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Doxazosin

Doxazosin, a quinazoline compound is an alpha blocker used to treat high blood pressure and urinary retention associated with benign prostatic hyperplasia. It is an alpha-1 adrenergic receptor blocker that inhibits the binding of norepinephrine to the alpha-1 receptors on the membrane of vascular smooth muscle cells. The primary effect of this inhibition is relaxed vascular smooth muscle tone, which decreases peripheral vascular resistance, leading to decreased blood pressure.

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Doxazosin Mesylate

Doxazosin Mesylate is a medication used in the treatment of high bloodstream pressure and signs and symptoms of harmless prostatic hyperplasia. It stops norepinephrine that's revealed by nerve fibres from joining to alpha-1 receptors on simple muscle tissue adjoining veins and in the prostate as well as bladder. By preventing the result of norepinephrine, Doxazosin relaxes the particular smooth muscle tissue. Relaxation in the smooth muscle tissue surrounding veins leads to them to expand (dilate) as well as thereby decreases bloodstream pressure. Relaxation of smooth muscle tissue in the prostate as well as bladder increases the circulation of urine along with decreases the discomfort and pain characteristic of BPH.

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Doxefazepam

Doxefazepam is a drug which is a benzodiazepine derivative. It possesses anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties. It is used therapeutically as a hypnotic.

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Doxepin

Doxepin is a dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation.It also possesses anticholinergic activity and modulates antagonism of histamine H(1)- and H(2)-receptors.The mechanism of action of doxepin is not completely understood. It is thought that Like amitriptyline, doxepin enhances the actions of norepinephrine and serotonin by blocking their reuptake at the neuronal membrane. Doxepin may also act on histamine H1-receptors, resulting in sedative effects, and beta-adrenergic receptors.Symptoms include cardiac dysrhythmias, severe hypotension, convulsions, and CNS depression, including coma. Changes in the electrocardiogram, particularly in QRS axis or width, are clinically significant indicators of tricyclic a

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Doxifluridine

Doxifluridine is a fluorinated pyrimidine nucleoside, which displays cytostatic activity. It is known that this compound is the inactive form of 5-Fluorouridine, which is converted by enzymes in vivo.

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Doxorubicin

Doxorubicin is a drug used in cancer chemotherapy. It is an anthracycline antibiotic, closely related to the natural product daunomycin, and like all anthracyclines, it works by intercalating DNA. It is commonly used in the treatment of a wide range of cancers, including hematological malignancies, many types of carcinoma, and soft tissue sarcomas. Doxorubicin's most serious adverse effect is life-threatening heart damage.

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Doxycycline

Doxycycline, a long-acting tetracycline derived from oxytetracycline, is used to inhibit bacterial protein synthesis and treat non-gonococcal urethritis and cervicitis, exacerbations of bronchitis in patients with COPD, and adult periodontitis.Doxycycline, like minocycline, is lipophilic and can pass through the lipid bilayer of bacteria. Doxycycline reversibly binds to the 30 S ribosomal subunits and possibly the 50S ribosomal subunit(s), blocking the binding of aminoacyl tRNA to the mRNA and inhibiting bacterial protein synthesis

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Doxylamine Succinate

Doxylamine Succinate is used in allergies and as an antitussive, antiemetic, and hypnotic. Doxylamine has also been administered in veterinary applications and was formerly used in parkinsonism.Like other antihistamines, doxylamine acts by competitively inhibiting histamine at H1 receptors. It also has substantial sedative and anticholinergic effects.Signs of overdose include wheezing, tightness in the chest, fever, itching, bad cough, blue skin color, fits, swelling of face, lips, tongue, or throat.

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Dronedarone

Dronedarone is a drug, mainly for the indication of cardiac arrhythmias. It is used for the treatment of atrial fibrillation and atrial flutter in patients whose hearts have either returned to normal rhythm or who undergo drug therapy or electric shock treatment to maintain normal rhythm. A trial of the drug in heart failure was stopped as an interim analysis showed a possible increase in heart failure deaths, in patients with moderate to severe CHF.

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Drospirenone

Drospirenone is a synthetic progestin that is an analog to spironolactone.As such it has anti-mineralocorticoid properties, counteracts the estrogen-stimulated activity of the renin-angiotensin-aldosterone system, and is not androgenic.Progestins such as drospirenone diffuse freely into target cells in the female reproductive tract, mammary gland, hypothalamus, and the pituitary and bind to the progesterone receptor. Once bound to the receptor, progestins slow the frequency of release of gonadotropin releasing hormone (GnRH) from the hypothalamus and blunt the pre-ovulatory LH surge.

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