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Pyrazole

Pyrazole refers both to the class of simple aromatic ring organic compounds of the heterocyclic diazole series characterized by a 5-membered ring structure composed of three carbon atoms and two nitrogen atoms in adjacent positions, and to the unsubstituted parent compound. Being so composed and having pharmacological effects on humans, they are classified as alkaloids, although they are rare in nature. In 1959, the first natural pyrazole, 1-pyrazolyl-alanine, was isolated from seeds of watermelons. The term pyrazole was given to this class of compounds by Ludwig Knorr in 1883. In medicine, derivatives of pyrazoles are used for their analgesic, anti-inflammatory, antipyretic, antiarrhythmic, tranquilizing, muscle relaxing, psychoanaleptic, anticonvulsant, monoamineoxidase inhibiting, antidiabetic and antibacterial activities.

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Pyridine

Pyridine is a basic heterocyclic organic compound. It was discovered in 1849 by the Scottish chemist Thomas Anderson as one of the constituents of bone oil. Two years later, Anderson isolated pure pyridine through fractional distillation of the oil. It is used as a precursor to agrochemicals and pharmaceuticals and is also an important solvent and reagent. Pyridine is added to ethanol to make it unsuitable for drinking. It is used in the synthesis of sulfapyridine, antihistaminic drugs tripelennamine and mepyramine, as well as water repellents, bactericides and herbicides.

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Pyridinium Tribromide

Pyridinium tribromide is used as a brominating agent for organic synthesis especially for pharmaceuticals and hormones. It can be replaced for n-Bromosuccinimide.

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Pyridoxine

Pyridoxine is one of the compounds that can be called vitamin B6,along with pyridoxal and pyridoxamine . Pyridoxine assists in the balancing of sodium and potassium as well as promoting red blood cell production. Pyridoxine may help balance hormonal changes in women and aid the immune system. Lack of pyridoxine may cause anemia, nerve damage, seizures, skin problems, and sores in the mouth.

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Pyridoxine Hydrochloride

Pyridoxine hydrochloride is one of the vitamins of the B6 complex; present in many foodstuffs. It is used as an additive for cosmetics, promotes growth of hair and protects the skin.

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Pyrimethamine

Pyrimethamine is a medication used for protozoal infections. It is commonly used as an antimalarial drug, and is also used, in combination with sulfadiazine, in the treatment of Toxoplasma gondii infections in immunocompromised patients, such as HIV-positive individuals.Pyrimethamine inhibits the dihydrofolate reductase of plasmodia and thereby blocks the biosynthesis of purines and pyrimidines, which are essential for DNA synthesis and cell multiplication. This leads to failure of nuclear division at the time of schizont formation in erythrocytes and liver.

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Pyrithioxin

Pyritinol is a semi-natural water soluble analog of vitamin B6. It was produced in 1961 by Merck Laboratories by bonding 2 vitamin B6 compounds together with a disulfide bridge. It is approved for symptomatic treatment of chronically impaired brain function in dementia syndromes and for supportive treatment of sequelae of craniocerebral trauma in various European countries.

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QuatVet

QuatVet is quaternary Ammonium based disinfectant and used for disinfection of poultry and livestock farms, particularly effective against gram positive and gram negative bacteria, and enveloped viruses.

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Quazepam

Quazepam is a drug which is a benzodiazepine derivative. It is indicated for the treatment of insomnia including sleep induction and sleep maintenance. It induces impairment of motor function and has hypnotic and anticonvulsant properties with less overdose potential than other benzodiazepines. It is an effective hypnotic which induces and maintains sleep without disruption of the sleep architecture. It is a trifluoroethyl type of benzodiazepine. It is unique amongst benzodiazepines in that it selectively targets the GABAA type1 receptors which are responsible for inducing sleep. Its mechanism of action is very similar to zolpidem and zaleplon in its pharmacology and can successfully substitute for zolpidem and zaleplon in animal studies.

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Quazinone

Quazinone is a cardiotonic and vasodilator drug which was developed and marketed in the 1980s for the treatment of heart disease. It acts as a selective PDE3 inhibitor. It is no longer available.

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