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Carisbamate

Carisbamate is an experimental anticonvulsant drug under development by Johnson & Johnson Pharmaceutical Research and Development. A phase II clinical trial in the treatment of partial seizures demonstrated that the compound has efficacy in the treatment of partial seizures and a good safety profile. Since late 2006, the compound has been undergoing a large multicenter phase III clinical trial for the treatment of partial seizures. Its mechanism of action is unknown. On October 24, 2008, Johnson & Johnson announced that it had submitted a New Drug Application to the U.S. Food and Drug Administration for carisbamate.

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Carrageenan

Carrageenan is a common ingredient in many foods, such as milk products like yogurt or chocolate milk.Carrageenans are used in a variety of commercial applications as gelling, thickening, and stabilizing agents,food products, and in pharmaceutical formulations, cosmetics,mining.

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Cebaracetam

Cebaracetam is a drug from the racetam family.

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Cefamandole

Cefamandole is a second-generation broad-spectrum cephalosporin antibiotic. The clinically used form of cefamandole is the formate ester cefamandole nafate, a prodrug which is administered parenterally. Cefamandole has a broad spectrum of activity and can be used to treat bacterial infections of the skin, bones and joints, urinary tract, and lower respiratory tract.

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Chloroquine

Chloroquine is a 4-aminoquinoline drug used in the treatment or prevention of malaria.It is the prototype anti malarial drug, most widely used to treat all types of malaria except for disease caused by chloroquine resistant Plasmodium falciparum. It is highly effective against erythrocytic forms of Plasmodium vivax, Plasmodium ovale and Plasmodium malariae, sensitive strains of Plasmodium falciparum and gametocytes of Plasmodium vivax.Chloroquine inhibits the parasitic enzyme heme polymerase that converts the toxic heme into non-toxic hemazoin, thereby resulting in the accumulation of toxic heme within the parasite. It may also interfere with the biosynthesis of nucleic acids.

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Ciclazindol

Ciclazindol is an antidepressant and anorectic drug of the tetracyclic chemical class that was developed in the mid to late 1970s, but was never marketed. It acts as a norepinephrine reuptake inhibitor, and to a lesser extent as a dopamine reuptake inhibitor. It has no effects on the SERT, 5-HT receptors, mACh receptors, or α-adrenergic receptors, and has only weak affinity for the H1 receptor. As suggested by its local anesthetic properties, ciclazindol may also inhibit sodium channels. It is known to block potassium channels as well.

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Ciglitazone

Ciglitazone is a thiazolidinedione. It is considered the prototypical compound for the thiazolidinedione class. It was never used as a medication, but it sparked interest in the effects of thiazolidinediones. It significantly decreases VEGF production by human granulosa cells in an in vitro study, and may potentially be used in ovarian hyperstimulation syndrome. It is a potent and selective PPARγ ligand. It is active in vivo as an anti-hyperglycemic agent in the ob/ob murine model. Inhibits HUVEC differentiation and angiogenesis and also stimulates adipogenesis and decreases osteoblastogenesis in human mesenchymal stem cells.

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Cilansetron

Cilansetron is a drug that is a 5HT-3 antagonist. 5HT-3 receptors are responsible for causing many things from nausea to excess bowel movements. It is thought in conditions like irritable bowel syndrome the receptors have become faulty or oversensitive. 5HT-3 antagonists work by blocking the nervous and chemical signals from reaching these receptors.

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Cilnidipine

Cilnidipine is a calcium channel blocker.Cilnidipine is the novel calcium antagonist accompanied with L-type and N-type calcium channel blocking function. Cilnidipine is used for hypertension management.

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Cinitapride

Cinitapride is a gastroprokinetic agent and antiulcer agent of the benzamide class. It acts as an agonist of the 5-HT1 and 5-HT4 receptors and as an antagonist of the 5-HT2 receptors.

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