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Methyldihydromorphine is a semi-synthetic opioid drug developed in Germany in 1936, controlled under both domestic law and UN conventions because of its possible potential for abuse. It is related to heterocodeine and is not a synonym for dihydrocodeine, and its structure suggests that it is six to nine times stronger than morphine and 72 times stronger than dihydrocodeine.
Methyldopa is an alpha-adrenergic agonist psychoactive drug used as a sympatholytic or antihypertensive. Its use is now mostly deprecated following the introduction of alternative safer classes of agents. Methyldopa is in a class of medications called antihypertensives. It works by relaxing the blood vessels so that blood can flow more easily through the body. Methyldopa is used to treat high blood pressure. Methyldopa exhibits variable absorption from the gastrointestinal tract. It is metabolized in the liver and intestines and is excreted in urine.
Methylene blue is an heterocyclic aromatic chemical compound.It is used to treat ich. It is used as a pathological stain and as a diagnostic aid in the detection of the premature rupture of fetal membranes and to identify separate amniotic sacs in multiple pregnancies. It is used as a biological and bacteriological stain, oxidation-reduction indicator as well.
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Methylmorpholine is an organic base.It is used in the preparation of N-methylmorpholine N-oxide,rubber chemicals,sulfonamide bactericide,colourants for hair dyes and blueprints,polyurethane foams, elastomers and adhesives.It is also used as a pH adjustment additive in fossil fuel and steam systems as a corrosion inhibitor
Methylnaltrexone is one of the newer agents of peripherally-acting μ-opioid antagonists that act to reverse some of the side effects of opioid drugs such as constipation without affecting analgesia or precipitating withdrawals. Because it contains a permanently charged tetravalent nitrogen atom, it cannot cross the blood-brain barrier, and so has antagonist effects throughout the body, counteracting effects such as itching and constipation, but without affecting opioid effects in the brain such as analgesia. However, since a significant fraction of opioid analgesia can be mediated by opioid receptors on peripheral sensory neurons, particularly in inflammatory conditions such as arthritis, traumatic or surgical pain, MNTX may increase pain under such circumstances.
Methylone is an entactogen and stimulant of the phenethylamine, amphetamine, and cathinone classes.It acts as a mixed reuptake inhibitor or releasing agent of serotonin, norepinephrine, and dopamine.
Methysticin is one of the six major kavalactones found in the kava plant.
Metiamide is a histamine H2-receptor antagonist developed from another H2 antagonist, burimamide. It was an intermediate compound in the development of the successful anti-ulcer drug cimetidine. It reduces basal and nocturnal gastric acid secretion and a reduction in gastric volume, acidity, and amount of gastric acid released in response to stimuli including food, caffeine, insulin, betazole, or pentagastrin. Metiamide inhibits many of the isoenzymes of the hepatic CYP450 enzyme system. Other actions of Metiamide include an increase in gastric bacterial flora such as nitrate-reducing organisms.
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