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Spiradoline

Spiradoline is a drug which acts as a highly selective κ-opioid agonist. It has analgesic, diuretic and antitussive effects, and produces subjective effects in animals similar to those of ketocyclazocine and allylnormetazocine. The main effect in humans is sedation, along with analgesic and diuretic effects, but significant side effects such as dysphoria and hallucinations have stopped it from being used clinically. Kappa-agonists have been shown to react negatively with the Mu-receptor, instead of having an assumed synergy since they are both opiate receptors, such as with the Mu and Delta receptors.

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Stiripentol

Stiripentol is an anticonvulsant drug used in the treatment of epilepsy. It is unrelated to other anticonvulsants and belongs to the group of aromatic allylic alcohols.

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Succinimide

Succinimide is a cyclic imide. Succinimides are used as anticonvulsant drugs, including ethosuximide, phensuximide, and methsuximide. These are also used to form covalent bonds between proteins or peptides and plastics.

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Sulconazole

Sulconazole is an antifungal medication of the imidazole class. It is available as a cream or solution to treat skin infections such as athlete's foot, ringworm, jock itch, and sun fungus.

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Sulfonamide

Sulfonamide is a sulfonyl group connected to an amine group. Sulfonamide is also the basis of several groups of drugs. Sulfonamide drugs were the first antibiotics to be used systemically, and paved the way for the antibiotic revolution in medicine. The first sulfonamide, trade-named Prontosil, was a prodrug.Sulfonamides are prepared by the reaction of a sulfonyl chloride with ammonia or an amine.

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Tannic Acid

Tannic Acid is a type of polyphenol. It is a specific commercial form of tannin. It is usually extracted from Caesalpinia spinosa, Rhus semialata, Quercus infectoria, Rhus coriaria plant parts. It is a common mordant used in the dyeing process for cellulose fibers, leather production, to treat diarrhea.

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Tasimelteon

Tasimelteon is a drug approved by the U.S. Food and Drug Administration for the treatment of non-24-hour sleep-wake disorder. Tasimelteon is a selective agonist for the melatonin receptors MT1 and MT2.Tasimelteon (previously known as BMS-214,778) was developed for the treatment of insomnia and other sleep disorders.

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Tebanicline

Tebanicline is a drug which acts as a partial agonist at neuronal nicotinic acetylcholine receptors, binding to both the α3β4 and the α4β2 subtypes.

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Telcagepant

Telcagepant is an investigational drug for the acute treatment and prevention of migraine. In the acute treatment of migraine, it was found to have equal potency to rizatriptan and zolmitriptan in two Phase III clinical trials.

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Telmisartan

Telmisartan is an angiotensin II receptor antagonis used in the management of hypertension. Telmisartan is an angiotensin II receptor blocker that shows high affinity for the angiotensin II receptor type 1 (AT1), with a binding affinity 3000 times greater for AT1 than AT2.Telmisartan works by blocking the vasoconstrictor and aldosterone secretory effects of angiotensin II. Telmisartan does not inhibit the angiotensin converting enzyme, other hormone receptors, or ion channels.

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