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p-Anisidine

p-Anisidine is the least toxic of the three isomers of anisidine but still causes blood damages upon oral ingestion, inhalation or skin contact. If heated strongly, it may release very toxic fumes of nitrogen oxides. p-Anisidine is used as intermediaries in the production of azo-dyes and pharmaceuticals.

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varenicline

Varenicline  is a prescription medication used to treat nicotine addiction. Varenicline is a nicotinic receptorpartial agonist—it stimulates nicotine receptors more weakly than nicotine itself does. In this respect it is similar to cytisine and different from the nicotinic antagonistbupropion, and nicotine replacement therapies (NRTs) like nicotine patches and nicotine gum. As a partial agonist it both reduces cravings for and decreases the pleasurable effects of cigarettes and other tobacco products. Through these mechanisms it can assist some patients to quit smoking...

2,3-Xylidine

2,3-Xylidine is an important raw material of producing anti-in-flammatory Mefenamic Acid.It also can be used in the production of dyes, pesticides.

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2,6-Lutidine

2,6-Lutidine is a natural heterocyclic aromatic organic compound and it  has been evaluated for use as a food additive owing to its nutty aroma when present in solution at very low concentrations.

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2-Butylfuran

2-Butylfuran is a clear colourless compound used mainly as flavouring agents. It is widely used in snacks food and seasoning.

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2-Ethylfuran

2-Ethylfuran is a colorless compound with sweet burnt earthy malty odor ,widely used as flavoring agents.

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3-Bromofuran

3-Bromofuran is a clear yellow-to-brown liquid with an aromatic odor.It is used as a solvent for refining lubricating oils and butadiene extraction. It is used as a fungicide and weed killer. It is used in the production of tetrahydrofuran (THF).Niitro-substituted furan derivatives are used as biocides or fungicides to inhibit bacterial growth.

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8-Azaguanine

8-Azaguanine is a purine analog. It functions as an antimetabolite and is easily incorporated into ribonucleic acids. It shows antineoplastic activity and has been used in the treatment of acute leukemia. 8-Azaguanine was the first purine analogue discovered to inhibit experimental tumors in mice.

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AZD1152-HQPA

AZD1152-HQPA is an active metabolite of Barasertib which is a novel acetanilide-substituted pyrazole-aminoquinazoline prodrug that is converted rapidly to the active drug AZD-1152 hydroxy-QPA (AZD1152-HQPA) in human plasma. AZD1152-HQPA is a specific inhibitor of the enzymatic activity of Aurora kinase, with selectivity for Aurora B (IC50 of 0.37 nM versus 1368 nM for Aurora B and A kinases, respectively); the inhibitor had even less activity against a panel of greater than 50 other serine-threonine and tyrosine kinases including FLT3, JAK2, and Abl.

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Acenaphthene

Acenaphthene is a polycyclic aromatic hydrocarbon (PAH) consisting of naphthalene with an ethylene bridge connecting positions 1 and 8. An alternative name, 1,2-dihydroacenaphthylene, emphasizes that it is a hydrogenated form of acenaphthylene. It is a constituent of coal tar.Acenaphthene was prepared the first time from coal tar by Marcellin Berthelot and after that with Bardy he synthesized it from a-ethyl naphthalene. It is used in preparation of dyes, pesticides and pharmaceuticals.It does not appear to be carcinogenic.

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