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Ornidazole is a drug that cures some protozoan infections. It is used by the poultry industry. It has been investigated for use in Crohn's disease after bowel resection.
Orthocaine is a local anesthetic.
Oxilorphan is an opioid antagonist from the morphinan family of drugs. It is a non-selective opioid which is a μ antagonist but a κ partial agonist. It has similar effects to naloxone, and around the same potency as an antagonist. It has some weak partial agonist effects and can produce hallucinogenic effects at high doses, suggesting some kappa opioid agonist action. It was trialled for the treatment of opiate addiction, but was not developed commercially.
Oxiracetam is a nootropic drug of the racetam family. Oxiracetam is a much less studied drug that is more aggressive in onset and effect then Aniracetam. Oxiracetam is a possible cognitive enhancer. It is safe in most models, however extremely high dosing of this drug in mice over prolonged periods caused loss of bladder control in one study. Oxiracetam is well absorbed from the gastrointestinal tract with a bioavailability of 68-82%.
Oxybutynin is an anticholinergic medication used to relieve urinary and bladder difficulties, including frequent urination and inability to control urination, by decreasing muscle spasms of the bladder. It competitively antagonizes the M1, M2, and M3 subtypes of the muscarinic acetylcholine receptor.
Oxymatrine is used in the treatment of cervical cancer, gastric cancer, liver and gallbladder,antibacterial anti-inflammatory drugs.
Paroxetine is an SSRI antidepressant. It is used to treat major depression, obsessive-compulsive disorder, panic disorder, social anxiety, and generalized anxiety disorder in adult outpatients.
Pefloxacin is a quinolone drug used to treat bacterial infections. Pefloxacin has not been approved for use in the United States.Pefloxacin was developed in 1979 and approved in France for human use in 1985.Pefloxacin has been increasingly used as a veterinary medicine to treat microbial infections.Pefloxacin is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria. It functions by inhibiting DNA gyrase, a type II topoisomerase, and topoisomerase IV, which is an enzyme necessary to separate, replicated DNA, thereby inhibiting cell division.
Phenazepam is a benzodiazepine drug, which was developed in the Soviet Union and now produced in Russia and some CIS countries. It is used in the treatment of neurological disorders such as epilepsy, alcohol withdrawal syndrome and insomnia. It can be used as a premedication before surgery as it augments the effects of anesthetics and reduces anxiety.
Phenformin is an anti-diabetic drug from the biguanide class. It was withdrawn from most markets in the late 1970s due to a high risk of lactic acidosis, which was fatal in 50% of cases. It was discovered in 1957 by Ungar, Freedman and Seymour Shapiro, working for the US Vitamin Corporation. Clinical trials began in 1958 which showed it to be effective but with gastrointestinal side effects.
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