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Thiouracil

Thiouracil is a white crystalline compound,that interferes with the synthesis of thyroxine, It is used to reduce the action of the thyroid gland, especially in the treatment of hyperthyroidism.

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Tianeptine

Tianeptine is a drug used for treating major depressive episodes. It has structural similarities to the tricyclic antidepressants, but it has different pharmacological properties. Until recently, it has been assumed that tianeptine is a selective serotonin reuptake enhancer, opposite to the action of SSRIs. However, newer studies question this hypothesis; one review suggests that long-term administration of tianeptine has no effect on serotonin pathways, while another still points to the cancellative effects of tianeptine and fluoxetine coadministration on serotonin reuptake. Tianeptine enhances the extracellular concentration of dopamine in the nucleus accumbens and modulates the D2 and D3 dopamine receptors, but this effect is modest and almost certainly indirect. There is also action on the NMDA and AMPA receptors. Recent reviews point to this pathway as a hypothesized mechanism of action, based on tianeptine's effect of promoting stress-associated impaired neuroplasticity.

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Ticagrelor

Ticagrelor is an oral antiplatelet treatment for acute coronary syndromes (ACS) in a new chemical class called cyclopentyltriazolopyrimidines (CPTPs). Ticagrelor works by preventing the formation of new blood clots and maintaining blood flow in the body to help reduce a patient's risk of another cardiovascular event (called atherothrombotic events) such as a heart attack or cardiovascular death. Ticagrelor is the first reversibly-binding oral adenosine diphosphate (ADP) receptor antagonist. Ticagrelor is extensively metabolized in humans with approximately 27% of the dose excreted as the parent compound.

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Tipifarnib

Tipifarnib is a farnesyltransferase inhibitor that is being investigated in patients 65 years of age and older with newly diagnosed acute myeloid leukemia. It is also being tested in clinical trials in patients in certain stages of breast cancer.

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Tipranavir

Tipranavir is a nonpeptidic protease inhibitor. It is administered with ritonavir in combination therapy to treat HIV infection. It has the ability to inhibit the replication of viruses that are resistant to other protease inhibitors and it recommended for patients who are resistant to other treatments. Resistance to tipranavir itself seems to require multiple mutations. Side effects of tipranavir can be more severe than other anti-retrovirals. Some side effects include intracranial hemorraging, hepatitis, and diabetes mellitus. The drug has also been shown to cause increases in total cholesterol and triglycerides.

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Tiratricol

Tiratricol is a thyroid hormone analogue. It is indicated in the management of thyroid hormone resistance syndrome and is used, in combination with levothyroxine, to suppress thyroid-stimulating hormone production in patients with thyroid cancer. It has been investigated for use in reducing goiter. It has also shown some effectiveness in reducing the atrophy caused when using corticosteroids.

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Tizanidine

Tizanidine is a drug that is used as a muscle relaxant. It is a centrally acting α-2 adrenergic agonist. It is used to treat the spasms, cramping, and tightness of muscles caused by medical problems such as multiple sclerosis, spastic diplegia, back pain, or certain other injuries to the spine or central nervous system. It is also prescribed off-label for migraine headaches, as a sleep aid, and as an anticonvulsant. It is also prescribed for some symptoms of fibromyalgia.

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Tocopherol

Tocopherols are a class of chemical compounds of which many have vitamin E activity. It is a series of organic compounds consisting of various methylated phenols. The compound α-tocopherol, a common form of tocopherol added to food products. Tocotrienols, which are related compounds, also have vitamin E activity. All of these various derivatives with vitamin activity may correctly be referred to as "vitamin E." Tocopherols and tocotrienols are fat-soluble antioxidants but also seem to have many other functions in the body.

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Tolazamide

Tolazamide is an oral blood glucose lowering drug used for people with Type 2 diabetes. It is part of the sulfonamide family.

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Tolonidine

Tolonidine is an antihypertensive.

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