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Vitasmooth

Vitasmooth is a highly compactable and organoleptically pleasing formulation of calcium carbonate specifically designed for incorporation into nutritional supplements. Vitasmooth is ideal for the formulation of both calcium and calcium and vitamin supplements manufactured by direct compression.

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Vorinostat

Vorinostat (rINN) or suberoylanilide hydroxamic acid (SAHA), is a drug currently under investigation for the treatment of cutaneous T cell lymphoma (CTCL), a type of skin cancer, to be used when the disease persists, gets worse, or comes back during or after treatment with other medicines. It is the first in a new class of agents known as histone deacetylase inhibitors. A recent study suggested that vorinostat also possesses.

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Xipranolol

Xipranolol is a beta blocker.

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Zatosetron

Zatosetron is a drug which acts as an antagonist at the 5HT3 receptor. It is orally active and has a long duration of action, producing antinauseant effects but without stimulating the rate of gastrointestinal transport. It is also an effective anxiolytic in both animal studies and human trials, although with some side effects at higher doses.

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Zestoretic

Zestoretic combines an angiotensin converting enzyme inhibitor, lisinopril, and a diuretic, hydrochlorothiazide. It was sustained for at least 24 hours. Zestoretic is indicated for the treatment of hypertension.

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Zidovudine

Zidovudine is a nucleoside analog reverse transcriptase inhibitor, a type of antiretroviral drug used for the treatment of HIV/AIDS. It is an analog of thymidine.It is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA during reverse transcription. It improves immunologic function, partially reverses the HIV-induced neurological dysfunction, and improves certain other clinical abnormalities associated with AIDS. Its principal toxic effect is dose-dependent suppression of bone marrow, resulting in anemia and leukopenia.Zidovudine is phosphorylated to active metabolites that compete for incorporation into viral DNA and inhibit the HIV reverse transcriptase enzyme competitively and act as a chain terminator of DNA synthesis.The lack of a 3'-OH group in the incorporated nucleoside analogue prevents the formation of the 5' to 3' phosphodiester linkage essential for DNA chain elongation, and therefore, the viral DNA growth is terminated.

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Zometapine

Zometapine is an antidepressant drug which is a pyrazolodiazepine derivative. Its molecular structure closely resembles benzodiazepines and is unrelated to other antidepressant drug classes.

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Zonisamide

Zonisamide is a sulfonamide anticonvulsant approved for use as an adjunctive therapy in adults with partial-onset seizures.It may be a carbonic anhydrase inhibitor although this is not one of the primary mechanisms of action. Zonisamide may act by blocking repetitive firing of voltage-gated sodium channels leading to a reduction of T-type calcium channel currents, or by binding allosterically to GABA receptors,thereby inhibit the uptake of the inhibitory neurotransmitter GABA while enhancing the uptake of the excitatory neurotransmitter glutamate.

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amifostine

Amifostine is a cytoprotective adjuvant used in cancer chemotherapy and radiotherapy involving DNA-binding chemotherapeutic agents. Amifostine is also indicated to reduce the incidence of xerostomia in patients undergoing radiotherapy for head and neck cancer.

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