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Lamivudine

Lamivudine is a potent nucleoside analog reverse transcriptase inhibitor (nRTI). It has been used for treatment of chronic hepatitis B at a lower dose than for treatment of HIV. It improves the seroconversion of e-antigen positive hepatitis B and also improves histology staging of the liver. Long term use of lamivudine unfortunately leads to emergence of a resistant hepatitis B virus (YMDD) mutant. Despite this, lamivudine is still used widely as it is well tolerated.

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Lamotrigine

Lamotrigine is an oral anticonvulsant agent developed based on the observation that some antiepileptic drugs possess antifolate activity.It is also used as an adjunct in treating depression, though this is considered off-label usage.Lamotrigine also acts as a mood stabilizer. It is the first medication since lithium granted Food and Drug Administration (FDA) approval for the maintenance treatment of bipolar type I.It inhibits voltage-sensitive sodium channels and/or calcium channels, thereby stabilizing neuronal membranes and consequently modulating presynaptic transmitter release of excitatory amino acids.

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Laninamivir

Laninamivir is a neuraminidase inhibitor which is being researched for the treatment and prophylaxis of Influenzavirus A and Influenzavirus B.

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Lansoprazole

Lansoprazole is a proton-pump inhibitor (PPI) which inhibits the stomach's production of gastric acids. It is a racemic 1:1 mixture of the enantiomers dexlansoprazole (Dexilant, formerly named Kapidex) and levolansoprazole. Lansoprazole is used to treat gastric ulcers caused by a family of pain relievers known as nonsteroidal anti-inflammatory drugs (NSAIDs), and to reduce the risk of gastric ulcers for people who are taking NSAIDs. It is also used to treat conditions associated with the over-production of stomach acid, including Zollinger-Ellison syndrome.

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Lanthanum Carbonate

Lanthanum carbonate is the salt formed by lanthanum(III) cations and carbonate anions. It is an ore of lanthanum metal, along with monazite. It is used in medicine as a phosphate binder. It is prescribed for the treatment of hyperphosphatemia, primarily in patients with chronic kidney disease. It is taken with meals and binds to dietary phosphate, preventing phosphate from being absorbed by the intestine. It is also used for the tinting of glass, for water treatment, or as a catalyst for hydrocarbon cracking.

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Lanthanum Fluoride Industrial Grade 99.999%

Lanthanum fluoride is white face-centered cubic crystal powder, which is rare earth metal fluoride. It is hardly soluble in water, but soluble in alcohol and the dissolution mechanism is same as rare earth chlorides. LaF3 is a kind of optical material. It is stable at room temperature and pressure. Lanthanum oxidelanthanum nitrate or lanthanum chloride is the raw material.

Lanthanum Fluoride

Purity: La/Re 99.999% 5N

CAS No.:13709-38-1 EINECS No.:237-252-8 Molecular Formula:LaF3 Molecular Weight:195.90
Density:5.936 Melting Point:1493℃ Boiling Point:2327℃ UN 3288

Applications

Lanthanum(III) fluoride applies to production of scintillant of modern medical image display and nuclear science requirements, rare earth crystal laser material, fluoride glass optical fiber and rare earth infrared glass. In lighting source, it use in producing carbon electrode of arc lamp. It uses in preparing fluoride ion selective electrode in chemical analysis. In metallurgical industry, it uses in processing special alloy and electrolytic production of lanthanum metal.

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Lapaquistat

Lapaquistat is a cholesterol-lowering drug. Unlike statins, which inhibit HMG-CoA reductase, lapaquistat metabolites inhibit squalene synthase, which is further downstream in the synthesis of cholesterol. It is hoped that side effects can be reduced by not disturbing the mevalonate pathway, which is important for other biochemical molecules besides cholesterol. However, there is increasing evidence that statins may be clinically useful because they affect these other molecules.

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Lapathoside B

Lapathoside B and its derivatives are used in cancer treatment along with other compounds.

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Lapatinib

Lapatinib, used in the form of lapatinib ditosylate, is an orally active drug for breast cancer and other solid tumours. It is a dual tyrosine kinase inhibitor which interrupts the HER2 growth receptor pathway. It is used in combination therapy for HER2-positive breast cancer. It has been approved as front-line therapy in triple positive breast cancer and as an adjuvant therapy when patients have progressed on Herceptin.

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Lapatinib Ditosylate

Lapatinib Ditosylate is a selective and effective inhibitor of ErbB-2 and EGFR dual tyrosine kinases.Lapatinib ditosylate is an anti-cancer drug used for treatment for solid tumours such as breast and lung cancer.

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