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Quazinone

Quazinone is a cardiotonic and vasodilator drug which was developed and marketed in the 1980s for the treatment of heart disease. It acts as a selective PDE3 inhibitor. It is no longer available.

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Quercetin

Quercetin, a flavonol, is a plant-derived flavonoid found in fruits, vegetables, leaves and grains. It also may be used as an ingredient in supplements, beverages or foods. From in vitro studies, quercetin has demonstrated significant anti-inflammatory activity by inhibiting both synthesis and release of histamine and other allergic/inflammatory mediators. In addition, it may have antioxidant activity and vitamin C-sparing action.

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Quetiapine

Quetiapine is an atypical antipsychotic approved for the treatment of schizophrenia, bipolar disorder and as an add-on to treat depression.Quetiapine is a selective monoaminergic antagonist with high affinity for the serotonin Type 2 (5HT2), and dopamine type 2 (D2) receptors. Quetiapine is an antagonist at serotonin 5-HT1A and 5HT2, dopamine D1 and D2, histamine H1, and adrenergic alpha 1 and alpha 2 receptors. Quetiapine has no significant affinity for cholinergic muscarinic or benzodiazepine receptors. Drowsiness and orthostatic hypotension associated with use of quetiapine may be explained by its antagonism of histamine H1 and adrenergic alpha 1 receptors, respectively. Quetiapine's antagonism of adrenergic a1 receptors may explain the orthostatic hypotension observed with this drug.

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Quinacrine

Quinacrine is a drug with a number of different medical applications. It is related to mefloquine. Its main effects are as an antiprotozoal, antirheumatic and an intrapleural sclerosing agent. It is also used "off-label" for the treatment of systemic lupus erythematosus, indicated in the treatment of discoid and subcutaneous lupus erythematosus, particularly in patients unable to take chloroquine derivatives. As an intrapleural sclerosing agent, it is used as pneumothorax prophylaxis in patients at high risk of recurrence.

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Quinagolide

Quinagolide is a selective, D2 receptor agonist that is used for the treatment of elevated levels of prolactin.

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Quinaldine

Quinaldine is used in anti-malaria drugs, in manufacturing dyes, food colorants (e.g. Quinoline Yellow WS), pharmaceuticals, pH indicators. Quinaldine sulfate is an anaesthetic used in fish transportation.

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Quinapril

Quinapril is used in the treatment of hypertension and congestive heart failure. Quinapril is actually a prodrug. It is converted to its active metabolite, quinaprilat, in the liver. Quinapril inhibits angiotensin converting enzyme, an enzyme which catalyses the formation of angiotensin II from its precursor, angiotensin I. Angiotensin II is a powerful vasoconstrictor and increases blood pressure through a variety of mechanisms.Quinaprilat competes with angiotensin I for binding at the angiotensin-converting enzyme, blocking the conversion of angiotensin I to angiotensin II.Overdose may lead to severe hypotension.

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Quinethazone

Quinethazone is a thiazide diuretic used to treat hypertension. Common side effects include dizziness, dry mouth, nausea, and low potassium levels.

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Quinine

Quinine is a natural white crystalline alkaloid having antipyretic,antimalarial, analgesic (painkilling), anti-inflammatory properties and a bitter taste. It is a stereoisomer of quinidine which, unlike quinine, is an anti-arrhythmic. Quinine contains two major fused-ring systems: the aromatic quinoline and the bicyclic quinuclidine.Quinine is used parenterally to treat life-threatening infections caused by chloroquine-resistant Plasmodium falciparum malaria. Quinine acts as a blood schizonticide although it also has gametocytocidal activity against P. vivax and P. malariae.

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Quinolinic Acid

Quinolinic acid is a dicarboxylic acid. It used in the manufacture of pharmaceutically effective compounds.

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