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AZD7762 analytical pure 0.999

AZD7762 is a potent and selective inhibitor of Chk1 with IC50 of 5 nM, being equally potent against Chk2 and less potent against CAM, Yes, Fyn, Lyn, Hck and Lck.

AZD8186 analytical pure 0.999

AZD8186 is an isoform-specific small-molecule PI3K inhibitor, potently inhibits PI3Kβ (IC50=4 nM) and PI3Kδ (IC50=12 nM) with selectivity over PI3Kα (IC50=35 nM) and PI3Kγ (IC50=675 nM).

Amitriptyline Hydrochloride

Amitriptyline Hydrochloride is an antidepressant with sedative effects. Its mechanism of action in man is not known. Amitriptyline Hydrochloride is not a monoamine oxidase inhibitor and it does not act primarily by stimulation of the central nervous system.

BLU9931 analytical pure 0.999

BLU9931 is an inhibitor of FGFR4 with IC50 of 3 nM and is less potent for FGFR1/2/3 (IC50 > 150 nM).

BMN-673 analytical pure 0.999

BMN-673 is a PARP1/2 inhibitor with IC50 of 0.57 nM for PARP1.

BSI-201 analytical pure 0.978

BSI-201 is a PARP1 inhibitor with demonstrated effectiveness in triple-negative breast cancer (TNBC).

Beclomethasone Dipropionate

Beclomethasone Dipropionate is a steroid ester comprising beclomethasone having propionyl groups at the 17- and 21-positions. It has a role as an anti-inflammatory drug, an anti-asthmatic drug, a prodrug and an anti-arrhythmia drug.

CAL-101 analytical pure 0.999

CAL-101 is a selective p110δ inhibitor with IC50 of 2.5 nM, shown to have 40- to 300-fold greater selectivity for p110δ than p110α/β/γ, and 400- to 4000-fold selectivity to p110δ than C2β, hVPS34, DNA-PK and mTOR.

Ciprofloxacin Hydrochloride

Ciprofloxacin Hydrochloride is the hydrochloride salt form of ciprofloxacin, a fluoroquinolone related to nalidixic acid with antibacterial activity. Ciprofloxacin hydrochloride exerts its bactericidal effect by interfering with the bacterial DNA gyrase.

EPZ005687 analytical pure 98%

EPZ005687 is a potent inhibitor of PRC2 with IC50 value of 54±5nM (measured by PRC2 enzymatic activity), with selectivity >500-fold over other HMTs, ~50-fold over EZH1. EPZ005687 can specifically inhibit H3K27 methylation.

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