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Reboxetine

Reboxetine is an antidepressant drug used in the treatment of clinical depression, panic disorder and ADD/ADHD. Its mesylate (i.e. methanesulfonate) salt is sold under tradenames including Edronax, Norebox, Prolift, Solvex, Davedax or Vestra.Reboxetine is a selective inhibitor of noradrenaline reuptake. It inhibits noradrenaline reuptake in vitro to a similar extent to the tricyclic antidepressant desmethylimipramine. Reboxetine does not affect dopamine or serotonin reuptake and it has low in vivo and in vitro affinity for adrenergic, cholinergic, histaminergic, dopaminergic and serotonergic receptors.Symptoms of overdose include seizures (rare).

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Reboxetine LAB GRADE 97%

Reboxetine, also called as Vestra, 2-((2-ethoxyphenoxy)benzyl)morpholine methanesulfonate, exists as two enantiomers, (R,R)-(-)- and (S,S)-(+)-reboxetine. Ti is a selective norepinephrine reuptake inhibitor used in the treatment of clinical depression, panic disorder and ADD/ADHD which has been approved for treatment of major depression.
In vitro: it inhibits noradrenaline reuptake in vitro to a similar extent to the tricyclic antidepressant desmethylimipramine and does not inhibit the activity of the following isozymes of cytochrome P450: CYP1A2, CYP2C9, CYP2C19, and CYP2E1;
In vivo: Reboxetine does not affect dopamine or serotonin reuptake and it has low in vivo and in vitro affinity for adrenergic, cholinergic, histaminergic, dopaminergic and serotonergic receptors.Besides, it inhibits both CYP2D6 and CYP3A4 with low binding affinities, but has shown no effect on the in vivo clearance of drugs metabolized by these enzymes. http://www.bocsci.com/reboxetine-cas-98769-81-4-item-283151.html

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Reboxetine mesylate LAB GRADE 97%

Reboxetine mesylate is  a potent and selective inhibitor of noradrenalin uptake (K i values are 1.1, 129 and > 10000 nM for rat NET, SERT and DAT respectively). Displays > 1000-fold selectivity over α -adrenoceptors, 5-HT, dopamine and muscarinic ACh receptors. 
Norepinephrine: IC50 = 8.2 nM; 5-HT: IC50 = 1.07 µM; H1: IC50 = 1.4 µM; α1 Adrenergic: IC50 = 10 µM

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Reclazepam

Reclazepam is a drug which is a benzodiazepine derivative. It has sedative and anxiolytic effects similar to those produced by other benzodiazepine derivatives, and has a short duration of action.

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Refined Glycerine Technical 99.7%

Versatile Bangladesh is a Chemical Import and Export Industry. In 2012 the company has restructure the company segregate with two concern  one Versatile Bangladesh involve in import of basic industrial commodities and another company Alisha International for import- export of consumer product.

Versatile Bangladesh is not only a Importer and supplier company; we are also seeking to do a total solution provider with international sourcing of industrial commodities. Quality assurance and supply chain management with professional technical support. We specialize in importing of all kinds of Textile & Leather Chemicals and Dyes.

 

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Regadenoson

Regadenoson is an A2A adenosine receptor agonist that is a coronary vasodilator. It produces maximal hyperemia quickly and maintains it for an optimal duration that is practical for radionuclide myocardial perfusion imaging.

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Regorafenib

Regorafenib is an orally bioavailable small molecule with potential antiangiogenic and antineoplastic activities. Regorafenib binds to and inhibits vascular endothelial growth factor receptors (VEGFRs) 2 and 3, and Ret, Kit, PDGFR and Raf kinases, which may result in the inhibition of tumor angiogenesis and tumor cell proliferation.

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Remifentanil

Remifentanil is a potent, short-acting synthetic opioid analgesic drug. It is given to patients during surgery to relieve pain and as an adjunct to an anaesthetic. Remifentanil is used for sedation as well as combined with other medications for use in general anesthesia. Remifentanil is used as an opioid analgesic that has a rapid onset and rapid recovery time.It has been used effectively during craniotomies,spinal surgery,cardiac surgery,and gastric bypass surgery.Remifentanil can be administered as part of an anesthesia technique called TIVA (Total Intravenous Anesthesia) using computer controlled infusion pumps in a process called target controlled infusion (TCI).Remifentanil is approximately twice as potent as fentanyl, and 100-200 times as potent as morphine.Remifentanil has been used with some success to circumvent naltrexone in patients who are in need of pain management.

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Remogliflozin Etabonate

Remogliflozin etabonate is a proposed drug for the treatment of type 2 diabetes. It inhibits the sodium-glucose transport proteins, which are responsible for glucose reabsorption in the kidney. Blocking this transporter causes blood glucose to be eliminated through the urine.

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Remoxipride

Remoxipride is an atypical antipsychotic which was previously used in Europe for the treatment of schizophrenia but was withdrawn due to toxicity concerns. It was initially launched by AstraZeneca in 1990 and suspension of its use began in 1993. It acts as a selective D2 and D3 receptor antagonist and also has high affinity for the sigma receptor, possibly playing a role in its atypical neuroleptic action.

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