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TAPI-1 analytical pure 98%

TAPI-1 is a specific TACE (TNF-α-converting enzyme) inhibitor.

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YF-2 analytical pure 0.995

YF-2 is a highly selective and blood-brain-barrier permeable histone acetyltransferase activator, it acetylates H3 in the hippocampus. YF-2 interacts with CBP, PCAF and GCN5 with EC50s of 2.75 μM, 29.04 μM and 49.31 μM respectively and shows no effect on HDAC, it could be used in the treatment of cancer and Alzheimer's disease.

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7ACC2 analytical pure 0.995

7ACC2 is a potent MCT inhibitor with IC50 of 11 nM for inhibition of [14C]-lactate influx for antitumor treatment targeting lactate transport in cancer cells.

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ABT-737 analytical pure 98%

ABT-737 is a BH3 mimetic inhibitor of Bcl-xL, Bcl-2 and Bcl-w with EC50 of 78.7 nM, 30.3 nM and 197.8 nM, respectively, showing no inhibition observed against Mcl-1, Bcl-B or Bfl-1.

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AMZ30 analytical pure 0.993

AMZ30 is a selective, covalent inhibitors of protein phosphatase methylesterase-1 (PME-1; IC50=600 nM), and selectively inactivates PME-1 and reduces the demethylated form of PP2A in living cells.

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AZD4547 analytical pure 98%

AZD4547 is a selective FGFR inhibitor targeting FGFR1/2/3 with IC50 of 0.2 nM/2.5 nM/1.8 nM with weaker activity against FGFR4, VEGFR2 (KDR), and little activity observed against IGFR, CDK2, and p38.

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AZD5582 analytical pure 98%

AZD5582 is a class of dimeric Smac mimetics as potent IAP antagonist and binds potently to the BIR3 domains of cIAP1, cIAP2, and XIAP (IC50 = 15, 21, and 15 nM, respectively).

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Bupivacaine Hydrochloride

Bupivacaine Hydrochloride is a racemate composed of equimolar amounts of dextrobupivacaine hydrochloride and levobupivacaine hydrochloride. Bupivacaine Hydrochloride is a long-acting, amide-type local anesthetic.

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DMH-1 analytical pure 0.998

DMH-1 is a potent and selective BMP inhibitor with IC50s of 27/107.9/< 5 nM for ALK1/2/3 respectively and inactive on ALK5, BMPR2, AMPK and VEGFR2.

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EC330 analytical pure 0.988

EC330 is an inhibitor of leukemia inhibitory factor (LIF).

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