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Verapamil

Verapamil is a calcium channel blocker that is a class IV anti-arrhythmia agent.

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Veratraldehyde

Veratradehyde is a derivative of benzaldehyde with two methoxy groups.It is used for synthesis of Verazine , Methyldopa, Methyldopate, Carbidopa,Diaveridine,perfumes,fragrances.

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Veratric Acid

Veratric Acid is a very important pharmaceutical intermediates,synthetic for functional dyspepsia FD Itopride hydrochloride, 6-Nitroveratriceacid.

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Veratrole

Veratrole is the dimethyl ether derived from pyrocatechol.It is a very important pharmaceutical intermediates, mainly used for drug synthesis of angiocardiopathy, such as Dopamine Hydrochloride, palmatine, verapamil, etc.Veratrole also can be used for synthesis of Veratraldehyde, thus methyldopa, including more than, Prazosin hydrochloride,Donepezil Hydrochloride,Homoveratonitrile, Homoverylamine and other important intermediates.Veratrole is an important pesticide intermediates.

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Veratryl alcohol

veratryl (3,4-dimethoxybenzyl) alcohol, which is a secondary metabolite of this fungus.Ligninase activity increased 2 to 4 h after the addition of exogenous veratryl alcohol to ligninolytic cultures

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Verbascoside

Verbascoside is a phenylethanoid and a caffeic acid sugar ester. It has an antimicrobial activity, notably against Staphylococcus aureus. It can also have anti-inflammatory properties. It shows a genotoxicity on human lymphocytes with an involvement of PARP-1 and p53 proteins. It is a protein kinase C inhibitor.

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Vigabatrin

Vigabatrin is an analogue of gamma-aminobutyric acid. It is an irreversible inhibitor of 4-aminobutyrate transaminase, the enzyme responsible for the catabolism of gamma-aminobutyric acid.Vigabatrin, is an anticonvulsant chemically unrelated to other anticonvulsants.It inhibits the catabolism of GABA. It is an analog of GABA, but it is not a receptor agonist. Vigabatrin irreversibly inhibits the enzyme GABA transaminase.It increases brain concentrations of gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter in the CNS, by irreversibly inhibiting enzymes that catabolize GABA (gamma-aminobutyric acid transaminase GABA-T) or block the reuptake of GABA into glia and nerve endings. Vigabatrin may also work by suppressing repetitive neuronal firing through inhibition of voltage-sensitive sodium channels.

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Vilazodone

Vilazodone is a novel compound with combined high affinity and selectivity for the 5-hydroxytryptamine (5-HT) transporter and 5-HT receptors. It has been shown to be equally efficacious as other antidepressants with similar gastrointestinal side effects and possibly with reduced sexual side effects and weight gain. Vilazodone is an antidepressant agent that can used as an alternative for patients who cannot tolerate therapy with other antidepressant classes such as selective serotonin reuptake inhibitors or serotonin norepinephrine reuptake inhibitors. Treatment should be titrated towards the target dose, which is 40mg per day.Vilazodone increases serotonin levels in the brain by inhibiting the reuptake of serotonin while acting as a partial agonist on serotonin-1A receptors. It has therefore been coined by scientists as a selective partial agonist and reuptake inhibitor (SPARI).

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Viminol

Viminol is an opioid analgesic developed by the drugs company Zambon in the 1960s. It has an unusual chemical structure that is not similar to other opioids. It has both antitussive and analgesic effects. It has six different stereoisomers which have varying properties, with the 2-(R) isomer being a μ-opioid full agonist around 5 times more potent than morphine, while the 2-(S) isomer is an antagonist. Since vimonol is supplied as a racemic mixture of isomers, the overall effect produces a mixed agonist-antagonist profile similar to that of opioids such as pentazocine, although with somewhat less side effects. It has similar effects to other opioids, and produces analgesia, sedation and euphoria.

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Vincristine

Vincristine is a chemotherapy medication used to treat a number of types of cancer.It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system.It is a vinca alkaloid that can be obtained from the Madagascar periwinkle Catharanthus roseus.Vincristine is delivered via intravenous infusion for use in various types of chemotherapy regimens.Its main uses are in non-Hodgkin's lymphoma as part of the chemotherapy regimen CHOP, Hodgkin's lymphoma as part of MOPP, COPP, BEACOPP, or the less popular Stanford V chemotherapy regimen in acute lymphoblastic leukemia (ALL), and in treatment for nephroblastoma.It is also used to induce remission in ALL with dexamethasone and L-Asparaginase, and in combination with prednisone to treat childhood leukemia.Vincristine's main side effects of vincristine are chemotherapy-induced peripheral neuropathy, hyponatremia, constipation, and hair loss.Vincristine works partly by binding to the tubulin protein, stopping the cell from separating its chromosomes during the metaphase; the cell then undergoes apoptosis.

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