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Isonicotinic Acid

Isonicotinic acid is an organic compound with a carboxyl group on a pyridine ring. It is an isomer of nicotinic acid.It is chiefly used in antituberculosis drugs especially Isoniazid, the most effective one. Isonicotinic acid and its derivatives are used in manufacturing pharmaceuticals and agrochemicals.

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Isonipecotic Acid

Isonipecotic acid is a heterocyclic compound which acts as a GABA receptor partial agonist. It consists of a piperidine ring with a carboxylic acid moiety in the iso position.

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Isopropyl Isocyanate

Isopropyl Isocyanate is used in the synthesis for the target molecules such as pharmaceuticals, pesticides, textile softener, lubricants and industrial disinfectants.They are used as plastic additives and as heat treatment salt formulations for metals.

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Isosorbide Mononitrate

Isosorbide mononitrate is a drug used principally in the treatment of angina pectoris, hypertension, and myocardial infarction and acts by dilating the blood vessels so as to reduce the blood pressure. It is an active metabolite of isosorbide dinitrate and exerts qualitatively similar effects. Isosorbide mononitrate reduces the workload of the heart by producing venous and arterial dilation. Isosorbide mononitrate is primarily metabolized by the liver, but unlike oral isosorbide dinitrate. It is cleared by denitration to isosorbide and glucuronidation as the mononitrate, with 96% of the administered dose excreted.

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Isotretinoin is a medication used for the treatment of severe acne. It is sometimes used in prevention of certain skin cancers.Isotretinoin noticeably reduces the production of sebum and shrinks the sebaceous glands. It stabilises keratinization and prevents comedones from forming. It also reduces inflammation in moderate-severe inflammatory acne.

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Isotridecan-1-ol is a branched, linear and primary alcohol with high molecular weight. It is a used as a raw material in the industries of cosmetics, drug delivery, metal processing, fiber finish, thermostable and biodegradable lubricant and solvent as well as surfactant.

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Isoxsuprine is a drug used as a vasodilator in humans and equines. It is a beta-adrenergic agonist that causes direct relaxation of uterine and vascular smooth muscle. Therefore, it is used in humans for treatment of premature labour, i.e. a tocolytic.

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Itopride is a prokinetic benzamide derivative unlike metoclopramide or domperidone. These drugs inhibit dopamine and have a gastrokinetic effect. Itopride is indicated for the treatment of functional dyspepsia and other gastrointestinal conditions.

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Itraconazole, invented in 1984, is a triazole antifungal agent that is prescribed to patients with fungal infections. The drug may be given orally or intravenously.

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Ivacaftor is an experimental drug candidate for the treatment of cystic fibrosis. The drug is designed to be effective in patients that have the G551D mutation in the defective protein that causes the disease. The drug is currently in Phase 3 clinical trials and has showed promising results for this subset of cystic fibrosis patients. Cystic fibrosis is caused by a defect in a protein, cystic fibrosis transmembrane conductance regulator, which regulates fluid flow within cells and affects the components of sweat, digestive fluids, and mucus. Ivacaftor potentiates the effect of the defective protein to restore a more normal function.

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