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SNX-2112 analytical pure 0.999

SNX-2112 is a potent synthetic heat shock protein 90 (HSP90) inhibitor with an IC50 of 0.92 μM for K562 cells.

Sorafenib analytical pure 0.99

Sorafenib is a multikinase inhibitor of Raf-1, B-Raf and VEGFR-2 with IC50 of 6 nM, 22 nM and 90 nM in cell-free assays, respectively.

Tariquidar analytical pure 98%

Tariquidar is a potent and selective noncompetitive inhibitor of P-glycoprotein with Kd of 5.1 nM, reverses drug resistance in MDR cell Lines.

Z-IETD-FMK analytical pure 98%

Z-IETD-FMK is a specific Caspase-8 inhibitor.

A-1210477 analytical pure 0.999

A-1210477 is a potent and selective inhibitor of MCL-1, and weakly binds to BCL-2 and BCL-XL, with Ki of 0.45 nM, 132 nM and > 660 nM, respectively.

AS-1517499 analytical pure 0.98

AS-1517499 is a potent STAT6 inhibitor with IC50 of 21 nM.

AS-703026 analytical pure 0.998

AS7-03026 is a highly selective, potent, ATP non-competitive allosteric inhibitor of MEK1/2 with IC50 of 5 nM-2 μM in MM cell lines.

Alectinib analytical pure 0.998

Alectinib is a potent ALK inhibitor with IC50 of 1.9 nM while also inhibits F1174L, R1275Q, and L1196M mutants of ALK (IC50s = 1.0, 3.5, and 1.6 nM, respectively).

Alpelisib analytical pure 0.999

Alpelisib is a potent and selective PI3Kα inhibitor with IC50 of 5 nM, liitle or no effect on PI3Kβ/γ/δ.

BIBF 1120 analytical pure 0.999

BIBF 1120 is a multi-RTKs inhibitor with IC50 values of 13nM, 13nM , 16nM , 26nM , 34nM , 37nM , 59nM , 65nM , 69nM , 108nM for VEGFR2, VEGFR3, LCK, FLT3, VEGFR1, FGFR2, PDGFRα, PDGFRβ, FGFR1, FGFR3, less potent to Src, Lyn and FGFR4 with IC50 values of 156nM , 195nM and 610nM, respectively.

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