Buy pharmaceutical chemicals online | pharmaceutical chemicals manufacturers | pharmaceutical chemicals suppliers - Worldofchemicals


SD-208 analytical pure 0.997

SD-208 is a potent, orally active ATP-competitive transforming growth factor-β receptor 1 (TGF-βRI) inhibitor (IC50= 49 nM) and displays > 100-fold and > 17-fold selectivity over TGF-βRII and other common kinases respectively.

SH-4-54 analytical pure 0.99

SH-4-54 is a potent, small molecule, nonphosphorylated STAT3 inhibitor with KD of 300 nM and 464 nM for STAT3 and STAT5, respectively.

SMI-4a analytical pure 0.996

SMI-4a is a potent inhibitor of Pim1 with IC50 of 17 nM, modestly potent to Pim-2, does not significantly inhibit any other serine/threonine- or tyrosine-kinases.

VE-821 analytical pure 0.994

VE-821 is a potent and selective ATP competitive inhibitor of ATR with Ki/IC50 of 13 nM/26 nM.

VE-822 analytical pure 0.999

VE-822 is an ATR inhibitor with IC50 of 19 nM in HT29 cells.

Yoda 1 analytical pure 0.999

Yoda 1 is a Piezo1 channel activator.

ABT-199 analytical pure 0.999

ABT-199 is a Bcl-2-selective inhibitor with Ki of < 0.01 nM, > 4800-fold selective versus Bcl-xL and Bcl-w, and showing no activity to Mcl-1.

ABT-263 analytical pure 0.993

ABT-263 is a potent inhibitor of Bcl-xL, Bcl-2 and Bcl-w with Ki of ≤ 0.5 nM, ≤1 nM and ≤1 nM in cell-free assays, but binds more weakly to Mcl-1 and A1.

AZD0156 analytical pure 0.999

AZD0156 is a potent and selective inhibitors of ATM kinase, with potential chemo-/radio-sensitizing and antineoplastic activities.

AZD1080 analytical pure 0.999

AZD1080 is a selective, orally active, brain permeable GSK3 inhibitor of GSK3α and GSK3β with Ki of 6.9 nM and 31 nM, respectively, shows > 14-fold selectivity against CDK2, CDK5, CDK1 and Erk2.

Suppliers uses cookies to ensure that we give you the best experience on our website. By using this site, you agree to our Privacy Policy and our Terms of Use. X