;Activity Other;Carbohydrate adjuvants;Carbohydrates A-C;Chitosan and Chitin;Activity;and Substrates;Biochemicals and Reagents;Carbohydrates;Carbohydrates A to Z;Cell Culture;Chitosan;Enzyme Substrates;Enzymes;Inhibitors;Materials Science;Natural Polymers;Polymer Science;Polymers;Polysaccharide;Vaccine Adjuvants;Vaccine Production;Oligosaccharide,Biostimulate
Usage: Claimed to have the ability to retain fats and cholesterol in the stomach.
Properties: This product is non-toxic, odorless, off-white or slight yellow powder, and soluble in acid, insoluble in water and base or normal organic solutions.
 
Chitosan Description:
 
Chitosan is a linear polysaccharide composed of randomly distributed β-(1-4)-linked D-glucosamine (deacetylated unit) and N-acetyl-D-glucosamine (acetylated unit). It is made by treating shrimp and other crustacean shells with the alkali sodium hydroxide.
 
Chitosan has a number of commercial and possible biomedical uses. It can be used in agriculture as a seed treatment and biopesticide, helping plants to fight off fungal infections. In winemaking it can be used as a fining agent, also helping to prevent spoilage. In industry, it can be used in a self-healing polyurethane paint coating. In medicine, it may be useful in bandages to reduce bleeding and as an antibacterial agent; it can also be used to help deliver drugs through the skin.
 
More controversially, chitosan has been asserted to have use in limiting fat absorption, which would make it useful for dieting, but there is evidence against this.
 
Other uses of chitosan that have been researched include use as a soluble dietary fiber.
 
Chitosan is extracted from chitin, insoluble in water but soluble in dilute acid and absorbed by human body. As the firdt derivate, it's chemical constitution is macromolecule alkalescent polysaccharide polymer with cation. It has peculiar physical, chemical properties and bioactive function.
 
Chitosan is listed as follows:
A. High Density Chitosan
B. High Viscosity Chitosan
C. Industrial Grade Chitosan
D. Food Grade Chitosan
E. Medical Grade Chitosan
F. Low Molecular Weight Chitosan
G. Aroxymethyl Chitosan
H. Chitosan Oligosaccharide
 
Chitosan Applications:
 
1)Food Field:
Used as food additives, thickeners, preservatives fruits and vegetables, fruit juice clarifying agent, forming agent, adsorbent, and health food.
2)Medicine, health care products field:
As the chitosan non-toxic,has anti-bacterial, anti-inflammatory, hemostatic, and immune function, can be used as artificial skin, self-absorption of surgical sutures, medical dressing Branch, bone, tissue engineering scaffolds, enhance liver function, improve digestive function, blood fat, lowering blood sugar, inhibiting tumor metastasis, and adsorption and complexation of heavy metals and can be excreted, and so on, was vigorously applied to health food and drug additives.
3)Environmental protection field:
Chitosan and its derivatives is a good flocculant for wastewater treatment and metal recovery from metal-containing waste water; in textile field: as a mordant, health care fabric, sizing agents, printing and dyeing
4).Agricultural field:
As growth promoters, bio-pesticides, feed additives, seeds, etc.
5)Field of tobacco
Tobacco sheet used as adhesives, low-tar filter and so on.
 
Chitosan is refined from deacetylation of chitin which is extracted from deep-sea Alaska crab cods. As the only basic polysaccharide among natural polysaccharides, this product has many physical and chemical characteristics and physiological activities. Precisely, this product can control cholesterol, inhibit bacterial activity, prevent and control high blood pressure, absorb and excrete heavy metals, maintain humidity and strengthen immunity. In food industry, this product can be used as antibacterial agent, fruit and vegetable preservative and antioxidant. There are many special functional groups in molecular chain, so the chitosan can be manufactured into many products according to different reactions on functional groups, such as acylation, sulfation and oxidation, grafting and crosslinking, hydroxyethylation and hydroxymethylation. These products can be used in many fields, including medicine, food, chemical, cosmetic, water treatment, metal extraction and recovery, biochemical and biomedical engineering. There are many types of chitosan, including GS-chitosan oligosaccharide, high density type, special molecular weight type, medical/food / industrial grade type, water soluble type and specialized type.
Chitosan can inhibit growth and reproduction of fungi, bacteria, and virus. When this product is used as coating preservation, it can inhibit respiratory metabolism and water loss of fruits and vegetables, thus slowing their aging process of organization and structure and effectively extending their postharvest life. This product can also be used as antioxidant. In heating process, free iron ions are released from meat hemoglobin and they form chelates with chitosan, thus their catalytic activity is inhibited.
 
Chitosan Usage:
 
Agricultural and horticultural use
The agricultural and horticultural uses for chitosan, primarily for plant defense and yield increase, are based on how this glucosamine polymer influences the biochemistry and molecular biology of the plant cell. The cellular targets are the plasma membrane and nuclear chromatin. Subsequent changes occur in cell membranes, chromatin, DNA, calcium, MAP Kinase, oxidative burst, reactive oxygen species, callose pathogenesis-related (PR) genes and phytoalexins.
 
Natural biocontrol and elicitor
In agriculture, chitosan is used primarily as a natural seed treatment and plant growth enhancer, and as an ecologically friendly biopesticide substance that boosts the innate ability of plants to defend themselves against fungal infections. The natural biocontrol active ingredients, chitin/chitosan, are found in the shells of crustaceans, such as lobsters, crabs, and shrimp, and many other organisms, including insects and fungi. It is one of the most abundant biodegradable materials in the world.
 

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Protein phosphatase 1 regulatory subunit 3B (172-180) LAB GRADE 97%

Creative peptides is specialized in the process development and the manufacturing of bioactive peptides. We offer custom peptide synthesis, process development, GMP manufacturing as well as catalog products. We supply Protein phosphatase 1 regulatory subunit 3B (172-180).http://www.creative-peptides.com/product/protein-phosphatase-regulatory-subunit-3b-item-ta-229-15739.html

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Safety Pure Amino Acid 3,5-Diiodo-L-Thyronine T2 Powder 1041-01-6

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Safety Pure Amino Acid 3,5-Diiodo-L-Thyronine T2 Powder 1041-01-6
 
3,5-Diiodo-L-Thyronine Basic Information:
 
Product Name: 3,5-Diiodo-L-Thyronine
Synonyms: T2;Diiodothyronine;3,5-Diiodo-L-Thyronine;3,5-Diiodothyronine;
CAS: 1041-01-6
MF: C15H13I2NO4
MW: 525.08
EINECS: 213-867-7
Melting point: 255-260°C (dec.)
Storage temp.: 2-8°C
Chemical Properties: Off-White Solid
Product Categories: Medicine intermediate;Amino Acids 13C, 2H, 15N;Amino Acids & Derivatives;Intermediates;Labeling and Diagnostics Reagents
Usage: Of interest for the early detection and treatment of congenital or drug-induced hypothyroidism.
 

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