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Cycloheptane is a cycloalkane. It is used as a nonpolar solvent for the chemical industry and as an intermediate in the manufacture of chemicals and pharmaceutical drugs. It may be derived by Clemmensen reduction from cycloheptanone. Cycloheptane vapour is irritating to the eyes and may cause respiratory depression if inhaled in large quantity.
Cyclosporine is a cyclic undecapeptide from an extract of soil fungi. It is a powerful immunosupressant with a specific action on T-lymphocytes. It is used for the prophylaxis of graft rejection in organ and tissue transplantation.Cyclosporine binds to cyclophillin. The complex then inhibits calcineurin which is normally responsible for activating transcription of interleukin 2. Cyclosporine also inhibits lymphokine production and interleukin release. Cyclosporine emulsion is thought to act as a partial immunomodulator in patients whose tear production is presumed to be suppressed due to ocular inflammation associated with keratoconjunctivitis sicca.
Delafloxacin is a fluoroquinolone antibiotic. It is more active than other quinolones against Gram-positive bacteria such as MRSA.
Desomorphine is an opiate analogue invented in 1932 in the United States, that is a derivative of morphine, where the 6-hydroxy group has been removed and the 7,8 double bond has been saturated. It has sedative and analgesic effects, and is around 10 times more potent than morphine. It was described as having a fast onset and a short duration of action, with relatively little nausea or respiratory depression compared to equivalent doses of morphine. This drug has attracted recent attention in Russia due to an upsurge in clandestine production, presumably due to its relatively simple synthesis from codeine. It is prepared from α-chlorocodide, which is itself obtained by reacting thionyl chloride with codeine. By catalytic reduction, α-chlorocodide gives dihydrodesoxycodeine, which yields desomorphine on demethylation.
Panthenol is the alcohol analog of pantothenic acid, and is thus a provitamin of B5. In organisms it is quickly oxidized to pantothenate. Panthenol comes in two enantiomers, D and L. Only D-panthenol is biologically active, however both forms have moisturizing properties. For cosmetic use, panthenol comes either in D form, or as a racemic mixture of D and L.
Dichlorophen is an anticestodal agent. It is used as an algicide, bactericide and agricultural fungicide. It is also used as an ingredient in deodorants, shampoos, soaps and cosmetics.
Diclofensine is a stimulant drug which acts as a triple monoamine reuptake inhibitor, primarily inhibiting the reuptake of dopamine and noradrenaline. It was found to be an effective antidepressant in human trials, with relatively few side effects, but was ultimately dropped from clinical development, possibly due to concerns about its abuse potential.
Diethylamine is chemically classified as a secondary amine with strong ammonia-like odor containing the organic compound. The secondary amine having the formula C4H11N. Diethylamine has various uses in a wide variety of commercial products. Buy Diethylamine from Zhejiang Jianye Chemical Co., Ltd. to get the best quality chemicals offered by the top supplier of industrial chemicals.
Dimethocaine is a local anesthetic with stimulant properties that some studies have shown to be one-tenth the potency of cocaine. Anecdotal user reports indicate no euphoria and only mild stimulating effects. Other users fail to perceive of any recreational effects whatsoever. The drug however still presents strain on the cardiovascular systems, like cocaine, with the potential to induce tachycardia which could be problematic for those who continuously redose. Additional reports of respiratory arrest have been noted.
Drospirenone is a synthetic progestin that is an analog to spironolactone.As such it has anti-mineralocorticoid properties, counteracts the estrogen-stimulated activity of the renin-angiotensin-aldosterone system, and is not androgenic.Progestins such as drospirenone diffuse freely into target cells in the female reproductive tract, mammary gland, hypothalamus, and the pituitary and bind to the progesterone receptor. Once bound to the receptor, progestins slow the frequency of release of gonadotropin releasing hormone (GnRH) from the hypothalamus and blunt the pre-ovulatory LH surge.
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