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Chlorpheniramine Maleate, USP

Chlorpheniramine Maleate, USP is an active ingredient found in many prescription medications and over-the-counter products used for treating allergies, hives, and the common cold. It is part of a class of drugs called antihistamines. It blocks a specific type of histamine receptor in the body known as H1 receptors. Chlorpheniramine Maleate also blocks acetylcholine receptors, an action that produces some of the unpleasant side effects of the medication, such as dry mouth or difficulty urinating, but also helps to relieve a runny nose.

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Chlorphenoxamine

Chlorphenoxamine is an antihistamine and anticholinergic used as an antipruritic and antiparkinsonian agent.

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Chlorphentermine

Chlorphentermine is an appetite suppressant. Developed in 1962, it is the 4-chloro derivative of the better known appetite suppressant phentermine, which is still in current use. Chlorphentermine itself is a relatively weak stimulant with little abuse potential, but is classed as a Schedule III drug in the USA due mainly to its similarity to other appetite suppressants such as diethylpropion which have been more widely abused. It is no longer used due mainly to safety concerns, as it has a serotonergic effects profile similar to other withdrawn appetite suppressants such as fenfluramine and aminorex which were found to cause pulmonary hypertension and cardiac fibrosis following prolonged use.

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Chlorproethazine

Chlorproethazine is an antipsychotic.

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Chlorpromazine

Chlorpromazine is a typical antipsychotic. First synthesized on December 11, 1950, chlorpromazine was the first drug developed with specific antipsychotic action, and would serve as the prototype for the phenothiazine class of drugs, which later grew to comprise several other agents. The introduction of chlorpromazine into clinical use has been described as the single greatest advance in psychiatric care, dramatically improving the prognosis of patients in psychiatric hospitals worldwide. The availability of antipsychotic drugs curtailed indiscriminate use of electroconvulsive therapy and psychosurgery, and was one of the driving forces behind the deinstitutionalization movement.

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Chlorpropamide

Chlorpropamide is a drug in the sulphonylurea class used to treat type 2 diabetes mellitus. It is a long-acting sulphonylurea. It has more side effects than other sulphonylureas and its use is no longer recommended.

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Chlorprothixene

Chlorprothixene is a typical antipsychotic drug of the thioxanthene class and was the first of the series to be synthesized. It was introduced in 1959 by Lundbeck. Chlorprothixene is not approved for use in the United States.

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Chlorthalidone

Chlorthalidone is a diuretic drug used to treat hypertension. It is described as a thiazide diuretic. Compared with other medications of the thiazide class, chlorthalidone has the longest duration of action, but a similar diuretic effect at maximal therapeutic doses. It is often used in the management of hypertension and edema.

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Chlorzoxazone

Chlorzoxazone a synthetic compound, inhibits antigen-induced bronchospasms and, hence, is used to treat asthma and allergic rhinitis.It is used as an ophthalmic solution to treat conjunctivitis and is taken orally to treat systemic mastocytosis and ulcerative colitis.Chlorzoxazone is also a centrally-acting agent for painful musculoskeletal conditions.It inhibits degranulation of mast cells, subsequently preventing the release of histamine and slow-reacting substance of anaphylaxis (SRS-A), mediators of type I allergic reactions. Chlorzoxazone also may reduce the release of inflammatory leukotrienes.It may act by inhibiting calcium and potassium influx which would lead to neuronal inhibition and muscle relaxation.

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Cholecalciferol

Cholecalciferol is a form of vitamin D. It is structurally similar to steroids such as testosterone, cholesterol, and cortisol. It is used as additives in feed premixes. It is also used in pharmaceutical & cosmetic industry.

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