Pharmaceutical raw materials used in synthesizing new medications

chemical-categories

White Crystalline Powder Treat Breast Cancer Trilostane 13647-35-3

Welcome to inquiry!

Email: tony@kafenbio.com

WhatsApp: +8618002259573

Skype: tony_14616

www.pharmhormone.com

 
White Crystalline Powder Treat Breast Cancer Trilostane 13647-35-3
 
Trilostane Basic Info.
 
Product Name: Trilostane
Synonym: Trilostane;Vetoryl;Modrenal
CAS: 13647-35-3
Molecular Formula: C20H27NO3
Molecular Weight: 329.43
Einecs No.: 237-133-0
Assay: 99%
Melting point: 264 °C
Storage temp.: -20°C Freezer
Storage: Shading, confined preservation
Grade: Pharmaceutical Grade
Appearance: White crystalline powder
Product Categories: Intermediates & Fine Chemicals;Pharmaceuticals;Steroids;Inhibitor;FULVICIN.
Usage: 
(1)Trilostane can inhibit cortical hormone in the process of synthesis of 3 beta dehydrogenase, make the cortisol, aldosterone synthesis decreased;
(2)Clinically used in the treatment of Cushing syndrome (hypercortisolism) and primary aldosteronism. 
(3)Trilostane also had significantly effect to decreased serum testosterone level.
 
Trilostane Description:
 
Trilostane is used in the treatment of Cushing's syndrome. It is normally used in short-term treatment until permanent therapy is possible. Trilostane blocks an enzyme involved in the production of several steroids including cortisol. Inhibiting this enzyme inhibits the production of cortisol. In Cushing's syndrome, the adrenal gland overproduces steroids. Although steroids are important for various functions of the body, too much can cause problems. Trilostane reduces the amount of steroids produced by the adrenal gland.
Trilostane produces suppression of the adrenal cortex by inhibiting enzymatic conversion of steroids by 3-beta-hydroxysteroid dehydrogenase/delta 5,4 ketosteroid isomerase, thus blocking synthesis of adrenal steroids.
 
Side effect:Symptoms of overdose include darkening of skin, drowsiness or tiredness, loss of appetite, mental depression, skin rash, and/or vomiting.
 
Trilostane Application:
 
Trilostane can suppress cortical hormone synthesis process of 3 beta dehydrogenase, make cortisol, aldosterone synthesis reduce, clinical used in the treatment of Cushing syndrome(cortisol increase disease) and primary aldosteronism,the effect is not good than testosterone metyrapone. This product has significantly reduced blood testosterone level role, may relevant to its inhibit synthetic.
 

Properties Suppliers
White Ghrp-2 Human Growth Hormone For Bodybuilding 158861-67-7

Welcome to inquiry!

Email: tony@kafenbio.com

WhatsApp: +8618002259573

Skype: tony_14616

www.pharmhormone.com

 
White Ghrp-2 Human Growth Hormone For Bodybuilding 158861-67-7
 
GHRP 2 Basic Info.:
 
Product name: GHRP-2 (GHRP-2 Acetate )
Synonym: Pralmorelin; GHRP2; D-Alanyl-3-(2-naphthalenyl)-D-alanyl-L-alanyl-L-tryptophyl-D-phenylalanyl-L-lysinamide; GHRP 2; 
CAS: 158861-67-7
MF: C45H55N9O6
MW: 817.9749
Purity: 98%
Appearance: White powder
Density: 1.27g/cm3
Boiling point: 1265.3°C at 760 mmHg
Flashing point: 719°C
Function: To stimulate GH secretion, appetite, and to gain weight
 
GHRP 2 Description:
 
GHRP-2 is a synthetic agonist of ghrelin, the newly-discovered gut peptide which binds to the GH secretagogue receptor. Ghrelin has two major effects, stimulating both GH secretion and appetite/meal initiation. GHRP-2 has been extensively studied for its utility as a GHS. Since the test subjects body will end up producing more GH this way, fat will be reduced while lean muscle mass is increased. Along with this, IGF-1 levels will increase, as well, along with the different hypothalamus functions.
 
GHRP 2 Application:
 
GHRP-2 basically acts exactly like ghrelin. It can induce food consumption just like ghrelin and stimulate GH secretion, too. When infused, GHRP-2 makes the GH levels in the body increase a lot and it can induce cell cAMP secretion the way that GRF tends to, as well.
GHRP-2 as a Growth Hormone Secretagogue
 
GHRP-2 has been studied extensively for its utility as a growth hormone secretagogue (GHS). Scientists have discovered that the Growth Hormone Releasing Peptide-2 increases the natural production of growth hormone (GH). In the early 90’s, one of the most famous studies was performed and later published in 1997 in the Journal of Endocrinology and Metabolism. This study further exemplifies the theory that growth hormone releasing peptides (including Ipamorelin and GHRP-6) could help hormone deficient adults and children. Ever since these major scientific studies, GHRP-2 has been widely produced. With other scientific labs confirming the results from their studies, GHRP-2 can in fact work for those who lack the ability to make adequate human growth.
 

Properties Suppliers
White Powder Male Sex Enhancement Yohimbine HCL For Sex Protein Supplements 65-19-0

Welcome to inquiry!

Email: tony@kafenbio.com

WhatsApp: +8618002259573

Skype: tony_14616

www.pharmhormone.com

 
White Powder Male Sex Enhancement Yohimbine HCL For Sex Protein Supplements 65-19-0
 
Yohimbine HCL Basic Info:
 
Product Name: Yohimbine Hydrochloride
Other name: Corynine; Aphrodine
Synonyms: Corynine Hydrochloride;Aphrodine Hydrochloride;Aphrosol Hydrochloride;Yohimbe HCL;Yohimbine HCL;Yohimbine Hydrochloride
CAS: 65-19-0
MF: C21H27ClN2O3
MW: 390.9
EINECS: 200-600-4
Purity: 99%
Melting point: 288-290 °C (dec.)(lit.)
alpha: 99 º (c=1%, H2O, dry subst)
refractive index: 103 ° (C=1, H2O)
storage temp.: Refrigerator
solubility: H2O: 10 mg/mL
Chemical Properties: white to slightly yellow powder
Usage: 
(1)Indole alkaloid with α2-adrenergic blocking activity. Mydriatic. Used in the treatment of neurological disorders.
(2)alpha adrenergic blocker, mydriatic, antidepressant
(3)vasodilator, neuromodulator
(4)a2-adrenergic antagonist, used for erectile dysfunction
(5)Erectile dysfunction & Mydriatic agent
Product Categories: Alkaloids;Biochemistry;Indole Alkaloids;Natural Plant Extract;Adrenoceptor;Adrenoceptors;Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;API;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;ADENYL;Inhibitors.
 
Yohimbine HCL Description:
 
Yohimbine has been shown in human studies to be effective in the treatment of male impotence. Yohimbine has been shown to be effective in the treatment of orgasmic dysfunction in men. Yohimbine has also been used to treat hypoactive sexual desire disorder (reduced libido) in women. Increase muscular tension or urinary function no damage sex; Accelerate human body energy metabolism, increase energy supply.
 
Yohimbine has been used to facilitate recall of traumatic memories in the treatment of post traumatic stress disorder (PTSD). Use of yohimbine outside therapeutic settings may not be appropriate for persons suffering from PTSD. In pharmacology, yohimbine is used as a probe for α 2-adrenoceptor. In veterinary medicine, yohimbine is used to reverse anesthesia from the drug xylazine in small and large animals.
 
Yohimbine HCL Application:
 
Yohimbine readily penetrates the and produces a complex pattern of responses in lower doses than those required to produce peripheral alpha-adrenergic blockade. These include, anti-diuresis, a general picture of central excitation including elevation of blood pressure and heart rate, increased motor activity, nervousness, irritability and tremor. Sweating, nausea and vomiting are common after parenteral administration of the drug. Also, dizziness, headache skin flushing reported when used orally.
 
Generally, this drug is not proposed for use in females and certainly must not be used during pregnancy. Neither is this drug proposed for use in pediatric, geriatric or cardio-renal patients with gastric or duodenal ulcer history. Nor should it be used in conjunction with mood- modifying drugs such as antidepressants, or in psychiatric patients in general.
 
Renal diseases and patient's sensitive to the drug. In view of the limited and inadequate information at hand, no precise tabulation can be offered of additional contraindications. It is important that your doctor check your progress at regular visits to make sure that this medicine is working properly. Use yohimbine exactly as directed by your doctor. Do not use more of it and do not use it more often than ordered. If too much is used, the risk of side effects such as fast heartbeat and high blood pressure is increased.
 

Properties Suppliers
Wilms tumor protein (235-243) LAB GRADE 97%

Creative peptides is specialized in the process development and the manufacturing of bioactive peptides. We offer custom peptide synthesis, process development, GMP manufacturing as well as catalog products. We supply Wilms tumor protein (235-243).http://www.creative-peptides.com/product/wilms-tumor-protein-item-ta-415-29283.html

Properties Suppliers
Wilms tumor protein (317-327) LAB GRADE 97%

Creative peptides is specialized in the process development and the manufacturing of bioactive peptides. We offer custom peptide synthesis, process development, GMP manufacturing as well as catalog products. We supply Wilms tumor protein (317-327).http://www.creative-peptides.com/product/wilms-tumor-protein-item-ta-414-29282.html

Properties Suppliers
Wilms tumor protein (332-347) LAB GRADE 97%

Creative peptides is specialized in the process development and the manufacturing of bioactive peptides. We offer custom peptide synthesis, process development, GMP manufacturing as well as catalog products. We supply Wilms tumor protein (332-347).http://www.creative-peptides.com/product/wilms-tumor-protein-item-ta-417-29285.html

Properties Suppliers
Wilms tumor protein (337-347) LAB GRADE 97%

Creative peptides is specialized in the process development and the manufacturing of bioactive peptides. We offer custom peptide synthesis, process development, GMP manufacturing as well as catalog products. We supply Wilms tumor protein (337-347).http://www.creative-peptides.com/product/wilms-tumor-protein-item-ta-416-29284.html

Properties Suppliers
Wiskott-Aldrich syndrome protein (262-281) LAB GRADE 97%

Creative peptides is specialized in the process development and the manufacturing of bioactive peptides. We offer custom peptide synthesis, process development, GMP manufacturing as well as catalog products. We supply Wiskott-Aldrich syndrome protein (262-281).http://www.creative-peptides.com/product/wiskott-aldrich-syndrome-protein-item-ta-158-10127.html

Properties Suppliers
Women Prohormones Steroids Progestone Progesterone Hormon Altrenogest 850-52-2

Welcome to inquiry!

Email: tony@kafenbio.com

WhatsApp: +8618002259573

Skype: tony_14616

www.pharmhormone.com

 
Women Prohormones Steroids Progestone Progesterone Hormon Altrenogest 850-52-2 
 
Altrenogest Basic Info.
 
Product Name: Altrenogest 
CAS No.: 850-52-2  
Formula: C21H26O2  
Molecular Weight: 310.47  
EINECS: 212-703-1  
Density: 1.15 g/cm3  
Boiling Point: 495.6 °C at 760 mmHg  
Flash Point: 210.1 °C    
Storage: store in cool, dry, ventilated place.
PackAge: Foil Bag or According to Your Requirements.
 
Altrenogest Application:
 
Altrenogest is indicated (labeled) to suppress estrus in mares to allow a more predictable occurrence of estrus following withdrawal of the drug. It is used clinically to assist mares to establish normal cycles during the transitional period from anestrus to the normal breeding season often in conjunction with an artificial photoperiod. It is more effective in assisting in pregnancy attainment later in the transition period. One group of authors (Squires et al. 1983) suggest selecting mares with considerable follicular activity (mares with one or more follicles 20 mm or greater in size) for treatment during the transitional phase. Mares that have been in estrus for 10 days or more and have active ovaries are also considered to be excellent candidates for progestin treatment.
 
Altrenogest is effective in normally cycling mares for minimizing the necessity for estrus detection, for the synchronization of estrus and permitting scheduled breeding. Estrus will ensue 2-5 days after treatment is completed and most mares ovulate between 8-15 days after withdrawal. Altrenogest is also effective in suppressing estrus expression in show mares or mares to be raced. Although the drug is labeled as contraindicated during pregnancy, it has been demonstrated to maintain pregnancy in oophorectomized mares and may be of benefit in mares who abort due to sub-therapeutic progestin levels.
 
Altrenogest Adverse Effects/Warnings:
 
Adverse effects of altrenogest appear to be minimal when used at labeled dosages. One study (Shideler et al. 1983) found negligible changes in hematologic and most "standard" laboratory tests after administering altrenogest to 4 groups of horses (3 dosages, 1 control) over 86 days. Occasionally, slight changes in Ca++, K+, alkaline phosphatase and AST were noted in the treatment group, but values were only slightly elevated and only noted sporadically. No pattern or definite changes could be attributed to altrenogest. No outward adverse effects were noted in the treatment group during the trial.
 
The following people should not handle the product:
1).Women who are or suspect that they are pregnant
2).Anyone with thrombophlebitis or thromboembolic disorders or with a history of these events
3).Anyone having cerebrovascular or coronary artery disease
4).Women with known or suspected carcinoma of the breast
5).People with known or suspected estrogen-dependent neoplasia
6).Women with undiagnosed vaginal bleeding
7).People with benign or malignant tumor which developed during the use of oral contraceptives or other estrogen containing products.
 

Properties Suppliers
X antigen family member 1 (17-32) LAB GRADE 97%

Creative peptides is specialized in the process development and the manufacturing of bioactive peptides. We offer custom peptide synthesis, process development, GMP manufacturing as well as catalog products. We supply X antigen family member 1 (17-32).http://www.creative-peptides.com/product/x-antigen-family-member-item-ta-534-31335.html

Properties Suppliers