Pharmaceutical raw materials used in synthesizing new medications

chemical-categories

Anabolic Testosterone Steroid Hormone Raw Powder Nandrolone Decanoate 360-70-3

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Anabolic Testosterone Steroid Hormone Raw Powder Nandrolone Decanoate 360-70-3
 
Nandrolone Decanoate Basic Info.:
 
Product Name: Nandrolone Decanoate
Alias: Deca-Durabolin; 19-Nortestoterone Decanoate
CAS No: 360-70-3
MF: C28H44O3
MW: 428.65
Einecs No: 206-639-3
Purity: 99%
MOQ(minimum order quantity: 10gram
Standard: Enterprise Standard
Appearance: Light white powder, odourless. Refrigeration preservation.
Refrigeration save: Room temperature more than 20 Celsius degree to agglomerate, or so 30 Celsius degree into a liquid.
Usage: Can be used as pharmaceutical material, used to treat anemia associated with chronic (long-term) kidney failure. 
 
Nandrolone Decanoate Description: 
 
The decanoate ester supplies a slow release of nandrolone from the site of injection, continuation for up to 3 weeks.
Suchlike , nandrolone displays relatively powerful anabolic attributes. however, its tissue-building action is attended by weak androgenic facilities.
 
The modest attributes of nandrolone decanoate have made it among the most pop injectable steroids in global, highly preferred by athletes for its power to promote important strength and lean muscle mass increases without strong androgenic or estrogenic side effects.
 
Nandrolone Decanoate Applications: 
 
In earlier years, the only pharmaceutical injectables that were both widely available to bodybuilders and economical. Estrogen control did not then exist. For this reason, Deca's low aromatizing properties were then quite useful. Deca therefore won wide popularity.
Steroids Hormone Nandrolone Decanoate/Deca-Durabolin/19-Nortestoterone decanoate/DECA powders/CAS No: 360-70-3 Use after surgery for chronic wasting disease, serious illness, and weak thin, infirm, osteoporosis, infantile dysplasia, aplastic anemia, etc.
 
Deca Durabolin is that this compound is relatively mild in terms of adverse side effects on the scalp and skin. This is because the 5-alpha reductase enzyme acts to reduce the potency of nandrolone, while in contrast many other anabolic steroids are unaffected by this enzyme,potency is actually increased by it.
 

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Breast Cancer Treatment Female Sex Hormone Steroid Powder Progesterone 57-83-0

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Breast Cancer Treatment Female Sex Hormone Steroid Powder Progesterone 57-83-0
 
Progesterone Basic Info.:
 
Product Name: Progesterone 
Synonyms: Progestin;PRIMOLUT
CAS: 57-83-0 
MF: C21H30O2 
MW: 314.46 
EINECS: 200-350-6 
mp:  128-132°C(lit.)
alpha:  186°(c=1, ethanol) 
refractive index:  182 ° (C=2, Dioxane) 
storage temp:  Store at RT 
solubility  H2O:  25 mg/mL, may be clear to slightly hazy
Appearance:  white powder
Water Solubility:  <0.1 g/100 mL at 19°C  
Stability:  Stable. Incompatible with strong oxidizing agents. 
 
Progesterone Description:
 
Progesterone is a female Progesterone Hormones important for the regulation of ovulation and menstruation. 
 
Women take progesterone by mouth for inducing menstrual periods who have not yet reached menopause but are not having periods due to a lack of progesterone in the body; And treating abnormal uterine bleeding associated with hormonal imbalance, and severe symptoms of premenstrual syndrome (PMS). Progesterone is also used to prevent overgrowth in the lining of the uterus in postmenopausal women who are receiving estrogen hormone replacement therapy. Progesterone is also used in combination with the hormone estrogen to "oppose estrogen" as part of hormone replacement therapy. If estrogen is given without progesterone, estrogen increases the risk of uterine cancer.
 
One of progesterone's most important functions is to cause the endometrium to secrete special proteins during the second half of the menstrual cycle, preparing it to receive and nourish an implanted fertilized egg. If implantation does not occur, estrogen and progesterone levels drop, the endometrium breaks down and menstruation occurs.
 
If a pregnancy occurs, progesterone is produced in the placenta, and levels remain elevated throughout the pregnancy. The combination of high estrogen and progesterone levels suppress further ovulation during pregnancy. Progesterone also encourages the growth of milk-producing glands in the breast during pregnancy.
 
High progesterone levels are believed to be partly responsible for symptoms of premenstrual syndrome (PMS), such as breast tenderness, feeling bloated and mood swings. When you skip a period, it could be because of failure to ovulate and subsequent low progesterone levels.  
 
Progesterone Applications:
 
Progesterone is a female Progesterone Hormones important for the regulation of ovulation and menstruation. 
Women take progesterone by mouth for inducing menstrual periods who have not yet reached menopause but are not having periods due to a lack of progesterone in the body; And treating abnormal uterine bleeding associated with hormonal imbalance, and severe symptoms of premenstrual syndrome (PMS). Progesterone is also used to prevent overgrowth in the lining of the uterus in postmenopausal women who are receiving estrogen hormone replacement therapy. Progesterone is also used in combination with the hormone estrogen to "oppose estrogen" as part of hormone replacement therapy. If estrogen is given without progesterone, estrogen increases the risk of uterine cancer.
 

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Factory Direct Supplying Anabolic Steroids Hormone Powder 7-Keto DHEA 566-19-8

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Factory Direct Supplying Anabolic Steroids Hormone Powder 7-Keto DHEA 566-19-8
 
7-Keto-DHEA Basic Info.:
 
Product name: 7-keto DHEA
Synonym: 7-KETO; 5-androstene-3b-ol-7, 17-dione; 5-ANDROSTEN-3-BETA-OL-7, 17-DIONE; 7-KETO-DEHYDROEPIANDROSTERONE; 7-KETO DHEA; 7-hydroxydehydroepiandrosterone; 7-Oxo-dehydroepiandrosterone; Androst-5-ene-7, 17-dione, 3beta-hydroxy
CAS Number: 566-19-8
Assay: 98.5%min
Molecular Formula: C19H26O3
Molecular Weight: 302.41
Appearance: White crystalline powder
 
7-Keto-DHEA Description:
 
7-keto-DHEA is a by-product of dehydroepiandrosterone (DHEA), a chemical that is formed in the body. DHEA is a "parent hormone" produced by glands near the kidneys. But unlike DHEA, 7-keto-DHEA is not converted to steroid hormones such as androgen and estrogen. Taking 7-keto-DHEA by mouth or applying it to the skin does not increase the level of steroid hormones in the blood.People take 7-keto-DHEA to speed up the metabolism and heat production to promote weight loss. 7-keto-DHEA is also used to improve lean body mass and build muscle, increase the activity of the thyroid gland, boost the immune system, enhance memory, and slow aging.
 
7-Keto-DHEA Applications:
 
7-oxodehydroepiandrosterone (7-oxo DHEA and more commonly known as the brand name 7-keto) is one of three oxygenated metabolites of Dehydroepiandrosterone, and these three oxygenated metabolites interconvert with one another but do not convert back into parent DHEA; 7-keto supplementation is a way to get these three oxygenated metabolites without using DHEA supplementation, and DHEA may form androgenic and estrogenic hormones via an alternate metabolic pathway (which 7-keto does not participate in).
 
7-keto supplementation is mostly known to not be hormonal; it can interact with steroid metabolism but the exact manner in which it does it not fully elucidated. It does appear to have anti-cortisol mechanisms as the enzymes that activate cortisol (from the relatively inactive precursors of cortisone and corticosterone) are the same that interconvert these oxygenated metabolites. Although it appears to be anti-cortisol by its mechanisms, there is insufficient evidence to support these mechanisms in the body following oral supplementation.
 
Studies using 7-keto supplementation tend to note an increased metabolic rate later on during a caloric restriction period (which is secondary to reducing the rate of metabolic rate decline associated with dieting, and becoming a relative increase) although the quantity of data on this is pretty minimal if we exclude studies with possible conflicts of interest or those that use 7-keto alongside a multitude of supplements.7-keto appears to be a somewhat promising non-hormonal fat burning agent but requires more evidence on both of those claim.
 

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GMP Pharmaceuticals Standard 1,5-Dimethyl-Hexylamin As Antitubercular 543-82-8

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GMP Pharmaceuticals Standard 1,5-Dimethyl-Hexylamin As Antitubercular 543-82-8
 
1,5-Dimethyl-Hexylamin Basic Info.:
 
Product Name: 1,5-Dimethyl-Hexylamin (2-Amino-6-Methylheptane )
Synonyms: 1,5-Dimethyl-Hexylamin;6-Methyl-2-Heptanamin
CAS: 543-82-8
MF: C8H19N
MW: 129.24
EINECS: 208-851-1
Boiling point: 154-156 °C(lit.)
Density: 0.767 g/mL at 25 °C(lit.)
Refractive index: n20/D 1.422(lit.)
Fp: 120 °F
Storage temp.: Flammables area
Chemical Properties: Clear colorless to light yellow liquid.
Product Categories: Amines;Building Blocks;C8;Chemical Synthesis;Nitrogen Compounds;Organic Building Blocks;Aliphatics;Inhibitors;Intermediates;Fine chemicals.
Usage: 1,5-Dimethylhexylamine is an aliphatic secondary amine which shows leucine aminotransferase inhibition. 1,5-Dimethylhexylamine is used in the preparation of glycosyl β-amino acids with antitubercular activity.
 

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High Purity Male Hormone Raw Anabolic Trenbolone Steroids Mibolerone 3704-09-4

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High Purity Male Hormone Raw Anabolic Trenbolone Steroids Mibolerone 3704-09-4
 
Mibolerone Basic Info.:
 
Product Name: Mibolerone
CAS: 3704-09-4
MF: C20H30O2
MW: 302.45
EINECS: 223-046-5
Chemical Properties: White Crystalline Solid
Usage: Synthetic anabolic steroid related to testosterone. Controlled substance (anabolic steroid)
 
Mibolerone Description:
 
Mibolerone was initially as a veterinary product used to keep female dogs under control while they are in heat by shutting down the cycling of their ovaries. With proper timing, breeders are able to regulate the heat cycles of their bitches. Eventually, athletes began to utilize the product in order to boost aggression before events. It was even rumored that Mike Tyson was on Cheque Drops during the infamous ear biting incident during his bout with Holyfield. 
 
However, the late great guru Dan Duchaine discovered the application of Cheque Drops in modern bodybuilding far before that. The drops went in and out of production several times, before making a recent insurgence due to the piqued interest in the product thanks to the growing popularity of ultimate fighting circles.
 
Mibolerone Applications:
 
It is most commonly used by athletes about 30-40 minutes before their sporting event. Cheque drops are placed under the athletes tongue, and effects including aggression, strength and adrenaline rush are felt rapidly.  The drug leaves the body with in approximately four hours.
 
As well as being one of the most androgenic compounds, mibolerone is also one of the most toxic.   The most common side effect is progesterone related gynecomastia because it is a 19 nor-androgen.  
 

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Pharmaceutical Raw Materials Desonide Used To Treat Atopic Dermatitis 638-94-8

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Pharmaceutical Raw Materials Desonide Used To Treat Atopic Dermatitis 638-94-8
 
Desonide Basic info:
 
Product Name: Desonide
Synonyms: Prednacinolone;Desonide;D-2083;Steroderm
CAS NO.: 638-94-8
Molecular Formula: C24H32O6
Molecular Weight: 416.51
EINECS: 211-351-6
Assay: 99.5%
Melting point: 272-274°C
Storage temp.: Refrigerator
Appearance: White powder
Product Categories: Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals;Steroids;SPORANOX;Hormone Drugs.
Usage: 
(1)With acetal-based adrenal cortex hormones;
(2)Antifungal;
(3)Anti-inflammatory. Desonide has also been found as an impurity in budesonide (B689490).
How to use desonide topical: Use this medication only on the skin.
 
Desonide Description:
 
Desonide Ointment, 0.05% contains Desonide (Pregna - 1,4 - diene - 3,20 - dione,11,21 - dihydroxy - 16,17 - [(1 - methylethylidene)bis(oxy)] - ,(11β,16α)) a synthetic corticosteroid for topical dermatologic use. The corticosteroids constitute a class of primary synthetic steroids used topically as anti-inflammatory and antipruritic agents.
 
Chemically, Desonide, the active ingredient in Desonide Ointment, 0.05% is C24H32O6. It has the following structural formula:
 
The molecular weight of Desonide is 416.51. It is a white to off-white powder. The solubility of Desonide in distilled water saturated with ether is 184 mg/L.
Each gram of Desonide Ointment, 0.05% contains 0.5 milligram of Desonide microdispersed in a base of white petrolatum.
 
Desonide Application:
 
Desonide belongs to the group of medications known as topical corticosteroids. It is used to Treat various skin conditions, including rashes. It works by reducing inflammation and itching.
 
Endogenous eczema clinical cure rate, the overall curative effect is distinct, and the low Incidence of adverse reactions, is a safe and effective external cortex hormone.
 
Wash your hands. Before applying the medication, clean and dry the affected area. Apply a thin film of the medication to the affected area and gently rub in, usually 2-3 times daily, or as directed by your doctor. If using the gel, apply the gel usually only 2 times daily. Do not bandage, wrap, or cover the area unless you are instructed to do so by your doctor. If used in the diaper area on an infant, do not use tight-fitting diapers or plastic pants.
 
After applying the medication, wash and dry your hands, unless you are using this medication to treat the hands. When applying this medication near the eyes, avoid getting it in the eyes because this may worsen or cause glaucoma, or cause irritation. Also, avoid getting this medication in the nose or mouth. If you get this medication in your eyes, nose, or mouth, rinse immediately with plenty of water.
 

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Pharmaceutical Raw Materials Elubiol Dichlorophenylimidazoldioxolan 67914-69-6

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Pharmaceutical Raw Materials Elubiol Dichlorophenylimidazoldioxolan 67914-69-6
 
Elubiol Basic Info.:
 
Product Name: Elubiol (Dichlorophenylimidazoldioxolan)
Synonyms: Elubiol; Dichlorophenylimidazoldioxolan
CAS: 67914-69-6
Molecular formula: C27H30Cl2N4O5
Molecular weight: 561.46
Quantity: 500Kgs stock inventory. 10 tons per month
Appearance white to off white crystalline powder
Identification of HPLC
Loss on drying 0.50%max
The heavy metal 20ppmmax
The purity of (HPLC) 99.00%min
Content (titrimetric) 99.0%-101.0%
Package: 25kg paperboard barrel
 
Elubiol Description:
 
New posaconazole is a novel imidazole fungicides could inhibit the fungal sterol biosynthesis, wheat, and other components of the changes of cell membrane lipid compounds. Killing of Candida albicans, Histoplasma, Blastomyces dermatitidis and Coccidioides immitis, to dandruff, sterilization and regulate the skin grease in the washing products.
 
The main structure and the new azole ketoconazole are exactly the same, only at the end of keto ester instead of ketoconazole in. The Pityrosporum ovale of dandruff, two is the most potent inhibitor. The new azole included in the INCI directory, list the EU cosmetics ingredients and the Ministry of "health standard Chinese names of raw materials of Cosmetics International Directory", can be legally used in cosmetics.
 

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Phenacetin Pharmaceutical Intermediates BP Grade Antipyretic Analgesic 62-44-2

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Phenacetin Pharmaceutical Intermediates BP Grade Antipyretic Analgesic 62-44-2
 
1. Phenacetin Quick Detail:
 
Product Name: Phenacetin
CAS: 62-44-2
EINECS Number: 200-533-0
Formula: C10H13NO2
MW: 179.2157
Density: 1.099g / cm3
Melting point: 133-138 °C
Boiling point: 355.1 °C at 760 mmHg
Flash Point: 168.5 °C
Water-soluble: 0.076 g / 100 mL
Vapor Pressure: 3.21E-05mmHg at 25 °C
Uses: Anti-inflammatory drugs
Assay: 99%
Appearance: White or almost white crystalline powder
 
2. Phenacetin Descriptions:
 
Phenacetin is a pain-relieving and fever-reducing drug, widely used from its introduction in 1887 until banned in the US by the FDA in 1983. Its use has declined because of its adverse effects, which include increased risk of certain cancers and kidney damage. It is metabolized into paracetamol, which replaced it in some over-the-counter medications following the ban on phenacetin.
 
3. Applications of Phenacetin:
 
Phenacetin was widely used until the third quarter of the twentieth century, often in the form of an "A.P.C." or aspirin-phenacetin-caffeine compound analgesic, as a remedy for fever and pain. An early formulation (1919) was Vincent's APC in Australia. However the U.S. Food and Drug Administration ordered the withdrawal of drugs containing phenacetin in November 1983, owing to its carcinogenic and kidney-damaging properties (Federal Register of October 5, 1983 (48 FR 45466)).
 
It was also banned in India.As a result some branded, previously phenacetin-based preparations continued to be sold, but with the phenacetin replaced by safer alternatives. A popular brand of phenacetin was Roche's Saridon, which was reformulated in 1983 to contain propyphenazone, paracetamol and caffeine. Coricidin was also reformulated without phenacetin. Paracetamol is a metabolite of phenacetin with similar analgesic and antipyretic effects, but the new formulation has not been found to have phenacetin's carcinogenicity.
 
Phenacetin is now being used as a cutting agent to adulterate cocaine in the UK and Canada, owing to the similar physical features of the two drugs.Due to low cost phenacetin is used for research into the physical and refractive properties of crystals. It is an ideal compound for this type of research.
 

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T3 Fat Loss Steroid 98% Liothyronine Sodium Herbal Weight Loss Powders 55-06-1

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T3 Fat Loss Steroid 98% Liothyronine Sodium Herbal Weight Loss Powders 55-06-1
Organic Herbal Weight Loss Powders For Tablet / Capsule Liothyronine Sodium 
 
Liothyronine Sodium Basic Info.
 
Product Name: Liothyronine Sodium
Alias : T3 Sodium Salt; T3,Na; Liothyronine Sodium; Liothyronine Sodium Salt; Cytomel T3 
CAS NO: 55-06-1
MF: C15H11I3NNaO4
MW: 672.96
Einecs No: 200-223-5
Purity: 99%
Melting point: 205°C (dec.)(lit.)
Alpha: 20°(c=2,alcohol/1.2N HCl)
Storage temp.: 2-8°C
Solubility: 4 M NH4OH in methanol: 125 g/5mL, clear, yellow-brown
Appearance: white to beige powder, almost tasteless.
Product Categories: Amino Acids & Derivatives;Intermediates & Fine Chemicals;Pharmaceuticals;Steroid and Hormone;Isolabel;Other APIs.
Usage: 
(1)One of the hormones produced by the thyroid gland that is involved in the maintenance of metabolic homeostasis. Also produced in peripheral tissues as the active metabolite of Thyroxine.
(2)Cytochrome P450 inhibitor, Ca antagonist, anesthetic (local)Product 
 
Liothyronine Sodium Description :
 
Triiodothyronine, also known as T3, is a thyroid hormone. It affects almost every physiological process in the body, including growth and development, metabolism, body temperature, and heart rate.
 
Production of T3 and its prohormone thyroxine (T4) is activated by thyroid-stimulating hormone (TSH), which is released from the pituitary gland. This pathway is regulated via a closed-loop feedback process: Elevated concentrations of T3, and T4 in the blood plasma inhibit the production of TSH in the pituitary gland. As concentrations of these hormones decrease, the pituitary gland increases production of TSH, and by these processes, a feedback control system is set up to regulate the amount of thyroid hormones that are in the bloodstream.
 
As the true hormone, the effects of T3 on target tissues are roughly four times more potent than those of T4.Of the thyroid hormone that is produced, just about 20% is T3, whereas 80% is produced as T4. Roughly 85% of the circulating T3 is later formed in the thyroid by removal of the iodine atom from the carbon atom number five of the outer ring of T4. In any case, the concentration of T3 in the human blood plasma is about one-fortieth that of T4. This is observed in fact because of the short half-life of T3, which is only 2.5 days.This compares with the half-life of T4, which is about 6.5 days.
 
Liothyronine Sodium Application:
 
High Purity Liothyronine sodium/Cytomel T3/3,3',5-triiodothyronine sodium/CAS No: 55-06-1 200-223-5 Weight Loss Powders
Liothyronine is the most potent form of thyroid hormone. Chemically, it is nearly identical to triiodothyronine (T3). As such, it acts on the body to increase the basal metabolic rate, affect protein synthesis and increase the body's sensitivity to catecholamines (such as adrenaline) by permissiveness. The thyroid hormones are essential to proper development and differentiation of all cells of the human body. These hormones also regulate protein, fat, and carbohydrate metabolism, affecting how human cells use energetic compounds.
In comparison to levothyroxine (T4), liothyronine has a faster onset of action as well as a shorter biological half-life, which may be due to less plasma protein binding to thyroxine-binding globulin and transthyretin.
 
Physicians can use this instead of or in addition to levothyroxine (T4) for patients undergoing thyroid withdrawal. When a patient has thyroid cancer or Graves' disease, ablation therapy with radioactive iodine can be used to remove any trace thyroid tissue. For 131I therapy to be effective, the trace thyroid tissue must be avid to iodine. The best method is to starve the tissue of iodine but this can lead to hypothyroid symptoms for the patient. Withdrawal from levothyroxine can be done but it takes six weeks of withdrawal for the remaining thyroid tissue to be completely starved. Six weeks is needed owing to levothyroxine's long half life. Six weeks can be inconvenient for the patient and delay treatment. Liothyronine instead can be taken and withdrawn from for two weeks to starve the thyroid tissue. This is much safer and more convenient than levothyroxine.
 

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6-Oxo Muscle Building Steroids 4-Androstene-3 to Increase Muscle Mass 2243-06-3

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6-Oxo Muscle Building Steroids 4-Androstene-3 to Increase Muscle Mass 2243-06-3
 
6-OXO Basic Info.
 
Product Name: 6-OXO
Alias: 4-androstene-3, 6, 17- trione; Androst-4-ene-3, 6, 17-trione; 4-Androstenetrione; 4-Androstenetriol
CAS: 2243-06-3
Molecular Weight: 300.39
Molecular Formula: C19H24O3
Melting Point: 223-224° C
Package: Foil bag or tin, or as you require
Properties: White powder
Usage: Steroid drug intermediates. Low Estrogen Levels. 
Payment: T/T, Western Union and Money Gram
Delivery: Within 12hours After Your Payment
Express: EMS, DHL, FedEx, etc(door-to-door) 
 
6-OXO Description:
 
6 OXO refer to the same chemical compound that is a steroidal testosterone booster/anti-aromatase agent. First identified in cow adrenal glands it was further found to be a natural metabolite of androstenedione metabolism in humans and most mammals. This makes 6 OXO a perfectly legal dietary supplement under the current DSHEA law and since it is not androgenic, not at all an anabolic steroid. What 6 OXO does is reduce an enzyme in the body that turns your testosterone into estrogen. By blocking this enzyme two major things happen, first it causes you to keep more of your testosterone and second, the body senses a lack of estrogen and causes the testes to release more testosterone.
 
6 OXO has been well studied in men and the original manufacturer of 6 OXO, Ergopharm Inc actually paid for quite a few studies in both men and rats. The most telling one was done by Incledon, which studied 6 OXO in doses of 300mg in healthy men, then measured the effects. The Incledon study found a boost of testosterone of about 200% with a slight reduction in estradiol, which means it was very effective at boosting testosterone while reducing estrogen. This was the first really well tested testosterone booster on the market.
 
Applications Of 6-OXO:
 
Study delivered a dose of 50 mg of 1-DHEA for 10 months with no serious adverse events reported.
1-DHEA was administered at a dose of 200 mg/day for 24 weeks with slight androgenic effects noted.
 

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