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Clomocycline is a tetracycline antibiotic that inhibits bacterial cell growth by inhibiting translation. It is lipophilic and easily diffuses across cell membranes or enters cells via porin channels in the bacterial membrane. It binds to the 30S ribosomal subunit and prevents the aminoacyl tRNA from binding to the A site of the ribosome-RNA complex. Clomocycline binding is reversible in nature. It may be used to treat acne, gum disease, and other bacterial infections such as chalmydia, brucellosis, bartonellosis and cholera. It is also effective against certain strains of malaria and may also be prescribed for the treatment of Lyme disease.
Clopenthixol is a typical antipsychotic drug of the thioxanthene class. It was introduced by Lundbeck in 1961. It is a racemic mixture of cis and trans isomers. Zuclopenthixol, the pure cis isomer, was later introduced by Lundbeck in 1962, and has been much more widely used. Both drugs are equally effective as antipsychotics and have similar adverse effect profiles, but clopenthixol is half as active on a milligram-to-milligram basis and appears to produce more sedation in comparison.
Cloperastine is a cough suppressant that acts on the central nervous system.
Cloroqualone is an analogue of methaqualone developed in the 1980s and marketed mainly in France and some other European countries. It has sedative and antitussive properties, and was sold either alone or in combination with other ingredients as a cough medicine. It has weaker sedative properties than methaqualone and was sold for its useful cough-suppressing effects, but was withdrawn from the French market in 1994 because of concerns about its potential for abuse and overdose.
Clotrimazole is an antifungal medication commonly used in the treatment of fungal infections of both humans and animals such as vaginal yeast infections, oral thrush, and ringworm. It is also used to treat athlete's foot and jock itch.
Cocaethylene is the ethyl ester of benzoylecgonine. It is structurally similar to cocaine, which is the methyl ester of benzoylecgonine. It is formed in vivo when cocaine and ethyl alcohol have been ingested simultaneously. It is a recreational drug with stimulant, euphoriant, anorectic, sympathomimetic and local anesthetic properties. Three monoamine neurotransmitters known as serotonin (5-HT), norepinephrine (NE), and dopamine (DA) play an important role in cocaethylene's action. Cocaethylene increases the level of serotonergic, noradrenergic, and dopaminergic neurotransmission by inhibiting the action of the serotonin transporter (SERT), norepinephrine transporter (NET), and dopamine transporter (DAT) which makes cocaethylene a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI).
Cocoa Butter it is used to produce milk chocolate, some of which contains more cocoa butter than chocolate liquor. Cocoa butter was also used in coloring peanut butter (see false advertising). Because of the low melting point of cocoa butter, it is often used in pharmaceuticals as a base for suppositories. It is typically solid at room temperature, but readily melts at body temperature, releasing the medication. Cocoa butter is one of the most stable fats known, containing natural antioxidants that prevent rancidity and give it a storage life of two to five years, making it a good choice for non-food products. The smooth texture, sweet fragrance and emollient property of cocoa butter make it a popular ingredient in cosmetics and skin care products, such as soaps and lotions. The moistur
corn oil is used in soap, salve, paint, rustproofing for metal surfaces, inks, textiles, nitroglycerin, and insecticides. It is sometimes used as a carrier for drug molecules in pharmaceutical preparations.
Crospovidone is a water-insoluble synthetic cross-linked homo-polymer of N-vinyl-2-pyrrolidinone.The unique structure of Crospovidone provides superior adsorptive capacity and exceptional swelling rate. This renders it an excellent tablet disintegrant and functional excipient in novel delivery systems.
Cyclandelate is a vasodilator used in the treatment of claudication, arteriosclerosis and Raynaud's disease. It is also used to treat night time leg cramps,and has been investigated for its effect against migraine. It is orally administered.
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