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Laropiprant

Laropiprant is used in combination with niacin to reduce blood cholesterol. Laropiprant itself has no cholesterol lowering effect, but it reduces facial flushes induced by niacin.

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Latanoprost

Latanoprost ophthalmic solution is a topical medication used for controlling the progression of glaucoma or ocular hypertension, by reducing intraocular pressure. It is a prostaglandin analogue that works by increasing the outflow of aqueous fluid from the eyes.Latanoprost is a prostaglandin F2a analogue. Specifically, Latanoprost is a prostanoid selective FP receptor agonist that is believed to reduce the intraocular pressure (IOP) by increasing the outflow of aqueous humor.Symptoms of overdose include bloodshot eyes and eye irritation.

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Lauric Acid

Lauric acid is a saturated fatty acid with a 12-carbon atom chain. In the laboratory, lauric acid is often used to investigate the molar mass of an unknown substance via the freezing-point depression. It has been claimed to have antimicrobial properties.

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Levorphanol

Levorphanol is an opioid medication used to treat severe pain. It is the laevorotary stereoisomer of the synthetic morphinan (Dromoran) and a pure opioid agonist, first described in Germany in 1948 as an orally active morphine-like analgesic. It has the same properties as morphine with respect to the potential for habituation, tolerance, physical dependence and withdrawal syndrome. It is 4 to 8 times as potent as morphine and has a longer half-life. It has affinity to μ, κ, and δ opioid receptors, but lacks complete cross-tolerance with morphine. The duration of action is generally long compared to other comparable analgesics, and varies from 4 hours to as much as 15 hours. For this reason levorphanol is useful in palliation of chronic pain and similar conditions. Its NMDA actions, similar to those of the phenylheptylamine open-chain narcotics such as methadone and ketobemidone, make levorphanol useful for types of pain that other analgesics may not be as effective against; levorphanol's sigma receptor, SNRI properties make it even more useful particularly for neuropathic pain.

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Lifitegrast

Lifitegrast is an FDA approved drug indicated for the treatment of signs and symptoms of dry eye, a syndrome called keratoconjunctivitis sicca.Lifitegrast inhibits an integrin, lymphocyte function-associated antigen 1 (LFA-1), from binding to intercellular adhesion molecule 1 (ICAM-1). This mechanism down-regulates inflammation mediated by T lymphocytes.

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Liraglutide

Liraglutide is a long-acting glucagon-like peptide-1 (GLP-1) analog that has been developed by Novo Nordisk for the treatment of type 2 diabetes.Victoza lowers blood sugar by stimulating the pancreas to secrete insulin, effectively helping the body use insulin more efficiently when blood sugar levels are elevated.

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Lofepramine

Lofepramine is a third generation tricyclic antidepressant which was introduced in 1983 for the treatment of depressive disorders. It is partially converted to its active metabolite desipramine in vivo. However, it is unlikely this property plays a substantial role in its overall effects as lofepramine exhibits lower toxicity and anticholinergic side effects relative to desipramine while retaining equivalent antidepressant efficacy.

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Lomevactone

Lomevactone is a psychostimulant and antidepressant drug which was synthesized and studied in the 1980s, but was never marketed.

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Lopirazepam

Lopirazepam is a short-acting benzodiazepine analog of the pyridodiazepine type with anxiolytic and hypnotic properties. It has never been marketed.

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Loreclezole

Loreclezole is a sedative and an anticonvulsant which acts as a GABA agonist. It binds allosterically to the GABAA receptor. The binding site of loreclezole has been shown experimentally to be shared by valerenic acid, an extract of the root of the valerian plant.

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