Pharmaceutical raw materials used in synthesizing new medications

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99% Male Enhancement Drug Raw Material Powder Tadalafil Cialis 171596-29-5

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99% Male Enhancement Drug Raw Material Powder Tadalafil Cialis 171596-29-5
 
Tadalafil Basic Info:
 
Product Name: Tadalafil
Synonyms: Tadalafil;Cialis;IC 351;Cialis IC35
CAS: 171596-29-5
MF: C22H19N3O4
MW: 389.4
EINECS: 200-835-2
Assay: 99.5%min
Appearance: off-white crystalline
Product Categories: Active Pharmaceutical Ingredients;Cnbio;Erectile Dysfunction;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;API's;Steroid and Hormone;Inhibitor;API;Tadalafil;NUCYNTA;Pyridines ,Halogenated Heterocycles 
Usage: an oral drug that is used for treating impotence (the inability to attain or maintain a penile erection) and benign prostatic hyperplasia (BPH)
 
Tadalafil Description:
 
Cialis (Tadalifil), a phosphodiesterase type 5 inhibitor, is used to treat erectile dysfunction (ED) and decreased libido in males. Cialis works by aiding relaxation of blood vessels and increasing blood flow in the penis during sexual arousal, resulting in improved erectile function.
Tadalafil is used for Erectile dysfunction and pulmonary hypertension, the rapid absorption after oral administration, 2 hours to reach maximum observed plasma concentrations of average time after administration of (Cmax). Influence of absorption rate and degree is not affected by food tadalafil, so it can be with or without with clothes and food.
 
Tadalafil is an oral drug for the treatment of ED, used in the treatment of erectile dysfunction and premature ejaculation, erectile function impairment and premature ejaculation has very significant improvements. There are over 1500 documents to prove the caused by different causes impotence premature ejaculation, knew the success rate is above 80%, and show its reliable curative effect, through the use of more than 20 million people worldwide, proved its long-term stability, the safety of 25 to 60 minutes of work function to coincide with a time needed for foreplay, knew the time adjustment in the highest drug concentration time, help both husband and wife a satisfactory sex life.
 
Tadalafil Application:
 
Since people who have taken tadalafil within the past 48 hours cannot take organic nitrates to relieve angina (such as glyceryl trinitrate spray), these patients should seek immediate medical attention if they experience anginal chest pain.In the event of a medical emergency, paramedics and medical personnel should be notified of any recent doses of tadalafil.
 
Tadalafil is metabolized predominantly by the hepatic CYP3A4 enzyme system. The presence of other drugs which induce this system can shorten tadalafil half-life and reduce serum levels, and hence efficacy, of the drug.
 
Tadalafil has been used in approximately 15,000 men participating in clinical trials, and over eight million men worldwide (primarily in the post-approval/post-marketing setting). The most common side effects when using tadalafil are headache, stomach discomfort or pain, indigestion, burping, acid reflux, back pain, muscle aches, flushing, and stuffy or runny nose. These side effects reflect the ability of PDE5 inhibition to cause vasodilation (cause blood vessels to widen), and usually go away after a few hours. Back pain and muscle aches can occur 12 to 24 hours after taking the drug, and the symptom usually disappears after 48 hours.
 

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99.9% Pramoxine Hydrochloride Anesthetic Anodye CAS 637-58-1 Pramoxine HCl

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99.9% Pramoxine Hydrochloride Anesthetic Anodye CAS 637-58-1 Pramoxine HCl
 
Pramoxine HCL Basic Info.:
 
Product Name: Pramoxine Hydrochloride
CAS: 637-58-1
EINECS number: 211-293-1
Molecular formula: C17H28ClNO3
Molecular Weight: 329.8621
Boiling point: 427 °C at 760 mmHg
Flash Point: 123.5 °C
Vapor Pressure: 1.7E-07mmHg at 25 °C
Appearance: White or almost white crystalline powder
 
Pramoxine HCL Description:
 
Pharmacologic study revealed it to be potent and of low acute and subacute toxicity, well tolerated by most mucous membranes and of a low sensitizing index in man. Like other local anesthetics, paramoxine decreases the permeability of neuronal membranes to sodium ions, blocking both initiation and conduction of nerve impulses. Depolarization and repolarization of excitable neural membranes is thus inhibited, leading to numbness.
 
Pramoxine HCL Applications:
 
Topical anesthetics are used to relieve pain and itching caused by conditions such as sunburn or other minor burns, insect bites or stings, poison ivy, poison oak, poison sumac, and minor cuts and scratches. Pramocaine and dibucaine are also common ingredients in over the counter hemorrhoid preparations.
 

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Anabolic Raw Steroid Powder Trenbolone Base For Muscle Building 10161-33-8

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Anabolic Raw Steroid Powder Trenbolone Base For Muscle Building 10161-33-8
 
Trenbolone Base Basic Info.
 
Product name: Trenbolone
Alias: Trenbolone;RU2341;Trienbolone;b-Trenbolone;
CAS: 10161-33-8
MF: C18H22O2
MW: 270.37
Assay: 99%
Melting point: 170°C
Storage temp.: 2-8°C
Appearance: Light yellow crystal powder
Product Categories: Steroids;Intermediates & Fine Chemicals;Pharmaceuticals;Steroid and Hormone;Finished Steroid and Hormone;trenbolone series
Usage: It can be used for muscle building. Trenbolone is literally the most powerful anabolic steroid conventionally and commercially available. Trenbolone is an extremely powerful, impressive, and versatile anabolic steroid that tends to suffer from a heavy shroud of rumor, misunderstanding, and mysticism.
 
Trenbolone Base Description:
 
Trenbolone is essentially a derivative of Nandrolone with some very significant differences in its chemical properties and strength. Trenbolone and its parent hormone Nandrolone both belong to a class/category of anabolic steroids known as 19-nor compounds, or 19-nors (short for 19-nortestosterone). 19-nor anabolic steroids are labeled as such because they lack the 19th carbon on their structure - this carbon exists on Testosterone and all other anabolic steroids with the exception of 19-nor compounds, such as Nandrolone and Trenbolone.
 
Trenbolone is also much more potent than testosterone at suppressing endogenous androgen production. This makes clear the fact that estrogen is not the only culprit with negative feedback inhibition, as here there is no buildup of this hormone to report here. There is however some activity as a progestin inherent in this compound, as trenbolone is a 19-nortestosterone (nandrolone) derivative (a trait characteristic of these compounds).
 

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Cartilage intermediate layer protein 1 preproprotein (779-787) LAB GRADE 97%

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Dapoxetine Hydrochloride Sex Enhancement Powder Dapoxetine HCl 129938-20-1

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Dapoxetine Hydrochloride Sex Enhancement Powder Dapoxetine HCl 129938-20-1
 
Dapoxetine HCL Basic Info:
 
Product Name: Dapoxetine HCL
Synonyms: Dapoxetine HCL; Dapoxetine Hydrochloride; Rimonabant 75000; LY-21044
Alias: Priligy; Dapoxetine Hydrochloride
CAS No: 129938-20-1
MF: C9H7ClN2O5
MW: 258.62
Purity: 99%
Melting point: 175-179°C
Storage temp.: -20°C Freezer
Appearance: Off-white Cryst, odorless, slightly sweet, soluble in water and alcohol.
Usage:
(1)Dapoxetine hydrochloride is a short-acting novel selective serotonin reuptake inhibitor marketed for the treatment of premature ejaculation in men. Premature ejaculation (PE) is the most common male sexual disorder, estimated to affect up to 30% of men. D
(2)Selective serotonin reuptake inhibitor (SSRI)
Product Categories: Intermediates & Fine Chemicals;Pharmaceuticals;Amines;Aromatics;Inhibitors;Dapoxetine Hydrochloride
 
Dapoxetine HCL Description:
 
Premature ejaculation (PE) is the most common male sexual dysfunction. Dapoxetine hydrochloride, belonging to a class of drugs known as selective serotonin reuptake inhibitors or, was the first drug originally approved for the on-demand treatment of men with PE. We aimed to compare the intravaginal ejaculatory latency time (IELT), patient-reported global impression of change (PGIC), and adverse effect (AE) incidence associated with the use of dapoxetine (30 mg and 60 mg) versus placebo, and evaluate the differences in administering 60 mg versus 30 mg as on-demand medical oral therapy for the treatment of PE via a literature review and meta-analysis. Relevant randomized controlled trials (RCTs) were identified from PubMed, EMBASE, and Cochrane Central Register of Controlled Trials (Cochrane Library) databases. Ultimately, a total of seven RCTs with 8039 patients were included. Our meta-analysis demonstrated that dapoxetine (in the 30 mg and 60 mg subgroup) resulted in significantly higher IELT, PGIC, and AE incidence relative to the placebo, with higher proportions observed for 60 mg versus 30 mg of dapoxetine administration. The most common AEs were mild and tolerable. We conclude that dapoxetine (particularly the 60 mg dosage) may be considered a safe and effective drug for patients with PE.
 
Dapoxetine HCL Application:
 
Dapoxetine hydrochloride is a drug that is used to treat premature ejaculation in men. It is available by prescription and is taken orally, prior to sexual intercourse. The drug belongs to the class called serotonin reuptake inhibitors (SSRIs), which have mainly been used to treat depression.
 
Sexual dysfunction, including premature ejaculation, is an extremely common condition worldwide. The cause of premature ejaculation has not been fully elucidated, but may include both psychological and physiological factors. Premature ejaculation refers to a short ejaculation time, which can affect the satisfaction of both partners during sexual intercourse.
 

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Eukaryotic translation initiation factor 4 gamma 1 (1248-1256) LAB GRADE 97%

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GDNF family receptor alpha-1 isoform b preproprotein (117-130) LAB GRADE 97%

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Human type 3 inositol 1,4,5-trisphosphate receptor (2354-2362) LAB GRADE 97%

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Insulin-like growth factor-II mRNA binding protein 3 (199-207) LAB GRADE 97%

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Insulin-like growth factor-II mRNA binding protein 3 (515-523) LAB GRADE 97%

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