Pharmaceutical raw materials used in synthesizing new medications

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Cartilage intermediate layer protein 1 preproprotein (779-787) LAB GRADE 97%

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Dapoxetine Hydrochloride Sex Enhancement Powder Dapoxetine HCl 129938-20-1

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Dapoxetine Hydrochloride Sex Enhancement Powder Dapoxetine HCl 129938-20-1
 
Dapoxetine HCL Basic Info:
 
Product Name: Dapoxetine HCL
Synonyms: Dapoxetine HCL; Dapoxetine Hydrochloride; Rimonabant 75000; LY-21044
Alias: Priligy; Dapoxetine Hydrochloride
CAS No: 129938-20-1
MF: C9H7ClN2O5
MW: 258.62
Purity: 99%
Melting point: 175-179°C
Storage temp.: -20°C Freezer
Appearance: Off-white Cryst, odorless, slightly sweet, soluble in water and alcohol.
Usage:
(1)Dapoxetine hydrochloride is a short-acting novel selective serotonin reuptake inhibitor marketed for the treatment of premature ejaculation in men. Premature ejaculation (PE) is the most common male sexual disorder, estimated to affect up to 30% of men. D
(2)Selective serotonin reuptake inhibitor (SSRI)
Product Categories: Intermediates & Fine Chemicals;Pharmaceuticals;Amines;Aromatics;Inhibitors;Dapoxetine Hydrochloride
 
Dapoxetine HCL Description:
 
Premature ejaculation (PE) is the most common male sexual dysfunction. Dapoxetine hydrochloride, belonging to a class of drugs known as selective serotonin reuptake inhibitors or, was the first drug originally approved for the on-demand treatment of men with PE. We aimed to compare the intravaginal ejaculatory latency time (IELT), patient-reported global impression of change (PGIC), and adverse effect (AE) incidence associated with the use of dapoxetine (30 mg and 60 mg) versus placebo, and evaluate the differences in administering 60 mg versus 30 mg as on-demand medical oral therapy for the treatment of PE via a literature review and meta-analysis. Relevant randomized controlled trials (RCTs) were identified from PubMed, EMBASE, and Cochrane Central Register of Controlled Trials (Cochrane Library) databases. Ultimately, a total of seven RCTs with 8039 patients were included. Our meta-analysis demonstrated that dapoxetine (in the 30 mg and 60 mg subgroup) resulted in significantly higher IELT, PGIC, and AE incidence relative to the placebo, with higher proportions observed for 60 mg versus 30 mg of dapoxetine administration. The most common AEs were mild and tolerable. We conclude that dapoxetine (particularly the 60 mg dosage) may be considered a safe and effective drug for patients with PE.
 
Dapoxetine HCL Application:
 
Dapoxetine hydrochloride is a drug that is used to treat premature ejaculation in men. It is available by prescription and is taken orally, prior to sexual intercourse. The drug belongs to the class called serotonin reuptake inhibitors (SSRIs), which have mainly been used to treat depression.
 
Sexual dysfunction, including premature ejaculation, is an extremely common condition worldwide. The cause of premature ejaculation has not been fully elucidated, but may include both psychological and physiological factors. Premature ejaculation refers to a short ejaculation time, which can affect the satisfaction of both partners during sexual intercourse.
 

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Eukaryotic translation initiation factor 4 gamma 1 (1248-1256) LAB GRADE 97%

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GDNF family receptor alpha-1 isoform b preproprotein (117-130) LAB GRADE 97%

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Human type 3 inositol 1,4,5-trisphosphate receptor (2354-2362) LAB GRADE 97%

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Insulin-like growth factor-II mRNA binding protein 3 (199-207) LAB GRADE 97%

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Insulin-like growth factor-II mRNA binding protein 3 (515-523) LAB GRADE 97%

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Peptides Carbetocin Acetate Contracting Uterus Control Bleeding 37025-55-1

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Peptides Carbetocin Acetate Contracting Uterus Control Bleeding 37025-55-1
 
Carbetocin Acetate Basic Info.:
 
Product Name: Carbetocin Acetate
Synonyms: (Butyryl1,Tyr(Me)2)-1-Carbaoxytocin Trifluoroacetate Salt;Carbetocin;Carbetocin Trifluoroacetate Salt;
CAS: 37025-55-1
MF: C45H69N11O12S
MW: 988.17
EINECS: 253-312-6
Storage temp.: -15°C
Product Categories: Peptide;Vasopressin and Oxytocin receptor;Intermediates & Fine Chemicals;Pharmaceuticals;Other APIs
Usage: An obstetric drug used to control postpartum hemorrhaging.
 
Carbetocin Acetate it is used to control bleeding after giving birth. Like oxytocin, it causes contraction of the uterus.
 

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Pharmaceutical Chemicals Isotretinoin Accutane For AcneTreatment 4759-48-2

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Pharmaceutical Chemicals Isotretinoin Accutane For AcneTreatment 4759-48-2

Isotretinoin Basic Info.:

Product Name: Isotretinoin

Synonyms: 13-ra;Accutane;Isoretinoin;Isotrex;Neovitaminaacid;Ro-4-3780

CAS: 4759-48-2

MF: C20H28O2

MW: 300.44

Assay: 99%

EINECS: 225-296-0

Product Categories: Antibiotics;Organic acids;APIs;Intermediates & Fine Chemicals;Pharmaceuticals;Retinoids

Air & Water Reactions: Insoluble in water.

Packing:100g/foil bag

Chemical Property: The melting point of 174~175 Centigrade.

UV maximum absorption: 354nm ( 39800).

Usage: Used as a treatment for severe acne. Presently being studied in conjuction with the treatment of photoaged skin.

Isotretinoin Usage:

As the retinoid, there are strong and fast proliferation inhibition and differentiation of skin gland cell function, effective on severe nodular cystic acne. The gastrointestinal absorption is better, while the local medication invalid. Other drugs used to treat invalid serious acne, cystic acne, acne conglobata, rosacea, ichthyosis, keratosis follicularis and pityriasis rubra pilaris and other skin diseases also have a certain effect. For severe acne. Anti skin dyskeratosis medicine. For the treatment of severe acne and other disorders. Belong to whitening prohormones, can made INTO injections! Works very well in whitening!

Application Of Isotretinoin:

1. Medical applications: the lack of nutrition of the elderly, thin, for severe burns and had the operation people.

2. Sports purpose: promote muscle growth, increased training and endurance training load, it has never been proved.

3. Adaption: Trauma, chronic infection, malnutrition and wasting disease and All kinds of refractory anemia.

 

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Polysorbate 80 Safe Organic Solvents for Used in food Emulsifier 9005-70-3

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Polysorbate 80 Safe Organic Solvents for Used in food Emulsifier 9005-70-3
 
Polysorbate 80 Basic Info.:
 
Product Name: Polysorbate 80
Synonyms: Tween 85
CAS: 9005-70-3
MF: C24H44O6
MW: 428.600006103516
EINECS: 500-019-9
Form: viscous liquid
EPA Substance Registry System: Sorbitan, 
Product Categories: Ester Ether Type (Surfactants);Functional Materials;Nonionic Surfactants;Surfactants;Biochemistry;
Nonionic Surfactants (for Biochemistry);Surfactants (for Biochemistry)
 
Polysorbate 80 Employ:
 
Polysorbate 80 is often used in food and other products as an emulsifier.Polysorbate 80 is used as an emulsifier in the manufacture of medications for parenteral administration, most notably in the popular anti-arrhythmic amiodarone. It is also part of the adjuvant used in some European and Canadian influenza vaccines.
 
Polysorbate 80 Introduction:
 
Polysorbate 80 (commercially also known as Tween 80, a registered trademark of ICI Americas, Inc.) is a nonionic surfactant and emulsifier derived from polyethoxylated sorbitan and oleic acid, and is often used in foods. Polysorbate 80 is a viscous, water soluble yellow liquid. The hydrophilic groups in this compound are polyethers also known as polyoxyethylene groups which are polymers of ethylene oxide. In the nomenclature of polysorbates, the numeric designation following polysorbate refers to the lipophilic group, in this case the oleic acid (see polysorbate for more detail). 
 
Polysorbate 80 is used as an emulsifier in foods, particularly in ice cream. Here, polysorbate is added to up to 0.5% (v/v) concentration and makes the ice cream smoother and easier to handle, as well as increasing its resistance to melting. Adding this substance prevents milk proteins from completely coating the fat droplets. This allows them to join together in chains and nets, which hold air in the mixture, and provide a firmer texture that holds its shape as the ice cream melts.
 

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