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Tebanicline

Tebanicline is a drug which acts as a partial agonist at neuronal nicotinic acetylcholine receptors, binding to both the α3β4 and the α4β2 subtypes.

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Telcagepant

Telcagepant is an investigational drug for the acute treatment and prevention of migraine. In the acute treatment of migraine, it was found to have equal potency to rizatriptan and zolmitriptan in two Phase III clinical trials.

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Telmisartan

Telmisartan is an angiotensin II receptor antagonis used in the management of hypertension. Telmisartan is an angiotensin II receptor blocker that shows high affinity for the angiotensin II receptor type 1 (AT1), with a binding affinity 3000 times greater for AT1 than AT2.Telmisartan works by blocking the vasoconstrictor and aldosterone secretory effects of angiotensin II. Telmisartan does not inhibit the angiotensin converting enzyme, other hormone receptors, or ion channels.

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Terbutaline

Terbutaline is a β2-adrenergic receptor agonist. Terbutaline is currently used to delay preterm labor for 48 hours to allow for fetal lung maturity through steroid injections. It should not be used to prevent preterm labor or delay labor past 48-72 hours. Terbutaline is used as a fast-acting bronchodilator (often used as a short-term asthma treatment) and as a tocolytic to delay premature labor. It is used for prevention and reversal of bronchospasm in patients 12 years of age and older with reversible, obstructive airway disease, as well as symptomatic management of reversible bronchospasm associated with bronchitis and emphysema and also used acute IV and sub-Q therapy in selected women to inhibit uterine contractions in preterm labor (tocolysis) and prolong gestation when beneficial.

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Tesofensine

Tesofensine is a serotonin–noradrenaline–dopamine reuptake inhibitor from the phenyltropane family of drugs, which is being developed for the treatment of obesity.

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Theobromine

Theobromine is a bitter xanthine alkaloid of the cacao, plantisomer of theophylline, as well as paraxanthine. Theobromine is the primary alkaloid found in cocoa and chocolate. Theobromine is used as a vasodilator (a blood vessel widener), a diuretic (urination aid), and heart stimulant. Theobromine is an isomer of theophylline, as well as paraxanthine. Theobromine was first discovered in 1841 in cacao beans by Russian chemist Alexander Voskresensky. Theobromine has also been used in birth defect experiments involving mice and rabbits. Theobromine is known to induce gene mutations in lower eukaryotes and bacteria. Theobromine is weaker in both its inhibition of cyclic nucleotide phosphodiesterases and its antagonism of adenosine receptors.

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Thioanisole

Thioanisole has a wide range of applications in organic synthesis as solvents as well as reagents. It is also involved in versatile in the synthesis of specific compound classes include agricultural chemical, property-enhancing additives, pharmacological drugs, chemical resistant polymers, detergents, and rubber antioxidants.

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Thiothixene

Thiothixene is a typical antipsychotic drug of the thioxanthene class used in the treatment of psychoses like schizophrenia. It was introduced in 1965 by Pfizer.

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Tiamenidine

Tiamenidine is a compound that shares a lot of the pharmacological properties of clonidine.

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Ticlopidine

Ticlopidine is an antiplatelet drug in the thienopyridine family. Like clopidogrel, it is an adenosine diphosphate receptor inhibitor. It is used in patients in whom aspirin is not tolerated, or in whom dual antiplatelet therapy is desirable. Because it has been reported to increase the risk of thrombotic thrombocytopenic purpura and neutropenia, its use has largely been supplanted by the newer drug, clopidogrel, which is felt to have a much lower hematologic risk.

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