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Epirubicin

Epirubicin is an anthracycline drug used for chemotherapy. Similarly to other anthracyclines, epirubicin acts by intercalating DNA strands. Intercalation results in complex formation which inhibits DNA and RNA synthesis. It also triggers DNA cleavage by topoisomerase II, resulting in mechanisms that lead to cell death. Binding to cell membranes and plasma proteins may be involved in the compound's cytotoxic effects. It also generates free radicals that cause cell and DNA damage. It is primarily used against breast and ovarian cancer, gastric cancer, lung cancer, and lymphomas.

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Eprosartan

Eprosartan is an angiotensin II receptor antagonist used for the treatment of high blood pressure. The drug acts on the renin-angiotensin system in two ways to decrease total peripheral resistance. First, it blocks the binding of angiotensin II to AT1 receptors in vascular smooth muscle, causing vascular dilatation. Second, it inhibits sympathetic norepinephrine production, further reducing blood pressure.

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Esketamine

Esketamine is a general anaesthetic of the dissociative class by way of the central nervous system and has its mode of action as an NMDA receptor antagonist. It is the (S)-enantiomer of ketamine, which is the more active constituent chirality out of the dual (RS) mixed chiral variety in which ketamine is most often prepared.

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Etanercept

Etanercept s an injectable medication prescribed to treat patients with autoimmune disorders.Etanercept is a fusion protein produced through expression of recombinant DNA. That is, it is a product of a DNA "construct" engineered to link the human gene for soluble TNF receptor 2 to the gene for the Fc component of human immunoglobulin G1 (IgG1).

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Etofibrate

Etofibrate is a fibrate. It is a combination of clofibrate and niacin, linked together by an ester bond. In the body, clofibrate and niacin separate and are released gradually, in a manner similar to controlled-release formulations.

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Etoricoxib

Etoricoxib is a COX-2 selective inhibitor. It is prescribed for the treatment of rheumatoid arthritis, psoriatic arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and gout.

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Etravirine

Etravirine belongs to a class of medications known as non-nucleoside reverse transcriptase inhibitors (NNRTIs). It is used in the treatment of the human immunodeficiency virus (HIV), which can progress and lead to the acquired immune deficiency syndrome (AIDS) if not properly treated.The most common side effects of Intelence include:Skin rashes,Changes in distribution of body fat,Immune reconstitution syndrome,Tingling, numbness or pain in the hands or feet

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Everolimus

Everolimus is a derivative of Rapamycin (sirolimus), and works similarly to Rapamycin as an mTOR (mammalian target of rapamycin) inhibitor. It is currently used as an immunosuppressant to prevent rejection of organ transplants.

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Febuxostat

Febuxostat belongs to a group of drugs known as xanthine oxidase (XO) inhibitors. It is used to reduce blood uric acid levels in patients with gout, a painful arthritic condition that mainly affects the big toe, but can also affect the ankles, heels, knees, elbows, wrists or fingers.Febuxostat is used in the treatment of gout patients with hyperuricemia, or high uric acid levels.The most common side effects of Uloric are liver problems,nausea,joint pain.

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Felodipine

Felodipine is a long-acting 1,4-dihydropyridine calcium channel blocker (CCB)b. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. By inhibiting the influx of calcium in smooth muscle cells, felodipine prevents calcium-dependent myocyte contraction and vasoconstriction. Felodipine is the most potent CCB in use and is unique in that it exhibits fluorescent activity. In addition to binding to L-type calcium channels, felodipine binds to a number of calcium-binding proteins, exhibits competitive antagonism of the mineralcorticoid receptor, inhibits the activity of calmodulin-dependent cyclic nucleotide phosphodiesterase, and blocks calcium influx through voltage-gated T-type calcium channels. Felodipine is used to treat mild to moderate essential hypertension.

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