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Metaclazepam is a drug which is a benzodiazepine derivative. It is a relatively selective anxiolytic with less sedative or muscle relaxant properties than other benzodiazepines such as diazepam or bromazepam. It has an active metabolite N-desmethylmetaclazepam, which is the main metabolite of metaclazepam. There is no significant difference in metabolism between younger and older individuals.


Metheptazine is an opioid analgesic from the phenazepine family. It produces similar effects to other opioids, including analgesia, sedation, dizziness and nausea.


Methopholine is an opioid analgesic drug invented in the 1960s. It is an isoquinoline derivative which is not structurally related to most other opioids. It has around the same efficacy as an analgesic as codeine, and was evaluated for the treatment of postoperative pain. The drug was withdrawn from the market in 1965 due to the occurance of ophthalamic side-effects and the discovery that it could produce corneal opacities in dogs.


Methotrexate is an antimetabolite and antifolate drug. It is used in treatment of cancer, autoimmune diseases, ectopic pregnancy, and for the induction of medical abortions. It acts by inhibiting the metabolism of folic acid. It is used as a treatment for some autoimmune diseases including: rheumatoid arthritis, psoriasis, psoriatic arthritis, lupus and Crohn's disease. It has also been used for multiple sclerosis but is not approved by the Food and Drug Administration. Methotrexate anti-tumor activity is a result of the inhibition of folic acid reductase, leading to inhibition of DNA synthesis and inhibition of cellular replication.

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Microcolin A

Microcolin A, a marine-derived compound, has been shown to be a novel antiproliferative and immunosuppressive agent.


Misonidazole is a radiosensitizer used in radiation therapy to cause normally resistant hypoxic tumor cells to become sensitive to the treatment.


Mocetinostat is a benzamide histone deacetylase inhibitor undergoing clinical trials for treatment of various cancers including follicular lymphoma, Hodgkin's lymphoma and acute myelogenous leukemia.

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Mofebutazone is a drug used for joint and muscular pain. It is a 3,5-pyrazolinedione derivative.


Monosulfiram is an ectoparasiticide used in the treatment and prevention of scabies. It is usually sold as a solution or medicated soap, sometimes in combination with benzyl benzoate.

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Moxifloxacin is a synthetic fluoroquinolone antibiotic agent. Bayer AG developed the drug and it is marketed worldwide (as the hydrochloride) under the brand name Avelox (in some countries also Avalox) for oral treatment.The bactericidal action of moxifloxacin results from inhibition of the enzymes topoisomerase II (DNA gyrase) and topoisomerase IV. DNA gyrase is an essential enzyme that is involved in the replication, transcription and repair of bacterial DNA. Topoisomerase IV is an enzyme known to play a key role in the partitioning of the chromosomal DNA during bacterial cell division. Symptoms of overdose include CNS and gastrointestinal effects such as decreased activity, somnolence, tremor, convulsions, vomiting, and diarrhea.

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