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Bicalutamide

Bicalutamide is an oral non-steroidal anti-androgen used in the treatment of prostate cancer and hirsutism. Bicalutamide acts as a pure anti-androgen by binding to the androgen receptor (AR) and preventing the activation of the AR and subsequent upregulation of androgen responsive genes by androgenic hormones. Bicalutamide is indicated for the treatment of stage D2 metastatic prostate cancer in combination with a luteinizing hormone-releasing hormone analogue or as a monotherapy. It has also been used in clinical trials for ovarian cancer. It has also been used in combination with castration. Bicalutamide is currently tested for treatment of andogen receptor positive metastatic breast cancer.

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Bietaserpine

Bietaserpine is a derivative of reserpine used as an antihypertensive agent.

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Bleomycin A2

Bleomycin A2 is used as the representative structure for Bleomycin.

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Brinzolamide

Brinzolamide is a carbonic anhydrase inhibitor used to lower intraocular pressure in patients with open-angle glaucoma or ocular hypertension. Brinzolamide is a highly specific inhibitor of CA-II, which is the main CA isoenzyme involved in the secretion of aqueous humor. Brinzolamide can decrease intraocular pressure by approximately 16-19% in patients with elevated intraocular pressure.

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Bulbocapnine

Bulbocapnine is an alkaloid found in Corydalis and Dicentra, herbs in the family Fumariaceae that can cause fatal poisoning in sheep and cattle. It has been shown to act as an acetylcholinesterase inhibitor, and inhibits biosynthesis of dopamine via inhibition of the enzyme tyrosine hydroxylase. It has been used in the treatment of muscular tremors and vestibular nystagmus.

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Butabarbital

Butabarbital is in a class of medications called barbiturates. Butabarbital, a barbiturate, is used for the treatment of short term insomnia. It belongs to a group of medicines called central nervous system (CNS) depressants that induce drowsiness and relieve tension or nervousness. It works by slowing activity in the brain.

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Butoconazole

Butoconazole is an imidazole antifungal used in gynecology.

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Butylparaben

Butylparaben is one of the parabens. It is the butyl ester of p-hydroxybenzoic acid and is used as an antifungal preservative in cosmetics. It is also a component of many medications in the form of suspension fluid.

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Butyric Acid

Butyric Acid is an organic compound that is responsible for the smell of butter that has gone sour. Butyric Acid is a substance that was isolated from butter in 1869. It is also known as butanoic acid or butyrate. Butyric acid, a four-carbon fatty acid, is formed in the human colon by bacterial fermentation of carbohydrates (including dietary fiber), and putatively suppresses colorectal cancer (CRC). It has diverse and apparently paradoxical effects on cellular proliferation, apoptosis and differentiation that may be either pro-neoplastic or anti-neoplastic, depending upon factors such as the level of exposure, availability of other metabolic substrate and the intracellular milieu. Butyric acid is a medium-strong acid that reacts with bases and strong oxidants, and attacks many metals. It is a carboxylic acid, as defined by the COOH group. Butyric acid is prepared on a large scale by the fermentation of starch or sugar. It is found most commonly in butter, but can also be present in some fruits. Butyric acid is also produced synthetically, through fermentation of various carbohydrates, to be used as a flavoring agent in various food products. It is also used for the production of plastics, plasticizers, surfactants and textile auxiliaries. Butyric acid and its derivatives are also being seriously considered around the world as potential anticancer agents.

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Caffeic Acid

Caffeic acid is a hydroxycinnamic acid, a naturally occurring organic compound. It consists of both phenolic and acrylic functional groups. It is found in all plants because it is a key intermediate in the biosynthesis of lignin, one of the principal sources of biomass. It is known as an antioxidant in vitro and also in vivo. It shows immunomodulatory and antiinflammtory activity. It may be the active ingredient in caffenol, a do-it-yourself black and white photographic developer made from instant coffee. It is also used as a matrix in MALDI mass spectrometry analyses.

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