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Dihydrexidine is a selective full agonist at the dopamine D1 and D5 receptors. It has approximately 10-fold selectivity for D1 and D5 over the D2 receptor. It was investigated for the treatment of Parkinson's disease and schizophrenia but in an early clinical trial the drug was given intravenously and led to profound hypotension so development was halted. This drug continues to be studied, however, and is now in clinical trials to assess its efficacy in improving the cognitive and working memory deficits in schizophrenia.
Dill Seed Oil is used in herbal formulation as a natural ingredient in gripe waters; raw material in fragrance and flavors.
Dimethyl Urea is used for synthesis of caffeine, theophylline, pharmachemicals.
Dimethylamine is an organic compound. This secondary amine is a colorless, flammable liquified gas with an ammonia-like odor. It is a precursor to several industrially significant compounds. It reacts with carbon disulfide to give dimethyldithiocarbamate, a precursor to a family of chemicals widely used in the vulcanization of rubber. The solvents dimethylformamide and dimethylacetamide are derived from dimethylamine. It is raw material for the production of many agrichemicals and pharmaceuticals, such as dimefox and diphenhydramine, respectively. The surfactant lauryl dimethylamine oxide is found in soaps and cleaning compounds. Unsymmetrical dimethylhydrazine, a rocket fuel, is prepared from dimethylamine.
Dimetridazole is an anti-fungal and anti-protozoal used for the control of infection in pigs, poultry, turkeys, game birds, pigeons and other caged birds.
Diphenylamine is used as a pre or postharvest scald inhibitor for apples.Its anti-scald activity is the result of its antioxidant properties, which protect the apple skin from the oxidation products of alpha-farnesene during storage.They are used as "antiozinates" in the manufacture of rubber products, reflecting the antioxidant nature of aniline derivatives. With sulfur, it gives phenothiazine, a precursor to certain pharmaceuticals. Alkylated diphenylamines function as antioxidants in lubricants, approved for use in machines, in which contact with food is not ruled out.
Doxifluridine is a fluorinated pyrimidine nucleoside, which displays cytostatic activity. It is known that this compound is the inactive form of 5-Fluorouridine, which is converted by enzymes in vivo.
Emtricitabine is a nucleoside reverse transcriptase inhibitor for the treatment of HIV infection in adults and children. Emtricitabine is an analogue of cytidine. Emtricitabine helps to block HIV reverse transcriptase, a chemical in your body (enzyme) that is needed for HIV to multiply. Emtricitabine is always used with other anti-HIV medicines to treat people with HIV infection. Emtricitabine may lower the amount of HIV in the blood (viral load). Emtricitabine may also help to increase the number of T cells called CD4 cells. Emtricitabine works by inhibiting reverse transcriptase, the enzyme that copies HIV RNA into new viral DNA. It is phosphorylated by cellular enzymes to form emtricitabine 5'-triphosphate, which is responsible for the inhibition of HIV-1 reverse transcriptase. It competes with the natural substrate deoxycytidine 5'-triphosphate and incorporates into nascent viral DNA, resulting in early chain termination. Therefore emtricitabine inhibits the activity of HIV-1 reverse transcriptase (RT) both by competing with the natural substrate deoxycytidine 5'-triphosphate and by its incorporation into viral DNA. By inhibiting HIV-1 reverse transcriptase, emtricitabine can help to lower the amount of HIV.
Ethoheptazine is an opioid analgesic from the phenazepine family. It was invented in the 1950s and is related to other drugs such as proheptazine. It produces similar effects to other opioids, including analgesia, sedation, dizziness and nausea.
Ethoxzolamide is a sulfonamide medication that functions as a carbonic anhydrase inhibitor. It is used in the treatment of glaucoma, duodenal ulcers, and as a diuretic. It may also be used in the treatment of some forms of epilepsy.
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