Pharmaceutical raw materials used in synthesizing new medications

chemical-categories

Enbucrilate

Enbucrilate a cyanoacrylate ester, is a butyl ester of 2-cyano-2-propenoic acid.Its chief use is as the main component of medical cyanoacrylate glues. It is also used for embolization of cerebral arteriovenous malformations before their surgical treatment,used to treat bleeding gastric varices.

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Enoxaparin Sodium USP 95%

Enoxaparin Sodium is a kind of low molecular weight heparin sodium salt,heparin sodium was benzyl esterized and product was depolymerized under basic condition in the end resulted in Enoxaparin Sodium.Now available information show that majority of the components have a 4-enoxpyranose structure at the end of undergraded chain,15%-25% of the component has a 1,6 anhydride at he end of the degraded chain.

Enoxaparin Sodium is the sodium salt of a depolymerized heparin. It is obtained by alkaline depolymerization of heparin benzyl ester. The starting material, heparin, is obtained exclusively from porcine intestinal mucosa. Enoxaparin Sodium consists of a complex set of oligosaccharides that have not yet been completely characterized.
The weight-average molecular weight of Enoxaparin Sodium is 4,500 Da, the range being between 3,800 and 5,000 Da; about 16 percent have a molecular weight of less than 2,000 Da, the range being between 12.0 and 20.0 percent; about 74 percent have a molecular weight between 2,000 and 8,000 Da, the range being between 68.0 and 82.0 percent. Not more than 18.0 percent have a molecular weight higher than 8,000 Da. When prepared as a solution, the solution is analyzed for clarity and degree of color using a validated method. The degree of sulfation is not less than 1.8 per disaccharide unit. It has a potency of not less than 90 and not more than 125 Anti-Factor Xa International Units (IU) per mg, and not less than 20.0 and not more than 35.0 Anti-Factor IIa IU per mg, calculated on the dried basis. The ratio of anti-factor Xa activity to anti-factor IIa activity is between 3.3 to 5.3.

Storage:Sealed,avoid light and oxygen resistant.

Application: 
Enoxaparin sodium is a blood thinner. It used to treat and prevent deep vein thrombosis and pulmonary embolism including during pregnancy. It is also used in those with acute coronary syndrome and heart attacks.Other uses include insidekidney dialysis machines.

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Entecavir FOOD GRADE 1

CBNumber: CB0506719
Chemical Name: ENTECAVIR
Molecular Formula: C12H15N5O3
Formula Weight: 277.283
CAS No.: 142217-69-4

 

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Eph-like receptor tyrosine kinase hEphB1b (422-432) LAB GRADE 97%

Creative peptides is specialized in the process development and the manufacturing of bioactive peptides. We offer custom peptide synthesis, process development, GMP manufacturing as well as catalog products. We supply Eph-like receptor tyrosine kinase hEphB1b (422-432).http://www.creative-peptides.com/product/eph-like-receptor-tyrosine-kinase-hephb1b-item-ta-115-5489.html

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Ephrin type-A receptor 3 (356-367) LAB GRADE 97%

Creative peptides is specialized in the process development and the manufacturing of bioactive peptides. We offer custom peptide synthesis, process development, GMP manufacturing as well as catalog products. We supply Ephrin type-A receptor 3 (356-367).http://www.creative-peptides.com/product/ephrin-type-a-receptor-item-ta-323-23042.html

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Epidermal growth factor receptor (478--488) LAB GRADE 97%

Creative peptides is specialized in the process development and the manufacturing of bioactive peptides. We offer custom peptide synthesis, process development, GMP manufacturing as well as catalog products. We supply Epidermal growth factor receptor (478--488).http://www.creative-peptides.com/product/epidermal-growth-factor-receptor-item-ta-555-31700.html

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Epithelial cell adhesion molecule (173-181) LAB GRADE 97%

Creative peptides is specialized in the process development and the manufacturing of bioactive peptides. We offer custom peptide synthesis, process development, GMP manufacturing as well as catalog products. We supply Epithelial cell adhesion molecule (173-181).http://www.creative-peptides.com/product/epithelial-cell-adhesion-molecule-item-ta-322-22688.html

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Eptifibatide Acetate LAB GRADE 96%

We provide Eptifibatide Acetate. More information please visit the website:http://www.creative-peptides.com/product/eptifibatide-acetate-item-10-101-15-48.html

CAT#
10-101-15
Synonyms/Alias
Eptifibatide; Integrilin; CHEBI:291902
CAS No.
148031-34-9 (net)
Sequence
3-Mercaptopropionyl-Homoarg-Gly-Asp-Trp-Pro-Cys-NH2 acetate salt (Disulfide bond)
M.W/Mr.
832.4
Molecular Formula
C35H49N11O9S2
Source
Synthetic
Long-term Storage Conditions
−20°C
Application
Eptifibatide is an inhibitor of platelet aggregation and belongs to the class of RGD (arginine-glycine-aspartate) mimetics. It reversibly inhibits platelet aggregation by preventing the binding of fibrinogen, von Willebrand factor and other adhesive ligands to the glycoprotein (GP) IIb/IIIa receptors.
Description
Eptifibatide, is an antiplatelet drug of the glycoprotein IIb/IIIa inhibitor class. Eptifibatide is a cyclic heptapeptide derived from a protein found in the venom of the southeastern pygmy rattlesnake (Sistrurus miliarius barbouri). It belongs to the class of the so-called RGD (arginine-glycine-aspartate)-mimetics and reversibly binds to platelets.
Areas of Interest
Antiplatelet drug

 

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Equilenin

Equilenin is a horse steroid. It is used as one of the components in Premarin.

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Equilin

Equilin is an estrogen from horses. It is one of the estrogens present in the mixture of estrogens isolated from horse urine and marketed as Premarin. Premarin became the most commonly used form of estrogen for hormone replacement therapy in the United States of America. Estrone is the major estrogen in Premarin and equilin is present as about 25% of the total. Estrone is a major estrogen that is normally found in women. Equilin is not normally present in women, so there has been interest in the effects of equilin on the human body.

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