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Bifemelane is a pharmaceutical drug used in the treatment of senile dementia in Japan. It has nootropic, neuroprotective, and antidepressant effects, and acts through the cholinergic system in the brain. It is also useful for the treatment of glaucoma.


Bifonazole is an imidazole antifungal drug. It has dual mode of action. It blocks transformation of 24-methylendihydrolanosterol to desmethylsterol in fungi together with inhibition of HMG-CoA. This enables fungicidal properties against dermatophytes and distinguishes befonazole from other antifungal drugs.

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Bitolterol is a β2-adrenergic receptor agonist used for the relief of bronchospasm in conditions such as asthma and COPD.


Bopindolol is a beta blocker. It is an ester which acts as a prodrug for pindolol.

Boric Acid

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Bradykinin is an inflammatory mediator. It is a peptide that causes blood vessels to dilate (enlarge), and therefore causes blood pressure to fall. Bradykinin dilates blood vessels via the release of prostacyclin, nitric oxide, and Endothelium-Derived Hyperpolarizing Factor.Bradykinin is a physiologically and pharmacologically active peptide of the kinin group of proteins, consisting of nine amino acids.Bradykinin is a 9-amino acid peptide chain.Bradykinin is a potent endothelium-dependent vasodilator, leading to a drop in blood pressure. It also causes contraction of non-vascular smooth muscle in the bronchus and gut, increases vascular permeability and is also involved in the mechanism of pain. Bradykinin also causes natriuresis, contributing to the drop in blood pressure.Bradykinin raises internal calcium levels in neocortical astrocytes causing them to release glutamate.Bradykinin is also thought to be the cause of the dry cough in some patients on angiotensin-converting enzyme (ACE) inhibitor drugs. It is thought that bradykinin is converted to inactive metabolites by ACE, therefore inhibition of this enzyme leads to increased levels of bradykinin, which causes a dry cough via bronchoconstriction.

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Brecanavir is a protease inhibitor which has been studied for the treatment of HIV.

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Bromopride is a dopamine antagonist with prokinetic properties widely used as an antiemetic, closely related to metoclopramide. It appears to be safe and effective for use in pregnancy.

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Brotizolam is a sedative-hypnotic thienodiazepine drug which is a benzodiazepine analog. It possesses anxiolytic, anticonvulsant, hypnotic, sedative and skeletal muscle relaxant properties, and is considered to be similar in effect to short-acting benzodiazepines such as triazolam. It is used in the short term treatment of severe or debilitating insomnia. The drug was developed by a team led by T Nishiyama while working for Takeda Chemical Industries in 1976 in Japan.

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Bucindolol is a non-selective beta blocker with additional weak alpha-blocking properties and some intrinsic sympathomimetic activity. It was under review by the FDA in the United States for the treatment of heart failure in 2009 but was rejected.

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