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Elsamitrucin is a drug used in chemotherapy.


Elvitegravir is an investigational new drug for the treatment of HIV infection. It acts as an integrase inhibitor. It is undergoing Phase III clinical trial conducted by the pharmaceutical company Gilead Sciences, which licensed EVG from Japan Tobacco in March 2008.

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Enilospirone is a selective 5-HT1A receptor agonist of the azapirone class.


Enzalutamide is an orally bioavailable, organic, non-steroidal small molecule targeting the androgen receptor (AR) with potential antineoplastic activity. It blocks androgens from binding to the androgen receptor and prevents nuclear translocation and co-activator recruitment of the ligand-receptor complex. It also induces tumour cell apoptosis, and has no agonist activity. Early preclinical studies also suggest that MDV3100 inhibits breast cancer cell growth.

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Eplivanserin was an experimental drug for the treatment of insomnia which was being developed by Sanofi Aventis. Sanofi Aventis announced in December 2009 that it was withdrawing its application for approval of eplivanserin from both the U.S. Food and Drug Administration and the European Medicines Agency.


Eptifibatide is synthetic cyclic hexapeptide that binds to platelet receptor glycoprotein and inhibits platelet aggregation.Eptifibatide was not lethal to rats, rabbits, or monkeys when administered by continuous intravenous infusion .

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Esomeprazole is a proton pump inhibitor which is used in the treatment of dyspepsia, peptic ulcer disease, gastroesophageal reflux disease and Zollinger-Ellison syndrome. It is the S-enantiomer of omeprazole. It is a proton pump inhibitor which reduces acid secretion through inhibition of ATPase in gastric parietal cells.Esomeprazole is combined with the antibiotics clarithromycin and amoxicillin in the 7-14 day eradication triple therapy for Helicobacter pylori.

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Esreboxetine is a selective norepinephrine reuptake inhibitor which was under development by Pfizer for the treatment of neuropathic pain and fibromyalgia but failed to show significant benefit over currently available medications and was discontinued. It is the (+)-(S,S)-enantiomer of reboxetine and is even more selective in comparison.

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Ethosuximide useful in the treatment of absence seizures unaccompanied by other types of seizures.Acute overdoses may produce nausea, vomiting, and CNS depression including coma with respiratory depression

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Famprofazone is a non-steroidal anti-inflammatory agent of the pyrazolone series. It has analgesic, anti-inflammatory, and antipyretic effects. It has been known to produce methamphetamine as an active metabolite, with 15-20% of an oral dose being converted to it. As a result, famprofazone has occasionally been implicated in causing false positives on drug tests for amphetamines.

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