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Pinnacle LC 190 Petrolatum, USP

Pinnacle LC 190 petrolatum, USP is an opaque, white semi-solid with a typical consistency of 190 dmm.It as functions such as Lubrication, moisture resistance/retention, conditioning.Pinnacle LC 190 petrolatum, USP is used in food, pharmaceutical, personal xare, pet care, specialty industries.

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Pioglitazone

Pioglitazone is used for the treatment of diabetes mellitus type 2. Pioglitazone selectively stimulates nuclear receptor peroxisone proliferator-activated receptor gamma (PPAR-gamma). It modulates the transcription of the insulin-sensitive genes involved in the control of glucose and lipid metabolism in the lipidic, muscular tissues and in the liver.Pioglitazone acts as an agonist at peroxisome proliferator activated receptors (PPAR) in target tissues for insulin action such as adipose tissue, skeletal muscle, and liver. Activation of PPAR-gamma receptors regulates the transcription of insulin-responsive genes involved in the control of glucose production, transport, and utilization. In this way, pioglitazone enhances tissue sensitivity to insulin.Possible hazard hypogycemia

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Piperaquine

Piperaquine is an antimalarial drug, a bisquinoline first synthesised in the 1960s, and used extensively in China and Indochina as prophylaxis and treatment during the next 20 years. Usage declined in the 1980s as piperaquine-resistant strains of P. falciparum arose and artemisinin-based antimalarials became available. However, Chinese scientists discovered that piperaquine was suitable for artemisinin combination therapies.

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Piperazine

Piperazine is an organic compound that consists of a six-membered ring containing two opposing nitrogen atoms. It was first introduced as an anthelmintic in 1953. It is used in the manufacture of plastics, resins, pesticides, brake fluid and other industrial materials. It is also a fluid used for CO2 and H2S scrubbing in association with methyl diethanolamine.

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Piperazine Citrate

Piperazine Citrate is used in Anthelmintics or Antinematodal agents.

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Piperidine

Piperidine is an organic compound. This heterocyclic amine consists of a six-membered ring containing five methylene units and one nitrogen atom. It is a widely used building block and chemical reagent in the synthesis of organic compounds, including pharmaceuticals. It is used as a solvent and as a base. A significant industrial application of piperidine is for the production of dipiperidinyl dithiuram tetrasulfide, which is used as a rubber vulcanization accelerator.

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Piperocaine

Piperocaine is a local anesthetic drug used as its hydrochloride salt for infiltration and nerve blocks.

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Piracetam

Piracetam is a nootropic drug. It is a cyclic derivative of GABA. It is one of the group of racetams. Piracetam acts on the central nervous system. It is thought to protect the part of the brain called the cerebral cortex against a lack of oxygen. Piracetam is used alongside other medicines in the treatment of cortical myoclonus. Piracetam improves the function of the neurotransmitter acetylcholine via muscarinic cholinergic (ACh) receptors which are implicated in memory processes. It appears to reverse the effects of aging in the brains of mice, reduce levels of lipofuscin in the rat brain, and effective in treating cognitive impairment in alcoholism, effective for improving cognition in Alzheimer's disease and senile dementia patients. Piracetam is useful as a long-term treatment for clotting, coagulation, and vasospastic disorders such as Raynaud's phenomenon and deep-vein thrombosis. It is an extremely safe anti-thrombotic agent that operates through the novel mechanism of inhibiting platelet aggregation and enhancing blood-cell deformability.

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Pirarubicin

Pirarubicin is an anthracycline drug. It intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. This agent is less cardiotoxic than doxorubicin and exhibits activity against some doxorubicin-resistant cell lines.

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Pirfenidone

Pirfenidone is a drug used for the treatment of idiopathic pulmonary fibrosis (IPF).Pirfenidone is administered orally. Pirfenidone has well-established antifibrotic and anti-inflammatory properties in various in vitro systems and animal models of fibrosis. Pirfenidone has also been shown to reduce production of inflammatory mediators such as TNF-α and IL-1β in both cultured cells and isolated human peripheral blood mononuclear cells. Pirfenidone is frequently associated with gastrointestinal side effects such as dyspepsia, nausea, gastritis, gastroesophageal reflux disease (GERD) and vomiting. Pirfenidone is known to cause photosensitivity reactions, rash, pruritus and dry skin, increases hepatic enzyme levels.

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