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(+)-JQ-1 analytical pure 0.999

(+)-JQ-1 is a BET bromodomain inhibitor, with IC50 of 77 nM/33 nM for BRD4(1/2) in cell-free assays, binding to all bromodomains of the BET family, but not to bromodomains outside the BET family.

ACY-1215 analytical pure 0.992

ACY-1215 is a selective HDAC6 inhibitor with IC50 of 5 nM, being > 10-fold selective for HDAC6 than HDAC1/2/3 (IC50 = 58, 48, and 51 nM) with slight activity against HDAC8, minimal activity against HDAC4/5/7/9/11, Sirtuin1, and Sirtuin2.

ARRY-162 analytical pure 0.999

ARRY-162 is a potent inhibitor of MEK1/2 with IC50 of 12 nM in a cell-free assay.

Axitinib analytical pure 0.995

Axitinib is a multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFRβ and c-Kit with IC50 of 0.1 nM, 0.2 nM, 0.1-0.3 nM, 1.6 nM and 1.7 nM in Porcine aorta endothelial cells, respectively.

BMS-754807 analytical pure 98%

BMS-754807 is a potent and reversible inhibitor of IGF-1R/InsR with IC50 of 1.8 nM/1.7 nM, less potent to Met, Aurora A/B, TrkA/B and Ron, and shows little activity to Flt3, Lck, MK2, PKA, PKC etc.

BP-1-102 analytical pure 0.996

BP-1-102 is an orally available, small-molecule inhibitor of transcription factor STAT3.

CHIR-98014 analytical pure 98%

CHIR-98014 (CT98014) is highly selective aminopyrimidine-derivatived inhibitor of GSK-3 with IC50 of 650nM and 580nM for GSK-3 and GSK-3(measured by kinase assays), respectively, and exhibits >1000-fold selectivity for GSK-3 over closely related kinases, such as cdc2.

CUDC-907 analytical pure 0.998

CUDC-907 is a dual PI3K and HDAC inhibitor for PI3Kα and HDAC1/2/3/10 with IC50 of 19 nM and 1.7 nM/5 nM/1.8 nM/2.8 nM, respectively.

Chlorpromazine Hydrochloride

Chlorpromazine Hydrochloride is the hydrochloride salt form of chlorpromazine, a phenothiazine and traditional antipsychotic agent with anti-emetic activity.Chlorpromazine Hydrochloride exerts its antipsychotic effect by blocking postsynaptic dopamine receptors in cortical and limbic areas of the brain.

Crenolanib analytical pure 98%

Crenolanib is a potent class III RTKs inhibitor with Kd values of 3.2nM, 2.1nM and 0.74nM for PDGFRα, PDGFRβ and FLT3.

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