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Narcotoline is an opiate alkaloid chemically related to noscapine. It binds to the same receptors in the brain as noscapine to act as an antitussive, and has also been used in tissue culture media. It can be obtained from the opium poppy, Papaver somniferum.
Naringenin is a flavanone, a type of flavonoid, that is considered to have a bioactive effect on human health as antioxidant, free radical scavenger, anti-inflammatory, carbohydrate metabolism promoter, and immune system modulator. It is the predominant flavanone in grapefruit.
Natamycin is a naturally occurring antifungal agent produced during fermentation by the bacterium Streptomyces natalensis, commonly found in soil. Natamycin has a very low solubility in water, due to the amphiphilic nature of the molecule. However, natamycin is effective at very low levels. Natamycin is classified as a macrolide polyene antifungal and, as a drug, is used to treat fungal keratitis. It is especially effective against Aspergillus and Fusarium corneal infections.
Nateglinide is a drug for the treatment of type 2 diabetes.Nateglinide belongs to the meglitinide class of blood glucose-lowering drugs. Nateglinide lowers blood glucose by stimulating the release of insulin from the pancreas. It achieves this by closing ATP-dependent potassium channels in the membrane of the β cells. This depolarizes the β cells and causes voltage-gated calcium channels to open. The resulting calcium influx induces fusion of insulin-containing vesicles with the cell membrane, and insulin secretion occurs.
Nebivolol is a β1 receptor blocker with nitric oxide-potentiating vasodilatory effect used in treatment of hypertension and, in Europe, also for left ventricular failure.It is highly cardioselective under certain circumstances.Nebivolol lowers blood pressure (BP) by reducing peripheral vascular resistance, and significantly increases stroke volume with preservation of cardiac output.
Nebivolol Hydrochloride acts as a selective β1-adrenoceptor antagonist.Induces vasodilation via a nitric oxide- and cGMP-dependent mechanism and displays antihypertensive activity.
Nedaplatin is a platinum compound which is used for cancer chemotherapy. It produces less nausea, vomiting and nephrotoxicity than other platinum-containing drugs.
Neem Oil is used in pharmaceutical aid, health tonics, blood purifier, ayurvedic and herbal preparations, as a natural insecticide.
Nefazodone is an antidepressant. Its sale was discontinued in 2003 in some countries due to the rare incidence of hepatotoxicity, which could lead to the need for a liver transplant, or even death.
Nelfinavir is a potent HIV protease inhibitor. It is used in combination with other antiviral drugs in the treatment of HIV in both adults and children.Nelfinavir inhibits the HIV viral proteinase enzyme which prevents cleavage of the gag-pol polyprotein, resulting in noninfectious, immature viral particles.Side effects include thirst and hunger, unexplained weight loss, increased urination, fatigue, and dry, itchy skin.
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