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Microcolin A, a marine-derived compound, has been shown to be a novel antiproliferative and immunosuppressive agent.
Misonidazole is a radiosensitizer used in radiation therapy to cause normally resistant hypoxic tumor cells to become sensitive to the treatment.
Mocetinostat is a benzamide histone deacetylase inhibitor undergoing clinical trials for treatment of various cancers including follicular lymphoma, Hodgkin's lymphoma and acute myelogenous leukemia.
Mofebutazone is a drug used for joint and muscular pain. It is a 3,5-pyrazolinedione derivative.
Monosulfiram is an ectoparasiticide used in the treatment and prevention of scabies. It is usually sold as a solution or medicated soap, sometimes in combination with benzyl benzoate.
Moxifloxacin is a synthetic fluoroquinolone antibiotic agent. Bayer AG developed the drug and it is marketed worldwide (as the hydrochloride) under the brand name Avelox (in some countries also Avalox) for oral treatment.The bactericidal action of moxifloxacin results from inhibition of the enzymes topoisomerase II (DNA gyrase) and topoisomerase IV. DNA gyrase is an essential enzyme that is involved in the replication, transcription and repair of bacterial DNA. Topoisomerase IV is an enzyme known to play a key role in the partitioning of the chromosomal DNA during bacterial cell division. Symptoms of overdose include CNS and gastrointestinal effects such as decreased activity, somnolence, tremor, convulsions, vomiting, and diarrhea.
Naloxonazine is an irreversible mu opioid antagonist.
Neticonazole is an imidazole antifungal for the treatment of fungal skin infections.
Nifuroxazide is an oral nitrofuran antibiotic, patented since 1966 and used to treat colitis and diarrhea in humans and non-humans.
Nitazoxanide is a synthetic nitrothiazolyl-salicylamide derivative and an antiprotozoal agent. It is used for the treatment of infectious diarrhea caused by Cryptosporidium parvum and Giardia lamblia in patients 1 year of age and older. It is currently in Phase II clinical trials for the treatment of hepatitis C, in combination with peginterferon alfa-2a and ribavirin.
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