Pharmaceutical raw materials used in synthesizing new medications

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ADP-ribosylation factor GTPase-activating protein 3 (152-160) LAB GRADE 97%

Creative peptides is specialized in the process development and the manufacturing of bioactive peptides. We offer custom peptide synthesis, process development, GMP manufacturing as well as catalog products. We supply ADP-ribosylation factor GTPase-activating protein 3 (152-160).http://www.creative-peptides.com/product/adp-ribosylation-factor-gtpase-activating-protein-item-ta-052-1753.html

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Antibiotics Alkaloid Pharmaceutical Raw Materials Chloramphenicol 56-75-7

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Antibiotics Alkaloid Pharmaceutical Raw Materials Chloramphenicol 56-75-7
 
Chloramphenicol Basic Info.:
 
Product Name: Chloramphenicol / Chlornitromycin
Alias: 99.5%
CAS: 56-75-7
Einecs: 200-287-4
Molecular formula: C11H12Cl2N2O5
Molecular weight: 323.13
Package: 25kg/ drum or as required
Usage: can be used as pharmaceutical material
Storage: Shading, confined preservation
Appearance: white crystal powder.
Usage: Genus of broad-spectrum antibacterial antibiotics,it is the treatment of typhoid, paratyphoid medicine, one of the effective drug for the treatment of anaerobic infections, secondly for the treatment of various susceptible disease caused by microbial infections .
 
Product Introduction of Chloramphenicol:
 
Chloramphenicol is on the World Health Organization's List of Essential Medicines, a list of the most important medications needed in a basic health system. Although unpublished, recent research suggests chloramphenicol could also be applied to frogs to prevent their widespread destruction from fungal infections. It has recently been discovered to be a life-saving cure for chytridiomycosis in amphibians.
 
The most serious adverse effect associated with chloramphenicol treatment is bone marrow toxicity, which may occur in two distinct forms: bone marrow suppression, which is a direct toxic effect of the drug and is usually reversible, and aplastic anemia, which is idiosyncratic (rare, unpredictable, and unrelated to dose) and generally fatal.
 
Chloramphenicol Effect:
 
Because of its excellent blood-brain barrier penetration (far superior to any of the cephalosporins), chloramphenicol remains the first-choice treatment for staphylococcal brain abscesses. It is also useful in the treatment of brain abscesses due to mixed organisms or when the causative organism is not known.
 
Use of intravenous chloramphenicol has also been associated with gray baby syndrome, a phenomenon resulting from newborn infants' inability to metabolize chloramphenicol in the body. Other less serious reactions include fever, rashes, headache, and confusion. Prescription use is usually associated with monitoring of a patient's complete blood count. The drug should be discontinued upon appearance of reticulocytopenia, leukopenia, thrombocytopenia, anemia, or any other abnormal blood study findings attributable to chloramphenicol.
 

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Antifungal Pharmaceutical Raw Materials Ketoconazole / Nizoral 65277-42-1

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Antifungal Pharmaceutical Raw Materials Ketoconazole / Nizoral 65277-42-1
 
Ketoconazole Basic Info.:
 
Product Name: Ketoconazole
Synonyms: Ketoconazole; Nizoral
CAS: 65277-42-1
EINECS: 265-667-4  
MF: C26H28Cl2N4O4 
MW: 531.43 
Assay: 99.5%
Standard: USP34
Package: 25 kilogram/cardboard drum
Appearance: White Powder 
Usage: Inhibits cytochrome P-450 dependent steps in the biosynthesis of steroid hormones in vivo. Antimetastatic and antineoplastic. 
 
Ketoconazole Introduction:
 
Ketoconazole is an antifungal medication that fights infections caused by fungus.
Ketoconazole is not for use in treated fungal infections of the fingernails or toenails. This medicine is also not for use in treating prostate cancer or Cushing syndrome.
 
This medicine should be used only when you cannot use other antifungal medications. Ketoconazole can cause serious harm to your liver that may result in liver transplant or cause death.
Ketoconazole may also be used for purposes not listed in this medication guide.
 
Ketoconazole Employ:
 
This medicine should be used only when you cannot use other antifungal medications. Ketoconazole can cause serious harm to your liver that may result in liver transplant or cause death.
 

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Beauty Cosmetic Peptide Snap-8 Acetyl Glutamyl Heptapeptide-3 868844-74-0

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Beauty Cosmetic Peptide Snap-8 Acetyl Glutamyl Heptapeptide-3 868844-74-0
 
Snap-8 Basic Info.:
 
Product Name: Snap-8 (Acetyl Glutamyl Heptapeptide-3)
Synonyms: SNAP-8;Acetyl GlutaMyl Heptapeptide-3;Acetyl GlutaMyl Octapeptide-3;Acetyl Octapeptide-3;Acetyl Octapetpide-3;Acetyl Octapeptide-8.
CAS: 868844-74-0
MF: C41H70N16O16S
MW: 1075.16
Product Categories: Cosmetics beauty peptide
Density: 1.56
Usage: anti-wrikle
 
SNAP-8 Application:
 
The synthesis of SNAP-8 involves a final freeze-drying step. Freeze-dried products are commonly obtained as a polymorphous crystalline powder, which means that locally some aggregates and differences in crystal size may appear. This polymorphism is not associated to chemical differences and extensive work performed by the analytical department has ensured the homogeneity of the product. SNAP-8 is presented either as SNAP-8 Powder, an octapeptide in powder form which can be easily dissolved in water, or as SNAP-8 Solution, an aqueous solution containing 0.5 g/L of the powder version. It can be incorporated at the final stage of the manufacturing product, provided the temperature is below 40 degrees Celsius. Taking into consideration the concentration of peptide in SNAP-8 Solution, it is recommended that 3 to 10% of the solution is present in the final formulation in order to obtain significant anti-wrinkle activity.
 
SNAP-8 is a mimic of the N-terminal end of SNAP-25 which competes with SNAP-25 for a position in the SNARE complex, thereby modulating its formation. If the SNARE complex is slightly destabilized, the vesicle can not release neurotransmitters efficiently and therefore muscle contraction is attenuated, preventing the formation of lines and wrinkles
 
The Benefits of SNAP-8:
 
- Reduces the depth of wrinkles on the face caused by the contraction of muscles of facial expression, especially in the forehead and around the eyes.
- A safer, cheaper, and milder alternative to Botulinum Toxin, topically targeting the same wrinkle-formation mechanism in a very different way.
- Has been incorporated in cosmetic formulations such as emulsions, gels, sera, etc., where removal of the deep lines or wrinkles in the forehead or around the eyes area is desired.
 
SNAP-8 Solution:
 
INCI name: Water, Acetyl Glutamyl Heptapeptide-1 
Appearance: Transparent solution
Contents: 0.05 % SNAP-8 Powder 
Preservative: 0.3 % Phenonip
 
SNAP-8 Storage And Shelf Life:
 
SNAP-8 Powder and SNAP-8 Solution must be kept in a cool, dark and clean place to ensure a shelf life of at least twelve months. For long term storage it is recommended to store both forms at 4 ºC which extends shelf life to at least eighteen months. In rare cases, refrigerated storage of SNAP-8 Solution can cause precipitation of the preservative. This does not affect the integrity of the product.
 

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H/ACA ribonucleoprotein complex subunit 2 isoform a (144-153) LAB GRADE 97%

Creative peptides is specialized in the process development and the manufacturing of bioactive peptides. We offer custom peptide synthesis, process development, GMP manufacturing as well as catalog products. We supply H/ACA ribonucleoprotein complex subunit 2 isoform a (144-153).http://www.creative-peptides.com/product/h-aca-ribonucleoprotein-complex-subunit-isoform-a-item-ta-120-5662.html

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High Purity Estrogen Raw Female Steroid Powders Ethynyl Estradiol 57-63-6

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High Purity Estrogen Raw Female Steroid Powders Ethynyl Estradiol 57-63-6
 
Ethynyl Estradiol Basic Info.:
 
Ethynyl estradiol Basic information
Product Name: Ethynyl estradiol
CAS: 57-63-6
MF: C20H24O2
MW: 296.4
EINECS: 200-342-2
Chemical Properties: Off-White to Light-Yellow Crystalline Powder
Usage: A metabolite of 17A-Ethynylestradiol
Usage: A synthetic steroid with high oral estrogenic potency
Usage estrogen, plus progestogen as oral contraceptive
Standard: USP28
 
Ethynyl Estradiol Description:
 
Ethinylestradiol is a man-made form of the naturally occurring female hormone called oestrogen.
It is prescribed to treat period (menstrual) problems, and also to help ease menopausal symptoms. It is usually prescribed alongside another female hormone called a progestogen.
 
Ethinyl estradiol also sometimes written as ethinylestradiol, ethynyl estradiol, or ethinyl? Stradiol, is a derivative of 17β -estradiol (E2), the major endogenous estrogen in humans. EE is an orally bioactive estrogen used in many formulations of combined oral contraceptive pills. It is one of the most commonly used medications for this purpose.
 
Estinyl was a preparation of EE alone that was used for the management of menopausal symptoms and female hypogonadism.
EE is released into the environment as a xenoestrogen from the urine and feces of people who take it as a medication.
 
Ethynyl Estradiol Application:
 
When estrogen is prescribed for a woman with a uterus, progestin should also be initiated to reduce the risk of endometrial cancer. A woman without a uterus does not need progestin. Use of estrogen, alone or in combination with a progestin, should be with the lowest effective dose and for the shortest duration consistent with treatment goals and risks for the individual woman. Patients should be reevaluated periodically as clinically appropriate (e.g., 3-month to 6-month intervals) to determine if treatment is still necessary. For women who have a uterus, adequate diagnostic measures, such as endometrial sampling, when indicated, should be undertaken to rule out malignancy in cases of undiagnosed persistent or recurring abnormal vaginal bleeding.
Short-term cyclic use for treatment of moderate to severe vasomotor symptoms, vulval and vaginal atrophy associated with the menopause, the lowest dose and regimen that will control symptoms should be chosen and medication should be discontinued as promptly as possible.
Attempts to discontinue or taper medication should be made at 3- to 6-month intervals. The usual dosage range is 1 to 5 mg injected every 3 to 4 weeks.
For treatment of female hypoestrogenism due to hypogonadism 1.5 to 2 mg injected at monthly intervals.
 

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Melanoma antigen preferentially expressed in tumors (100-108) LAB GRADE 97%

Creative peptides is specialized in the process development and the manufacturing of bioactive peptides. We offer custom peptide synthesis, process development, GMP manufacturing as well as catalog products. We supply Melanoma antigen preferentially expressed in tumors (100-108).http://www.creative-peptides.com/product/melanoma-antigen-preferentially-expressed-in-tumors-item-ta-386-29119.html

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Melanoma antigen preferentially expressed in tumors (142-151) LAB GRADE 97%

Creative peptides is specialized in the process development and the manufacturing of bioactive peptides. We offer custom peptide synthesis, process development, GMP manufacturing as well as catalog products. We supply Melanoma antigen preferentially expressed in tumors (142-151).http://www.creative-peptides.com/product/melanoma-antigen-preferentially-expressed-in-tumors-item-ta-387-29124.html

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Melanoma antigen preferentially expressed in tumors (300-309) LAB GRADE 97%

Creative peptides is specialized in the process development and the manufacturing of bioactive peptides. We offer custom peptide synthesis, process development, GMP manufacturing as well as catalog products. We supply Melanoma antigen preferentially expressed in tumors (300-309).http://www.creative-peptides.com/product/melanoma-antigen-preferentially-expressed-in-tumors-item-ta-388-29197.html

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Melanoma antigen preferentially expressed in tumors (301-309) LAB GRADE 97%

Creative peptides is specialized in the process development and the manufacturing of bioactive peptides. We offer custom peptide synthesis, process development, GMP manufacturing as well as catalog products. We supply Melanoma antigen preferentially expressed in tumors (301-309).http://www.creative-peptides.com/product/melanoma-antigen-preferentially-expressed-in-tumors-item-ta-390-29204.html

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