Pharmaceutical raw materials used in synthesizing new medications

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Zinc finger MYND domain-containing protein 15 isoform 1 (138-147) LAB GRADE 97%

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99% Benzocaine Hydrochloride Local Anesthetic Agents Benzocaine HCL 23239-88-5

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99% Benzocaine Hydrochloride Local Anesthetic Agents Benzocaine HCL 23239-88-5
 
Benzocaine HCL Basic Info.:
 
Product Name: Benzocaine HCL
Synonyms: Ethyl 4-Aminobenzoate Hydrochloride;Benzocaine Hcl;Benzocaine Hydrochloride;Benzocaine Hydrochl;
CAS: 23239-88-5
MF: C9H11NO2.ClH
MW: 201.65
Assays: 99%
Melting point: 92°C
Boiling point: 310°C, 183-184°C (1.87×103Pa)
Density: 1.17
Stability: Stable. Combustible.
Chemical Properties: White odourless crystals.
Uses: 
(1)The goods are used to relieve pain for the local anesthetic, wounds, ulcers and hemorrhoids facial, also are cough suppressants retreat intermediates.
(2)Used in cosmetic ultraviolet absorption, local anesthetics and used to relieve pain in the wound, ulcer surface and Hemorrhoids.
 
Benzocaine HCL Description:
 
Benzocaine is also called amino ethyl benzoate, a colorless or white orthorhombic needle-like crystals or crystalline powder. Benzocaine hydrochloride salt is the hydrochloride salt form of the local anesthetic benzocaine, with the same pharmacological effects of benzocaine and weaker effect of anesthesia than procaine. Local absorption is slow with lasting effect. It cannot be used for anesthesia as a result of not being dissolved in water. It can be used for pain relief and anti-itch. Benzocaine hydrochloride is usually made into powder or oil paste and used to heal wounds, ulcers, burns, skin abrasions and hemorrhoids.
 
Benzocaine is commonly found, particularly in Britain, as an impurity in street cocaine. Whilst giving a numbing effect similar to cocaine on users' gums it does not actually produce the effects of cocaine. But in terms of an orally based saliva drug test benzocaine can and has been mistaken for a false positive for cocaine.
 
Benzocaine HCL Applications:
 
Benzocaine HCL works by creating a chemical barrier that halts the build-up of sodium, which accumulates as the nerve endings are stimulated by pain. When sodium builds up, electrical signals also build in the nerve endings. These are eventually transmitted to the brain, which interprets the signals as pain.
 
Benzocaine is a local anesthetic commonly used as a topical pain reliever or in cough drops. It is the active ingredient in many over-the-counter anesthetic ointments such as products for oral ulcers. It is also combined with antipyrine to form A/B otic drops to relieve ear pain and remove earwax
 
Benzocaine is used as a key ingredient in numerous pharmaceuticals:
Over the counter throat lozenges such as Cepacol.
Some glycerol-based ear medications for use in removing excess wax as well as relieving ear conditions such as otitis media and swimmers ear.
Some previous diet products such as Ayds.
Some condoms designed to prevent premature ejaculation. Benzocaine largely inhibits sensitivity on the penis, and can allow for an erection to be maintained longer (in a continuous act) by delaying ejaculation. Conversely, an erection will also fade faster if stimulus is interrupted.
Benzocaine mucoadhesive patches have been used in reducing orthodontic pain.
In Poland it is included, together with menthol and zinc oxide, in the liquid powder (not to be confused with the liquid face powder) used mainly after mosquito stings. Today's ready made Pudroderm was once used there as pharmaceutical compound.
 

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Anabolic Steroid Hormones Drostanolone Enanthate For Cutting Cycles 472-61-145

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Anabolic Testosterone Steroid Hormone Raw Powder Nandrolone Decanoate 360-70-3

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Anabolic Testosterone Steroid Hormone Raw Powder Nandrolone Decanoate 360-70-3
 
Nandrolone Decanoate Basic Info.:
 
Product Name: Nandrolone Decanoate
Alias: Deca-Durabolin; 19-Nortestoterone Decanoate
CAS No: 360-70-3
MF: C28H44O3
MW: 428.65
Einecs No: 206-639-3
Purity: 99%
MOQ(minimum order quantity: 10gram
Standard: Enterprise Standard
Appearance: Light white powder, odourless. Refrigeration preservation.
Refrigeration save: Room temperature more than 20 Celsius degree to agglomerate, or so 30 Celsius degree into a liquid.
Usage: Can be used as pharmaceutical material, used to treat anemia associated with chronic (long-term) kidney failure. 
 
Nandrolone Decanoate Description: 
 
The decanoate ester supplies a slow release of nandrolone from the site of injection, continuation for up to 3 weeks.
Suchlike , nandrolone displays relatively powerful anabolic attributes. however, its tissue-building action is attended by weak androgenic facilities.
 
The modest attributes of nandrolone decanoate have made it among the most pop injectable steroids in global, highly preferred by athletes for its power to promote important strength and lean muscle mass increases without strong androgenic or estrogenic side effects.
 
Nandrolone Decanoate Applications: 
 
In earlier years, the only pharmaceutical injectables that were both widely available to bodybuilders and economical. Estrogen control did not then exist. For this reason, Deca's low aromatizing properties were then quite useful. Deca therefore won wide popularity.
Steroids Hormone Nandrolone Decanoate/Deca-Durabolin/19-Nortestoterone decanoate/DECA powders/CAS No: 360-70-3 Use after surgery for chronic wasting disease, serious illness, and weak thin, infirm, osteoporosis, infantile dysplasia, aplastic anemia, etc.
 
Deca Durabolin is that this compound is relatively mild in terms of adverse side effects on the scalp and skin. This is because the 5-alpha reductase enzyme acts to reduce the potency of nandrolone, while in contrast many other anabolic steroids are unaffected by this enzyme,potency is actually increased by it.
 

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Breast Cancer Treatment Female Sex Hormone Steroid Powder Progesterone 57-83-0

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Breast Cancer Treatment Female Sex Hormone Steroid Powder Progesterone 57-83-0
 
Progesterone Basic Info.:
 
Product Name: Progesterone 
Synonyms: Progestin;PRIMOLUT
CAS: 57-83-0 
MF: C21H30O2 
MW: 314.46 
EINECS: 200-350-6 
mp:  128-132°C(lit.)
alpha:  186°(c=1, ethanol) 
refractive index:  182 ° (C=2, Dioxane) 
storage temp:  Store at RT 
solubility  H2O:  25 mg/mL, may be clear to slightly hazy
Appearance:  white powder
Water Solubility:  <0.1 g/100 mL at 19°C  
Stability:  Stable. Incompatible with strong oxidizing agents. 
 
Progesterone Description:
 
Progesterone is a female Progesterone Hormones important for the regulation of ovulation and menstruation. 
 
Women take progesterone by mouth for inducing menstrual periods who have not yet reached menopause but are not having periods due to a lack of progesterone in the body; And treating abnormal uterine bleeding associated with hormonal imbalance, and severe symptoms of premenstrual syndrome (PMS). Progesterone is also used to prevent overgrowth in the lining of the uterus in postmenopausal women who are receiving estrogen hormone replacement therapy. Progesterone is also used in combination with the hormone estrogen to "oppose estrogen" as part of hormone replacement therapy. If estrogen is given without progesterone, estrogen increases the risk of uterine cancer.
 
One of progesterone's most important functions is to cause the endometrium to secrete special proteins during the second half of the menstrual cycle, preparing it to receive and nourish an implanted fertilized egg. If implantation does not occur, estrogen and progesterone levels drop, the endometrium breaks down and menstruation occurs.
 
If a pregnancy occurs, progesterone is produced in the placenta, and levels remain elevated throughout the pregnancy. The combination of high estrogen and progesterone levels suppress further ovulation during pregnancy. Progesterone also encourages the growth of milk-producing glands in the breast during pregnancy.
 
High progesterone levels are believed to be partly responsible for symptoms of premenstrual syndrome (PMS), such as breast tenderness, feeling bloated and mood swings. When you skip a period, it could be because of failure to ovulate and subsequent low progesterone levels.  
 
Progesterone Applications:
 
Progesterone is a female Progesterone Hormones important for the regulation of ovulation and menstruation. 
Women take progesterone by mouth for inducing menstrual periods who have not yet reached menopause but are not having periods due to a lack of progesterone in the body; And treating abnormal uterine bleeding associated with hormonal imbalance, and severe symptoms of premenstrual syndrome (PMS). Progesterone is also used to prevent overgrowth in the lining of the uterus in postmenopausal women who are receiving estrogen hormone replacement therapy. Progesterone is also used in combination with the hormone estrogen to "oppose estrogen" as part of hormone replacement therapy. If estrogen is given without progesterone, estrogen increases the risk of uterine cancer.
 

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Factory Direct Supplying Anabolic Steroids Hormone Powder 7-Keto DHEA 566-19-8

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Factory Direct Supplying Anabolic Steroids Hormone Powder 7-Keto DHEA 566-19-8
 
7-Keto-DHEA Basic Info.:
 
Product name: 7-keto DHEA
Synonym: 7-KETO; 5-androstene-3b-ol-7, 17-dione; 5-ANDROSTEN-3-BETA-OL-7, 17-DIONE; 7-KETO-DEHYDROEPIANDROSTERONE; 7-KETO DHEA; 7-hydroxydehydroepiandrosterone; 7-Oxo-dehydroepiandrosterone; Androst-5-ene-7, 17-dione, 3beta-hydroxy
CAS Number: 566-19-8
Assay: 98.5%min
Molecular Formula: C19H26O3
Molecular Weight: 302.41
Appearance: White crystalline powder
 
7-Keto-DHEA Description:
 
7-keto-DHEA is a by-product of dehydroepiandrosterone (DHEA), a chemical that is formed in the body. DHEA is a "parent hormone" produced by glands near the kidneys. But unlike DHEA, 7-keto-DHEA is not converted to steroid hormones such as androgen and estrogen. Taking 7-keto-DHEA by mouth or applying it to the skin does not increase the level of steroid hormones in the blood.People take 7-keto-DHEA to speed up the metabolism and heat production to promote weight loss. 7-keto-DHEA is also used to improve lean body mass and build muscle, increase the activity of the thyroid gland, boost the immune system, enhance memory, and slow aging.
 
7-Keto-DHEA Applications:
 
7-oxodehydroepiandrosterone (7-oxo DHEA and more commonly known as the brand name 7-keto) is one of three oxygenated metabolites of Dehydroepiandrosterone, and these three oxygenated metabolites interconvert with one another but do not convert back into parent DHEA; 7-keto supplementation is a way to get these three oxygenated metabolites without using DHEA supplementation, and DHEA may form androgenic and estrogenic hormones via an alternate metabolic pathway (which 7-keto does not participate in).
 
7-keto supplementation is mostly known to not be hormonal; it can interact with steroid metabolism but the exact manner in which it does it not fully elucidated. It does appear to have anti-cortisol mechanisms as the enzymes that activate cortisol (from the relatively inactive precursors of cortisone and corticosterone) are the same that interconvert these oxygenated metabolites. Although it appears to be anti-cortisol by its mechanisms, there is insufficient evidence to support these mechanisms in the body following oral supplementation.
 
Studies using 7-keto supplementation tend to note an increased metabolic rate later on during a caloric restriction period (which is secondary to reducing the rate of metabolic rate decline associated with dieting, and becoming a relative increase) although the quantity of data on this is pretty minimal if we exclude studies with possible conflicts of interest or those that use 7-keto alongside a multitude of supplements.7-keto appears to be a somewhat promising non-hormonal fat burning agent but requires more evidence on both of those claim.
 

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GMP Pharmaceuticals Standard 1,5-Dimethyl-Hexylamin As Antitubercular 543-82-8

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GMP Pharmaceuticals Standard 1,5-Dimethyl-Hexylamin As Antitubercular 543-82-8
 
1,5-Dimethyl-Hexylamin Basic Info.:
 
Product Name: 1,5-Dimethyl-Hexylamin (2-Amino-6-Methylheptane )
Synonyms: 1,5-Dimethyl-Hexylamin;6-Methyl-2-Heptanamin
CAS: 543-82-8
MF: C8H19N
MW: 129.24
EINECS: 208-851-1
Boiling point: 154-156 °C(lit.)
Density: 0.767 g/mL at 25 °C(lit.)
Refractive index: n20/D 1.422(lit.)
Fp: 120 °F
Storage temp.: Flammables area
Chemical Properties: Clear colorless to light yellow liquid.
Product Categories: Amines;Building Blocks;C8;Chemical Synthesis;Nitrogen Compounds;Organic Building Blocks;Aliphatics;Inhibitors;Intermediates;Fine chemicals.
Usage: 1,5-Dimethylhexylamine is an aliphatic secondary amine which shows leucine aminotransferase inhibition. 1,5-Dimethylhexylamine is used in the preparation of glycosyl β-amino acids with antitubercular activity.
 

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High Purity Male Hormone Raw Anabolic Trenbolone Steroids Mibolerone 3704-09-4

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High Purity Male Hormone Raw Anabolic Trenbolone Steroids Mibolerone 3704-09-4
 
Mibolerone Basic Info.:
 
Product Name: Mibolerone
CAS: 3704-09-4
MF: C20H30O2
MW: 302.45
EINECS: 223-046-5
Chemical Properties: White Crystalline Solid
Usage: Synthetic anabolic steroid related to testosterone. Controlled substance (anabolic steroid)
 
Mibolerone Description:
 
Mibolerone was initially as a veterinary product used to keep female dogs under control while they are in heat by shutting down the cycling of their ovaries. With proper timing, breeders are able to regulate the heat cycles of their bitches. Eventually, athletes began to utilize the product in order to boost aggression before events. It was even rumored that Mike Tyson was on Cheque Drops during the infamous ear biting incident during his bout with Holyfield. 
 
However, the late great guru Dan Duchaine discovered the application of Cheque Drops in modern bodybuilding far before that. The drops went in and out of production several times, before making a recent insurgence due to the piqued interest in the product thanks to the growing popularity of ultimate fighting circles.
 
Mibolerone Applications:
 
It is most commonly used by athletes about 30-40 minutes before their sporting event. Cheque drops are placed under the athletes tongue, and effects including aggression, strength and adrenaline rush are felt rapidly.  The drug leaves the body with in approximately four hours.
 
As well as being one of the most androgenic compounds, mibolerone is also one of the most toxic.   The most common side effect is progesterone related gynecomastia because it is a 19 nor-androgen.  
 

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Pharmaceutical Raw Materials Desonide Used To Treat Atopic Dermatitis 638-94-8

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Pharmaceutical Raw Materials Desonide Used To Treat Atopic Dermatitis 638-94-8
 
Desonide Basic info:
 
Product Name: Desonide
Synonyms: Prednacinolone;Desonide;D-2083;Steroderm
CAS NO.: 638-94-8
Molecular Formula: C24H32O6
Molecular Weight: 416.51
EINECS: 211-351-6
Assay: 99.5%
Melting point: 272-274°C
Storage temp.: Refrigerator
Appearance: White powder
Product Categories: Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals;Steroids;SPORANOX;Hormone Drugs.
Usage: 
(1)With acetal-based adrenal cortex hormones;
(2)Antifungal;
(3)Anti-inflammatory. Desonide has also been found as an impurity in budesonide (B689490).
How to use desonide topical: Use this medication only on the skin.
 
Desonide Description:
 
Desonide Ointment, 0.05% contains Desonide (Pregna - 1,4 - diene - 3,20 - dione,11,21 - dihydroxy - 16,17 - [(1 - methylethylidene)bis(oxy)] - ,(11β,16α)) a synthetic corticosteroid for topical dermatologic use. The corticosteroids constitute a class of primary synthetic steroids used topically as anti-inflammatory and antipruritic agents.
 
Chemically, Desonide, the active ingredient in Desonide Ointment, 0.05% is C24H32O6. It has the following structural formula:
 
The molecular weight of Desonide is 416.51. It is a white to off-white powder. The solubility of Desonide in distilled water saturated with ether is 184 mg/L.
Each gram of Desonide Ointment, 0.05% contains 0.5 milligram of Desonide microdispersed in a base of white petrolatum.
 
Desonide Application:
 
Desonide belongs to the group of medications known as topical corticosteroids. It is used to Treat various skin conditions, including rashes. It works by reducing inflammation and itching.
 
Endogenous eczema clinical cure rate, the overall curative effect is distinct, and the low Incidence of adverse reactions, is a safe and effective external cortex hormone.
 
Wash your hands. Before applying the medication, clean and dry the affected area. Apply a thin film of the medication to the affected area and gently rub in, usually 2-3 times daily, or as directed by your doctor. If using the gel, apply the gel usually only 2 times daily. Do not bandage, wrap, or cover the area unless you are instructed to do so by your doctor. If used in the diaper area on an infant, do not use tight-fitting diapers or plastic pants.
 
After applying the medication, wash and dry your hands, unless you are using this medication to treat the hands. When applying this medication near the eyes, avoid getting it in the eyes because this may worsen or cause glaucoma, or cause irritation. Also, avoid getting this medication in the nose or mouth. If you get this medication in your eyes, nose, or mouth, rinse immediately with plenty of water.
 

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Pharmaceutical Raw Materials Elubiol Dichlorophenylimidazoldioxolan 67914-69-6

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Pharmaceutical Raw Materials Elubiol Dichlorophenylimidazoldioxolan 67914-69-6
 
Elubiol Basic Info.:
 
Product Name: Elubiol (Dichlorophenylimidazoldioxolan)
Synonyms: Elubiol; Dichlorophenylimidazoldioxolan
CAS: 67914-69-6
Molecular formula: C27H30Cl2N4O5
Molecular weight: 561.46
Quantity: 500Kgs stock inventory. 10 tons per month
Appearance white to off white crystalline powder
Identification of HPLC
Loss on drying 0.50%max
The heavy metal 20ppmmax
The purity of (HPLC) 99.00%min
Content (titrimetric) 99.0%-101.0%
Package: 25kg paperboard barrel
 
Elubiol Description:
 
New posaconazole is a novel imidazole fungicides could inhibit the fungal sterol biosynthesis, wheat, and other components of the changes of cell membrane lipid compounds. Killing of Candida albicans, Histoplasma, Blastomyces dermatitidis and Coccidioides immitis, to dandruff, sterilization and regulate the skin grease in the washing products.
 
The main structure and the new azole ketoconazole are exactly the same, only at the end of keto ester instead of ketoconazole in. The Pityrosporum ovale of dandruff, two is the most potent inhibitor. The new azole included in the INCI directory, list the EU cosmetics ingredients and the Ministry of "health standard Chinese names of raw materials of Cosmetics International Directory", can be legally used in cosmetics.
 

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