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Tepotinib analytical pure 0.998

Tepotinib is a selective c-Met inhibitor with IC50 value of 3nM, over 200-fold against IRAK4, TrkA, Axl, IRAK1, Mer, TrkB and Ron.

Veliparib analytical pure 0.996

Veliparib is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM and 2.9 nM, respectively.

AR-C155858 analytical pure 0.994

AR-C155858 is an inhibitor of the monocarboxylate transporters (MCTs) MCT1 and MCT2 (Ki values are 2.3 and < 10 nM, respectively), and exhibits no activity at MCT4.

Apoptozole analytical pure 0.999

Apoptozole is an inhibitor of heat shock protein 70 (HSP70) and Hsc70. It induces caspase-dependent apoptosis.

Belinostat analytical pure 0.996

Belinostat is a pan-HDAC inhibitor with IC50 of 27 nM, with activity demonstrated in cisplatin-resistant tumors.

Belinostat analytical pure 0.999

Belinostat is a HDAC inhibitor with IC50 of 27 nM in a cell-free assay, with activity demonstrated in cisplatin-resistant tumors.

Betamethasone Sodium Phosphate

Betamethasone Sodium Phosphate is an organic sodium salt that is the disodium salt of betamethasone phosphate. It is an organic sodium salt and a tertiary alpha-hydroxy ketone.Betamethasone sodium phosphate binds to specific intracellular glucocorticoid receptors and subsequently binds to DNA to modify gene expression.

Copanlisib analytical pure 0.999

Copanlisib is a potent and highly selective reversible PI3K inhibitor for PI3Kα/β with IC50 of 0.469 nM/3.72 nM.

Crizotinib analytical pure 0.999

Crizotinib is a potent inhibitor of c-Met and ALK with IC50 of 11 nM and 24 nM, respectivley.

Cytarabine analytical pure 0.999

Cytarabine is an antimetabolic agent and DNA synthesis inhibitor with IC50 of 16 nM in wild-type CCRF-CEM cells.

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