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Nelfinavir is a potent HIV protease inhibitor. It is used in combination with other antiviral drugs in the treatment of HIV in both adults and children.Nelfinavir inhibits the HIV viral proteinase enzyme which prevents cleavage of the gag-pol polyprotein, resulting in noninfectious, immature viral particles.Side effects include thirst and hunger, unexplained weight loss, increased urination, fatigue, and dry, itchy skin.
Nesiritide is used to improve breathing in people with congestive heart failure (CHF).
Nevirapine is a potent, non-nucleoside reverse transcriptase inhibitor used in combination with nucleoside analogues for treatment of HIV infection and AIDS.Nevirapine binds directly to reverse transcriptase (RT) and blocks the RNA-dependent and DNA-dependent DNA polymerase activities by causing a disruption of the enzyme's catalytic site. The activity of nevirapine does not compete with template or nucleoside triphosphates.Symptoms of overdose include edema, erythema nodosum, fatigue, fever, headache, insomnia, nausea, pulmonaryinfiltrates, rash, vertigo, vomiting, and weight decrease.
Nifenazone is a drug used for joint and muscular pain.
Nimesulide is a relatively COX-2 selective, non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties.It is a sulphonanilide analogue.Its approved indications are the treatment of acute pain, the symptomatic treatment of osteoarthritis and primary dysmenorrhoea in adolescents and adults above 12 years old.It acts by inhibiting the release of tumour necrosis factor-alpha, acts as a competitive inhibitor of histamine release and reduces superoxide anion formation. It is absorbed rapidly and completely after oral administration. Nimesulide is proved safe and effective in the treatment of a wide range of inflammatory and painful conditions, including osteoarthritis, extra-articular disorders such as tendinitis and bursitis, post-operative pain, primary dysmenorrhoea.
Nizofenone is a psychostimulant/nootropic. It has been shown to have neuroprotective effects and protects neurons from death following cerebral anoxia. It might thus be useful in the treatment of acute neurological conditions such as stroke.
Nonivamide is an organic compound and a capsaicinoid. It is an amide of pelargonic acid and vanillylamine. It is present in chili peppers, but is commonly manufactured synthetically. It is more heat-stable than capsaicin. It is used as a food additive to add pungency to seasonings, flavorings, and spice blends. It is also used in the confectionary industry to create a hot sensation, and in the pharmaceutical industry in some formulations as a cheaper alternative to capsaicin.
Norbornene is a bridged cyclic hydrocarbon. The molecule consists of a cyclohexene ring bridged with a methylene group in the para position. The molecule carries a double bond which induces significant ring strain and significant reactivity. It is utilized to make pharmaceutical intermediates, pesticide compounds, specialty fragrances and in general organic synthesis. When combined with ethylene, norbornene will react and turn into a cyclic olefin copolymer.Polynorbornene is used mainly in the rubber industry for anti-vibration, anti-impact and grip improvement.
Norcocaine is a minor metabolite of cocaine. It is the only confirmed pharmacologically active metabolite of cocaine, although salicylmethylecgonine is also speculated to be an active metabolite.
Nordazepam is a 1,4-benzodiazepine derivative. Like other benzodiazepine derivatives, it has anticonvulsant, anxiolytic, muscle relaxant and sedative properties. However, it is used primarily in the treatment of anxiety. It is an active metabolite of diazepam, chlordiazepoxide, clorazepate, prazepam, pinazepam, and medazepam.
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