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EC330 analytical pure 0.988

EC330 is an inhibitor of leukemia inhibitory factor (LIF).

KNK437 analytical pure 0.99

KNK437 is a pan-HSP inhibitor, which inhibits the synthesis of inducible HSPs, including HSP105, HSP72, and HSP40.

MK-1064 analytical pure 97%

MK-1064 is a selective orexin 2 receptor antagonist(2-SORA) for the research of insomnia.

PZ-2891 analytical pure 98%

PZ-2891 is a specific and brain-permeable Pantothenate kinase (PANK) modulator, acting as an orthosteric inhibitor with IC50 of 1.3 nM for hPANK3 and also an allosteric activator of PANK3 activity in the presence of acetyl-CoA in biochemical assays.

SEW2871 analytical pure 98%

SEW2871 is a potent and selective sphingosine-1-phosphate 1 (S1P1) receptor agonist. Activates S1P1 receptor with an EC50 of 13 nM, but does not activate S1P2, S1P3, S1P4 or S1P5 receptors at concentrations up to 10 μM. Cell-permeable and active in vivo.

VX-765 analytical pure 0.99

VX-765 is a potent and selective inhibitor of caspase-1 with Ki of 0.8 nM in a cell-free assay.

WZ811 analytical pure 0.989

WZ811 is a small molecular and potency CXCR4 antagonist with EC50 of 0.3 nM.

AT9283 analytical pure 0.996

AT9283 is a multi-targeted inhibitor with IC50s of 4, 1.2, 1.1 and approximate 3 nM for Bcr-Abl (T315I), JAK2 and JAK3, Aurora A and Aurora B, respectively.

AZ3451 analytical pure 0.985

AZ3451 is a protease-activated receptor-2 (PAR2) antagonist.

AZD1480 analytical pure 0.99

AZD1480 is a selective ATP-competitive JAK1/2 inhibitor with IC50 value of 1.3 and <0.4 nM, respectively, as well as shows inhibitory effect on JAK3 and Tyk2.

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