Pharmaceutical raw materials used in synthesizing new medications

chemical-categories

Canagliflozin 98%

Name

Canagliflozin

Synonyms

(1S)-1,5-Anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-D-glucitol

Molecular Formula

C24H25FO5S

Molecular Weight

444.52

CAS Registry Number

842133-18-0

Pale Yellow Solid

Canagliflozin is a sodium/glucose cotransporter 2 (SGLT2) inhibitor. Canagliflozin has been shown to dose dependently reduce calculated renal threshold for glucose excretion and increase urinary glucose excretion. Canagliflozin is a candidate for the treatment of type 2 diabetes and obesity.

 

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Cancer Treatment Steroid Hormone Drug Intermediates 68-96-2 17A-Hydroxyprogesterone

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Cancer Treatment Steroid Hormone Drug Intermediates 68-96-2 17A-Hydroxyprogesterone
 
17 Alpha Hydroxyprogesterone Basic Info.:
 
Product Name: 17A-hydroxyprogesterone
Synonyms: 17a-Hydroxypregn-4-ene-3,20-dione; 17-Alpha-Hydroxy-Progesterone; 17-alpha-hydroxypregn-4-ene-3,20-dione; 17alpha-Hydroxyprogesterone; 17-hydroxypregn-4-ene-3,20-dione; 4-Pregnen-17a-ol-3,20-dione; Hydroxyprogesterone; 17α-Hydroxy Progesterone
CAS RN.: 68-96-2
EINECS: 200-699-4
Molecular Weight: 330.4611
Molecular Formula: C21H30O3
Density: 1.15g/cm3
Melting Point(ºC): 276ºC
Boiling Point(ºC): 482.9°C at 760 mmHg
Flash Point(ºC): 259.9°C
refractive_index: 1.56
 
17 Alpha Hydroxyprogesterone Description:
 
The hormone 17-hydroxyprogesterone is a building block for producing the hormone cortisol. Cortisol is produced mainly by the adrenal cortex (the outer part of the two adrenal glands, located above the kidneys). Cortisol is called the "stress hormone" because it's secreted in larger amounts as part of the body's response to physical or emotional stress.In kids, the most common cause of cortisol deficiency, and consequently high levels of 17-hydroxyprogesterone, is one of the forms of the genetic disorder congenital adrenal hyperplasia (CAH).
 
17 Alpha Hydroxyprogesterone Appication:
 
17-hydroxyprogesterone is elevated in patients with congenital adrenal hyperplasia (CAH). CAH is a group of autosomal recessive diseases characterized by a deficiency of cortisol and an excess of ACTH concentration. 17-hydroxyprogesterone is also useful in monitoring cortisol replacement therapy and in evaluating infertility and adrenal and ovarian neoplasms.
 

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Cancer related antigens BST-2 (126-134) LAB GRADE 97%

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